scholarly journals Self-assembled, ellipsoidal polymeric nanoparticles for intracellular delivery of therapeutics

2018 ◽  
Vol 106 (7) ◽  
pp. 2048-2058 ◽  
Author(s):  
Prachi Desai ◽  
Anjana Venkataramanan ◽  
Rebecca Schneider ◽  
Manish K. Jaiswal ◽  
James K. Carrow ◽  
...  
2006 ◽  
Vol 17 (4) ◽  
pp. 920-927 ◽  
Author(s):  
James B. Delehanty ◽  
Igor L. Medintz ◽  
Thomas Pons ◽  
Florence M. Brunel ◽  
Philip E. Dawson ◽  
...  

2010 ◽  
Vol 10 (5) ◽  
pp. 3551-3556 ◽  
Author(s):  
Mi-Kyong Yoo ◽  
Min-Yim Park ◽  
Sang-Wha Lee ◽  
Yun-Jaie Choi ◽  
In-Kyu Park ◽  
...  

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Ana Cadete ◽  
Ana Olivera ◽  
Magnus Besev ◽  
Pradeep K. Dhal ◽  
Lídia Gonçalves ◽  
...  

Biomaterials ◽  
2012 ◽  
Vol 33 (7) ◽  
pp. 2310-2320 ◽  
Author(s):  
Jing Li ◽  
Meirong Huo ◽  
Jing Wang ◽  
Jianping Zhou ◽  
Jumah M. Mohammad ◽  
...  

Author(s):  
Wujie Zhang ◽  
Jianhua Rong ◽  
Qian Wang ◽  
Xiaoming He

Recently, polymeric nanoparticles have attracted tremendous interests as a useful tool to encapsulate therapeutic drugs, genes, and proteins for their controlled and sustained delivery. Among them, polymeric hydrogel nanoparticles with thermal and/or pH responsiveness have attracted particular attention [1]. Trehalose, a non-reducing disaccharide of glucose, has been demonstrated to be a potent, nontoxic bioprotectant for stabilizing lipids, proteins, viruses, and blood cells at cryogenic and particularly, ambient temperatures (i.e., cryo and lyopreservation) [2]. However, intracellular delivery of trehalose into small eukaryotic mammalian cells in a large quantity for biostabilization purpose has not been very successful so far [2]. In this study, a thermally responsive polymeric nanocapsule was synthesized and characterized with the aim to encapsulate trehalose for its intracellular delivery.


Polymer ◽  
2000 ◽  
Vol 41 (16) ◽  
pp. 6415-6419 ◽  
Author(s):  
T.-W Chung ◽  
J.-W Nah ◽  
T Akaike ◽  
Y.-H Park ◽  
C.-S Cho

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