In vitro cartilage construct generation from silk fibroin- chitosan porous scaffold and umbilical cord blood derived human mesenchymal stem cells in dynamic culture condition

2017 ◽  
Vol 106 (2) ◽  
pp. 397-407 ◽  
Author(s):  
Parinita Agrawal ◽  
Krishna Pramanik ◽  
Amit Biswas ◽  
Ranjan Ku Patra
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Cord Blood ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Culture Condition ◽  
Porous Scaffold ◽  
Human Mesenchymal Stem Cells ◽  
Cartilage Construct

scholarly journals In vitro Expansion of Umbilical Cord Blood Derived Mesenchymal Stem Cells (UCB-MSCs) Under Hypoxic Conditions

2015 ◽  
Vol 21 (1) ◽  
pp. 40-49 ◽  
Author(s):  
Jungyun Yang ◽  
Jihye Kwon ◽  
Miyeon Kim ◽  
Yunkyung Bae ◽  
Hyejin Jin ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Cord Blood ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Hypoxic Conditions ◽  
In Vitro Expansion

Co-culture of Umbilical Cord Blood CD34+Cells with Human Mesenchymal Stem Cells

2006 ◽  
Vol 0 (0) ◽  
pp. 060913044658049
Author(s):  
Yue Zhang ◽  
Chou Chai ◽  
Xue-Song Jiang ◽  
Swee-Hin Teoh ◽  
Kam W. Leong
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Cord Blood ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Human Mesenchymal Stem Cells ◽  
Cd34 Cells ◽  
Cord Blood Cd34

scholarly journals Galectin-3 Secreted by Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Reduces Amyloid-Beta42 Neurotoxicity In Vitro

2011 ◽  
Vol 100 (3) ◽  
pp. 415a ◽  
Author(s):  
Ju-Yeon Kim ◽  
Dong Hyun Kim ◽  
Dal-Soo Kim ◽  
Ji Hyun Kim ◽  
Sang Young Jeong ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Cord Blood ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Human Umbilical Cord Blood ◽  
Human Umbilical Cord ◽  
Galectin 3

Inducing hepatogenic differentiation of human mesenchymal stem cells derived from umbilical cord blood

2014 ◽  
Vol 39 (1) ◽  
pp. 6
Author(s):  
DareenA Mohamed ◽  
MoustafaZ Moustafa ◽  
GhadaM Balah ◽  
EnasA Elzamarany ◽  
NahlaA Nosair
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Cord Blood ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Human Mesenchymal Stem Cells ◽  
Hepatogenic Differentiation

scholarly journals Preclinical Evaluation of the Immunomodulatory Properties of Cardiac Adipose Tissue Progenitor Cells Using Umbilical Cord Blood Mesenchymal Stem Cells: A Direct Comparative Study

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Isaac Perea-Gil ◽  
Marta Monguió-Tortajada ◽  
Carolina Gálvez-Montón ◽  
Antoni Bayes-Genis ◽  
Francesc E. Borràs ◽  
...  
Keyword(s):  
Stem Cells ◽  
Immune Response ◽  
Mesenchymal Stem Cells ◽  
Cord Blood ◽  
Progenitor Cells ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Dependent Manner ◽  
Immunomodulatory Properties

Cell-based strategies to regenerate injured myocardial tissue have emerged over the past decade, but the optimum cell type is still under scrutiny. In this context, human adult epicardial fat surrounding the heart has been characterized as a reservoir of mesenchymal-like progenitor cells (cardiac ATDPCs) with potential clinical benefits. However, additional data on the possibility that these cells could trigger a deleterious immune response following implantation are needed. Thus, in the presented study, we took advantage of the well-established low immunogenicity of umbilical cord blood-derived mesenchymal stem cells (UCBMSCs) to comparatively assess the immunomodulatory properties of cardiac ATDPCs in anin vitroallostimulatory assay using allogeneic mature monocyte-derived dendritic cells (MDDCs). Similar to UCBMSCs, increasing amounts of seeded cardiac ATDPCs suppressed the alloproliferation of T cells in a dose-dependent manner. Secretion of proinflammatory cytokines (IL6, TNFα, and IFNγ) was also specifically modulated by the different numbers of cardiac ATDPCs cocultured. In summary, we show that cardiac ATDPCs abrogate T cell alloproliferation upon stimulation with allogeneic mature MDDCs, suggesting that they could further regulate a possible harmful immune responsein vivo. Additionally, UCBMSCs can be considered as valuable tools to preclinically predict the immunogenicity of prospective regenerative cells.

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