Precoating of biphasic calcium phosphate bone substitute with atelocollagen enhances bone regeneration through stimulation of osteoclast activation and angiogenesis

2017 ◽  
Vol 105 (5) ◽  
pp. 1446-1456 ◽  
Author(s):  
Beom-Su Kim ◽  
Sun-Sik Yang ◽  
Jun Lee
Author(s):  
Pluta Klaudia ◽  
Walczyk Dorota ◽  
Sobczak-Kupiec Agnieszka ◽  
Malina Dagmara ◽  
Tyliszczak Bozena

2019 ◽  
Vol 99 ◽  
pp. 1058-1066 ◽  
Author(s):  
Mirana Taz ◽  
Preeti Makkar ◽  
Khan Mohammad Imran ◽  
D.W. Jang ◽  
Yong-Sik Kim ◽  
...  

2007 ◽  
Vol 361-363 ◽  
pp. 119-122 ◽  
Author(s):  
J.H. Lim ◽  
J.H. Park ◽  
Eui Kyun Park ◽  
Hae Jung Kim ◽  
Il Kyu Park ◽  
...  

An appropriate scaffold, which provides structural support for transplanted cells and acts as a vehicle for the delivery of biologically active molecules, is critical for tissue engineering. We developed a fully interconnected globular porous biphasic calcium phosphate ceramic scaffold by adopting a foaming method, and evaluated its efficiency as a bone substitute and a scaffold for bone tissue engineering by in vitro and in vivo biocompatible analysis and its osteogenic healing capacity in rat tibial bone defects. They have spherical pores averaging 400um in diameter and interconnecting interpores averaging 70um in diameter with average 85% porosity. They elicited no cytotoxicity and noxious effect on cellular proliferation and osteoblastic differentiation during the cell-scaffold construct formation. Also the bone defects grafted with fully interconnected globular porous biphasic calcium phosphate ceramic blocks revealed excellent bone healing within 3 weeks. These findings suggest that the fully interconnected porous biphasic calcium phosphate scaffold formed by the foaming method can be a promising bone substitute and a scaffold for bone tissue engineering.


2019 ◽  
Vol 30 (S19) ◽  
pp. 183-183
Author(s):  
Nikola Matijević ◽  
Marija Pejakić ◽  
éeljka Perić Kačarević ◽  
Marko Matijević ◽  
Larisa Musić ◽  
...  

2015 ◽  
Vol 21 (11-12) ◽  
pp. 1822-1836 ◽  
Author(s):  
Mousumi Sukul ◽  
Thuy Ba Linh Nguyen ◽  
Young-Ki Min ◽  
Sun-Young Lee ◽  
Byong-Taek Lee

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