Gelatin/chondroitin sulfate nanofibrous scaffolds for stimulation of wound healing: In-vitro and in-vivo study

2017 ◽  
Vol 105 (7) ◽  
pp. 2020-2034 ◽  
Author(s):  
Mohamad Pezeshki-Modaress ◽  
Hamid Mirzadeh ◽  
Mojgan Zandi ◽  
Sareh Rajabi-Zeleti ◽  
Niloofar Sodeifi ◽  
...  
Keyword(s):  
Wound Healing ◽  
Chondroitin Sulfate ◽  
In Vivo Study ◽  
Nanofibrous Scaffolds ◽  
Stimulation Of Wound Healing ◽  
Stimulation Of

Enhanced wound healing by PVA/Chitosan/Curcumin patches: In vitro and in vivo study

2019 ◽  
Vol 182 ◽  
pp. 110339 ◽  
Author(s):  
Niranjan R. ◽  
Kaushik M. ◽  
Prakash J. ◽  
Venkataprasanna K.S. ◽  
Christy Arpana ◽  
...  
Keyword(s):  
Wound Healing ◽  
In Vivo Study

Silver Loaded Nanofibrous Curdlan Mat for Diabetic Wound Healing: An In Vitro and In Vivo Study

2018 ◽  
Vol 303 (9) ◽  
pp. 1800234 ◽  
Author(s):  
Rubaiya Yunus Basha ◽  
T. S. Sampath Kumar ◽  
Ramasamy Selvaraj ◽  
Mukesh Doble
Keyword(s):  
Wound Healing ◽  
In Vivo Study ◽  
Diabetic Wound ◽  
Diabetic Wound Healing

Fabrication and evaluation of chitosan/gelatin/PVA hydrogel incorporating honey for wound healing applications: An in vitro, in vivo study

2021 ◽  
Vol 592 ◽  
pp. 120068 ◽  
Author(s):  
Amir Shamloo ◽  
Zahra Aghababaie ◽  
Homa Afjoul ◽  
Mehrzad Jami ◽  
Mina Razaghzadeh Bidgoli ◽  
...  
Keyword(s):  
Wound Healing ◽  
In Vivo Study ◽  
Pva Hydrogel

scholarly journals Wound healing potential of human umbilical cord mesenchymal stem cell conditioned medium: An in vitro and in vivo study in diabetes-induced rats

2021 ◽  
pp. 2109-2117
Author(s):  
Siufui Hendrawan ◽  
Yuyus Kusnadi ◽  
Christine Ayu Lagonda ◽  
Dilafitria Fauza ◽  
Jennifer Lheman ◽  
...  
Keyword(s):  
Wound Healing ◽  
Animal Models ◽  
Conditioned Medium ◽  
Umbilical Cord ◽  
In Vivo Study ◽  
Human Umbilical Cord ◽  
Collagen Formation ◽  
Hypoxic Conditions

Background and Aim: Human umbilical cord mesenchymal stem cells (hUC-MSCs) and its conditioned medium (CM) promote wound healing. This study investigated the wound healing potential of hUC-MSC CM in vitro and in vivo using diabetic animal models. Materials and Methods: The CM from hUC-MSC CM prepared under hypoxic conditions (hypoxic hUC-MSC) was evaluated for stimulating rat fibroblast growth, collagen production (in vitro), and wound healing in animal models (in vivo). An excision wound on the dorsal side of the diabetes-induced rats was established, and the rats were randomly divided into non-treatment, antibiotic, and hypoxic hUC-MSC CM groups. The cell number of fibroblasts and collagen secretion was evaluated and compared among the groups in an in vitro study. By contrast, wound size reduction, width of re-epithelialization, and the collagen formation area were assessed and compared among the groups in an in vivo study. Results: CM under hypoxic conditions contained a higher concentration of wound healing-related growth factors. Hypoxic hUC-MSC CM could facilitate fibroblast cell growth and collagen synthesis, although not significant compared with the control group. Re-epithelialization and collagen production were higher in the hUC-MSC CM group than in the antibiotic and non-treatment groups. Conclusion: Hypoxic hUC-MSC CM possessed more positive effects on the wound healing process based on re-epithelialization and collagen formation than antibiotic treatment did.

scholarly journals Porous electrospun poly(ε-caprolactone)/gelatin nanofibrous mat containing cinnamon for wound healing application: in vitro and in vivo study

2019 ◽  
Vol 10 (1) ◽  
pp. 149-161 ◽  
Author(s):  
Majid Salehi ◽  
Maryam Niyakan ◽  
Arian Ehterami ◽  
Saeed Haghi-Daredeh ◽  
Simin Nazarnezhad ◽  
...  
Keyword(s):  
Wound Healing ◽  
In Vivo Study
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