Biodegradable polymer scaffolds loaded with low-dose BMP-2 stimulate periodontal ligament cell differentiation

2014 ◽  
Vol 103 (6) ◽  
pp. 1991-1998 ◽  
Author(s):  
Anders Skodje ◽  
Shaza Bushra M. Idris ◽  
Yang Sun ◽  
Sushma Bartaula ◽  
Kamal Mustafa ◽  
...  
Keyword(s):  
Cell Differentiation ◽  
Biodegradable Polymer ◽  
Periodontal Ligament ◽  
Low Dose ◽  
Polymer Scaffolds ◽  
Periodontal Ligament Cell

Role of Ascorbic Acid in Periodontal Ligament Cell Differentiation

2004 ◽  
Vol 75 (5) ◽  
pp. 709-716 ◽  
Author(s):  
Satoshi Ishikawa ◽  
Kengo Iwasaki ◽  
Motohiro Komaki ◽  
Isao Ishikawa
Keyword(s):  
Ascorbic Acid ◽  
Cell Differentiation ◽  
Periodontal Ligament ◽  
Periodontal Ligament Cell

YAP regulates periodontal ligament cell differentiation into myofibroblast interacted with RhoA/ROCK pathway

2018 ◽  
Vol 234 (4) ◽  
pp. 5086-5096 ◽  
Author(s):  
Yao He ◽  
Hui Xu ◽  
Zichao Xiang ◽  
Hongyou Yu ◽  
Li Xu ◽  
...  
Keyword(s):  
Cell Differentiation ◽  
Periodontal Ligament ◽  
Periodontal Ligament Cell

Effect of rhBMP-7 combined with two bone grafts on human periodontal ligament cell differentiation

2009 ◽  
Vol 27 (5) ◽  
pp. 274-279 ◽  
Author(s):  
X. E. Dereka ◽  
C. E. Markopoulou ◽  
A. Mamalis ◽  
I. A. Vrotsos
Keyword(s):  
Cell Differentiation ◽  
Periodontal Ligament ◽  
Bone Grafts ◽  
Periodontal Ligament Cell

N-Cadherin Expression During Periodontal Ligament Cell Differentiation In Vitro

1999 ◽  
Vol 70 (9) ◽  
pp. 1039-1045 ◽  
Author(s):  
Wen-Lang Lin ◽  
Hua-Hong Chien ◽  
Moon-Il Cho
Keyword(s):  
Cell Differentiation ◽  
Periodontal Ligament ◽  
Periodontal Ligament Cell

Response of Bone and Periodontal Ligament Cells to Biodegradable Polymer Scaffolds In Vitro

2010 ◽  
Vol 25 (6) ◽  
pp. 584-602 ◽  
Author(s):  
Kerstin Schander ◽  
Kristina Arvidson ◽  
Kamal Mustafa ◽  
Endre Hellem ◽  
Anne Isine Bolstad ◽  
...  
Keyword(s):  
Biodegradable Polymer ◽  
Periodontal Ligament ◽  
Periodontal Ligament Cells ◽  
Polymer Scaffolds

Enamel Matrix Derivative Promotes Human Periodontal Ligament Cell Differentiation and Osteoprotegerin Production in vitro

2007 ◽  
Vol 86 (10) ◽  
pp. 980-985 ◽  
Author(s):  
S. Lossdörfer ◽  
M. Sun ◽  
W. Götz ◽  
M. Dard ◽  
A. Jäger
Keyword(s):  
Cell Differentiation ◽  
Periodontal Ligament ◽  
Cell Number ◽  
Enamel Matrix Derivative ◽  
Periodontal Ligament Cells ◽  
Enamel Matrix ◽  
Periodontal Ligament Cell ◽  
Local Factor ◽  
Matrix Derivative

Enamel matrix derivative (EMD) has been used successfully to aid periodontal repair. We sought to elucidate the mechanism of action of EMD and hypothesized that combined exposure to EMD and parathyroid hormone (PTH), which acts anabolicly when administered intermittently, would enhance periodontal ligament cell proliferation, differentiation, and local factor production. Confluent human periodontal ligament cells were exposed to EMD continuously or to PTH(1-34) intermittently, or a combination of both. Cell number, alkaline phosphatase activity, osteocalcin, and osteoprotegerin production were determined. Continuous challenge with EMD resulted in an increase of the differentiation parameters and osteoprotegerin production, while simultaneously inhibiting proliferation. Intermittent PTH(1-34) administration exerted opposite effects. Combined administration of EMD and PTH(1-34) weakened or even nullified the effects seen for the agents alone. These results suggest that EMD promotes periodontal ligament cell differentiation and osteoprotegerin production, potentially resulting in a microenvironment supporting periodontal repair, whereas combining EMD and PTH(1-34) failed to prove beneficial in this respect.

scholarly journals Generation of biohybrid implants using a multipotent human periodontal ligament cell line and bioactive core materials

2021 ◽  
Author(s):  
Taiga Ono ◽  
Atsushi Tomokiyo ◽  
Keita Ipposhi ◽  
Kozue Yamashita ◽  
M Anas Alhasan ◽  
...  
Keyword(s):  
Cell Line ◽  
Periodontal Ligament ◽  
Periodontal Ligament Cell ◽  
Core Materials

Mitogenic Effects of Neurotrophins on a Periodontal Ligament Cell Line

2001 ◽  
Vol 80 (3) ◽  
pp. 881-886 ◽  
Author(s):  
Y. Tsuboi ◽  
T. Nakanishi ◽  
T. Takano-Yamamoto ◽  
M. Miyamoto ◽  
T. Yamashiro ◽  
...  
Keyword(s):  
Cell Line ◽  
Periodontal Ligament ◽  
Periodontal Ligament Cell
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