Hybrid hyaluronic acid hydrogel/poly(ɛ-caprolactone) scaffold provides mechanically favorable platform for cartilage tissue engineering studies

2013 ◽  
Vol 102 (9) ◽  
pp. 2918-2926 ◽  
Author(s):  
Benjamin R. Mintz ◽  
James A. Cooper
Keyword(s):  
Tissue Engineering ◽  
Hyaluronic Acid ◽  
Cartilage Tissue Engineering ◽  
Cartilage Tissue ◽  
Engineering Studies ◽  
Hyaluronic Acid Hydrogel

scholarly journals An injectable, click-crosslinked, cytomodulin-modified hyaluronic acid hydrogel for cartilage tissue engineering

2019 ◽  
Vol 11 (1) ◽  
Author(s):  
Seung Hun Park ◽  
Ji Young Seo ◽  
Joon Yeong Park ◽  
Yun Bae Ji ◽  
Kyungsook Kim ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Hyaluronic Acid ◽  
Cartilage Tissue Engineering ◽  
Cartilage Tissue ◽  
Hyaluronic Acid Hydrogel

scholarly journals Digital Light Processing Bioprinted Human Chondrocyte-Laden Poly (γ-Glutamic Acid)/Hyaluronic Acid Bio-Ink towards Cartilage Tissue Engineering

Biomedicines ◽  
2021 ◽  
Vol 9 (7) ◽  
pp. 714
Author(s):  
Alvin Kai-Xing Lee ◽  
Yen-Hong Lin ◽  
Chun-Hao Tsai ◽  
Wan-Ting Chang ◽  
Tsung-Li Lin ◽  
...  
Keyword(s):  
United States ◽  
Tissue Engineering ◽  
Hyaluronic Acid ◽  
Glutamic Acid ◽  
Cellular Proliferation ◽  
Cartilage Tissue Engineering ◽  
Cartilage Regeneration ◽  
The United States ◽  
Cartilage Injury ◽  
Cartilage Tissue

Cartilage injury is the main cause of disability in the United States, and it has been projected that cartilage injury caused by osteoarthritis will affect 30% of the entire United States population by the year 2030. In this study, we modified hyaluronic acid (HA) with γ-poly(glutamic) acid (γ-PGA), both of which are common biomaterials used in cartilage engineering, in an attempt to evaluate them for their potential in promoting cartilage regeneration. As seen from the results, γ-PGA-GMA and HA, with glycidyl methacrylate (GMA) as the photo-crosslinker, could be successfully fabricated while retaining the structural characteristics of γ-PGA and HA. In addition, the storage moduli and loss moduli of the hydrogels were consistent throughout the curing durations. However, it was noted that the modification enhanced the mechanical properties, the swelling equilibrium rate, and cellular proliferation, and significantly improved secretion of cartilage regeneration-related proteins such as glycosaminoglycan (GAG) and type II collagen (Col II). The cartilage tissue proof with Alcian blue further demonstrated that the modification of γ-PGA with HA exhibited suitability for cartilage tissue regeneration and displayed potential for future cartilage tissue engineering applications. This study built on the previous works involving HA and further showed that there are unlimited ways to modify various biomaterials in order to further bring cartilage tissue engineering to the next level.

scholarly journals Correction: An injectable hyaluronic acid/PEG hydrogel for cartilage tissue engineering formed by integrating enzymatic crosslinking and Diels–Alder “click chemistry”

2018 ◽  
Vol 9 (28) ◽  
pp. 3959-3960 ◽  
Author(s):  
Feng Yu ◽  
Xiaodong Cao ◽  
Yuli Li ◽  
Lei Zeng ◽  
Bo Yuan ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Hyaluronic Acid ◽  
Click Chemistry ◽  
Cartilage Tissue Engineering ◽  
Diels Alder ◽  
Cartilage Tissue

Correction for ‘An injectable hyaluronic acid/PEG hydrogel for cartilage tissue engineering formed by integrating enzymatic crosslinking and Diels–Alder “click chemistry”’ by Feng Yu et al., Polym. Chem., 2014, 5, 1082–1090.

Enzymatically-crosslinked injectable hydrogels based on biomimetic dextran–hyaluronic acid conjugates for cartilage tissue engineering

Biomaterials ◽  
2010 ◽  
Vol 31 (11) ◽  
pp. 3103-3113 ◽  
Author(s):  
R. Jin ◽  
L.S. Moreira Teixeira ◽  
P.J. Dijkstra ◽  
C.A. van Blitterswijk ◽  
M. Karperien ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Hyaluronic Acid ◽  
Cartilage Tissue Engineering ◽  
Cartilage Tissue ◽  
Injectable Hydrogels

scholarly journals A biomimetic extracellular matrix for cartilage tissue engineering centered on photocurable gelatin, hyaluronic acid and chondroitin sulfate

2014 ◽  
Vol 10 (1) ◽  
pp. 214-223 ◽  
Author(s):  
Peter A. Levett ◽  
Ferry P.W. Melchels ◽  
Karsten Schrobback ◽  
Dietmar W. Hutmacher ◽  
Jos Malda ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Extracellular Matrix ◽  
Hyaluronic Acid ◽  
Chondroitin Sulfate ◽  
Cartilage Tissue Engineering ◽  
Cartilage Tissue

scholarly journals Chitosan Scaffolds Containing Hyaluronic Acid for Cartilage Tissue Engineering

2011 ◽  
Vol 17 (7) ◽  
pp. 717-730 ◽  
Author(s):  
Clara R. Correia ◽  
Liliana S. Moreira-Teixeira ◽  
Lorenzo Moroni ◽  
Rui L. Reis ◽  
Clemens A. van Blitterswijk ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Hyaluronic Acid ◽  
Cartilage Tissue Engineering ◽  
Cartilage Tissue ◽  
Chitosan Scaffolds

scholarly journals Chitosan Scaffolds Containing Hyaluronic Acid for Cartilage Tissue Engineering

2011 ◽  
pp. 110308075242061
Author(s):  
Clara Correia ◽  
Liliana S MoreiraTeixeira ◽  
Lorenzo Moroni ◽  
Rui L. Reis ◽  
Clemens van Blitterswijk ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Hyaluronic Acid ◽  
Cartilage Tissue Engineering ◽  
Cartilage Tissue ◽  
Chitosan Scaffolds
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