The effect of plasma-nitrided titanium surfaces on osteoblastic cell adhesion, proliferation, and differentiation

2013 ◽  
Vol 102 (4) ◽  
pp. 991-998 ◽  
Author(s):  
Emanuela P. Ferraz ◽  
Juliana C. Sa ◽  
Paulo T. de Oliveira ◽  
Clodomiro Alves ◽  
Marcio M. Beloti ◽  
...  
2014 ◽  
Vol 28 (12) ◽  
pp. 1207-1218 ◽  
Author(s):  
Miguel A. Fernández-Rodríguez ◽  
Alda Y. Sánchez-Treviño ◽  
Elvira De Luna-Bertos ◽  
Javier Ramos-Torrecillas ◽  
Olga García-Martínez ◽  
...  

RSC Advances ◽  
2015 ◽  
Vol 5 (99) ◽  
pp. 81378-81387 ◽  
Author(s):  
Ting Ma ◽  
Xi-Yuan Ge ◽  
Sheng-Nan Jia ◽  
Xi Jiang ◽  
Yu Zhang ◽  
...  

The effect of alkali-treated titanium surfaces on inflammation-related gene expression of macrophages and alkaline phosphatase activity of osteoblast-like cells.


2008 ◽  
Vol 1136 ◽  
Author(s):  
Jing Lu ◽  
Dongwoo Khang ◽  
Thomas J. Webster

ABSTRACTTo study the contribution of different surface feature properties in improving vascular endothelial cell adhesion, rationally designed nano/sub-micron patterns with various dimensions were created on titanium surfaces in this study. In vitro results indicated that endothelial cell adhesion was improved when the titanium pattern dimensions decreased into the nano-scale. Specifically, endothelial cells preferred to adhere on sub-micron and nano rough titanium substrates compared to flat titanium. Moreover, titanium with nano and sub-micron roughness and with the same chemistry as compared to flat titanium, had significantly greater surface energy. Thus, the present study indicated the strong potential of surface nanotopography and nano/sub-micron roughness for improving current vascular stent design.


2020 ◽  
Vol Volume 15 ◽  
pp. 5061-5072
Author(s):  
Lu Sun ◽  
Guang Hong ◽  
Hiroyuki Matsui ◽  
Yun-Jia Song ◽  
Keiichi Sasaki

2009 ◽  
Vol 24 (3) ◽  
pp. 200-205 ◽  
Author(s):  
Taís Somacal Novaes Silva ◽  
Denise Cantarelli Machado ◽  
Christian Viezzer ◽  
Aurelício Novaes Silva Júnior ◽  
Marília Gerhardt de Oliveira

PURPOSE: To assess the proliferation and differentiation of human bone marrow-derived cells cultured on titanium surfaces with different roughness characteristics. METHODS: Cells obtained from the iliac crest of an adult human donor were routinely processed and cultured on titanium surfaces of varying roughness, according to their preparation method: polishing only (smooth surface) and polishing followed by etching with HF/HNO3 for 15 and 30 minutes (rough surfaces). Surfaces were assessed using scanning electronic microscopy and profilometry. RESULTS: Titanium disks etched with acid for 15 minutes allowed greater cell proliferation in all culture periods. The level of osteopontin and osteocalcin expression was increased in both acid-etched groups, which indicates an advanced stage of differentiation of cells into osteoblasts. CONCLUSIONS: Increased surface roughness accelerates the differentiation of undifferentiated mesenchymal cells into osteogenic lineage cells, but does not necessarily favor cell proliferation. An intermediate surface roughness of 0.5µm (acid etching for 15 minutes) favors both initial and final cell responses.


2015 ◽  
Vol 3 (44) ◽  
pp. 8738-8746 ◽  
Author(s):  
R. Toita ◽  
Sunarso Sunarso ◽  
A. N. Rashid ◽  
K. Tsuru ◽  
K. Ishikawa

A Ca-modified PEEK facilitates osteoblastic cell proliferation and differentiation and shifts macrophage phenotype towards anti-inflammatory/wound healing type.


2012 ◽  
Vol 32 (3) ◽  
pp. 241-269 ◽  
Author(s):  
Suet-Mien Tan

Leucocytes are highly motile cells. Their ability to migrate into tissues and organs is dependent on cell adhesion molecules. The integrins are a family of heterodimeric transmembrane cell adhesion molecules that are also signalling receptors. They are involved in many biological processes, including the development of metazoans, immunity, haemostasis, wound healing and cell survival, proliferation and differentiation. The leucocyte-restricted β2 integrins comprise four members, namely αLβ2, αMβ2, αXβ2 and αDβ2, which are required for a functional immune system. In this paper, the structure, functional regulation and signalling properties of these integrins are reviewed.


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