In vivo NIR imaging with PbS quantum dots entrapped in biodegradable micelles

2012 ◽  
Vol 100A (4) ◽  
pp. 958-968 ◽  
Author(s):  
Jie Cao ◽  
Hongyan Zhu ◽  
Dawei Deng ◽  
Bing Xue ◽  
Liping Tang ◽  
...  
Theranostics ◽  
2012 ◽  
Vol 2 (7) ◽  
pp. 723-733 ◽  
Author(s):  
Rui Hu ◽  
Wing-Cheung Law ◽  
Guimiao Lin ◽  
Ling Ye ◽  
Jianwei Liu ◽  
...  

Nano Research ◽  
2020 ◽  
Vol 13 (8) ◽  
pp. 2239-2245 ◽  
Author(s):  
Xiulei Shi ◽  
Song Chen ◽  
Meng-Yao Luo ◽  
Biao Huang ◽  
Guozhen Zhang ◽  
...  

2016 ◽  
Vol 52 (21) ◽  
pp. 4025-4028 ◽  
Author(s):  
Jun Chen ◽  
Yifei Kong ◽  
Wei Wang ◽  
Hongwei Fang ◽  
Yan Wo ◽  
...  

LG capped PbS quantum dots: a highly water-dispersible and biocompatible image reporter in the second near-infrared window.


2021 ◽  
Author(s):  
Alexander M. Saeboe ◽  
Alexey Y. Nikiforov ◽  
Reyhaneh Toufanian ◽  
Joshua C. Kays ◽  
Margaret Chern ◽  
...  

AbstractThis report of the reddest emitting indium phosphide quantum dots (InP QDs) to date demonstrates tunable, near infrared (NIR) photoluminescence and fluorescence multiplexing in the first optical tissue window with a material that avoids toxic constituents. This synthesis overcomes the InP synthesis “growth bottleneck” and extends the emission peak of InP QDs deeper into the first optical tissue window using an inverted QD heterostructure. The ZnSe/InP/ZnS core/shell/shell structure is designed to produce emission from excitons with heavy holes confined in InP shells wrapped around larger-bandgap ZnSe cores and protected by a second shell of ZnS. The InP QDs exhibit InP shell thickness-dependent tunable emission with peaks ranging from 515 – 845 nm. The high absorptivity of InP leads to effective absorbance and photoexcitation of the QDs with UV, visible, and NIR wavelengths in particles with diameters of eight nanometers or less. These nanoparticles extend the range of tunable direct-bandgap emission from InP-based nanostructures, effectively overcoming a synthetic barrier that has prevented InP-based QDs from reaching their full potential as NIR imaging agents. Multiplexed lymph node imaging in a mouse model shows the potential of the NIR-emitting InP particles for in vivo imaging.


Nanoscale ◽  
2015 ◽  
Vol 7 (12) ◽  
pp. 5115-5119 ◽  
Author(s):  
Akira Sasaki ◽  
Yoshikazu Tsukasaki ◽  
Akihito Komatsuzaki ◽  
Takao Sakata ◽  
Hidehiro Yasuda ◽  
...  

We report a one-step synthetic strategy for the preparation of recombinant protein (EGFP-Protein G)-coated PbS quantum dots for dual (visible and second-NIR) fluorescence imaging of breast tumors.


Molecules ◽  
2016 ◽  
Vol 21 (8) ◽  
pp. 1080 ◽  
Author(s):  
Yukio Imamura ◽  
Sayumi Yamada ◽  
Setsuko Tsuboi ◽  
Yuko Nakane ◽  
Yoshikazu Tsukasaki ◽  
...  

2011 ◽  
Vol 353 (2) ◽  
pp. 363-371 ◽  
Author(s):  
Jin Soo Kim ◽  
Kwang Jae Cho ◽  
Thanh Huyen Tran ◽  
Md. Nurunnabi ◽  
Tae Hyun Moon ◽  
...  

2020 ◽  
Author(s):  
Iván Mora-Seró ◽  
Sofia Masi ◽  
David Macias-Pinilla ◽  
Carlos Echeverría-Arrondo ◽  
Juan Ignacio Climente

2020 ◽  
Vol 26 (18) ◽  
pp. 2167-2181
Author(s):  
Tatielle do Nascimento ◽  
Melanie Tavares ◽  
Mariana S.S.B. Monteiro ◽  
Ralph Santos-Oliveira ◽  
Adriane R. Todeschini ◽  
...  

Background: Cancer is a set of diseases formed by abnormal growth of cells leading to the formation of the tumor. The diagnosis can be made through symptoms’ evaluation or imaging tests, however, the techniques are limited and the tumor detection may be late. Thus, pharmaceutical nanotechnology has emerged to optimize the cancer diagnosis through nanostructured contrast agent’s development. Objective: This review aims to identify commercialized nanomedicines and patents for cancer diagnosis. Methods: The databases used for scientific articles research were Pubmed, Science Direct, Scielo and Lilacs. Research on companies’ websites and articles for the recognition of commercial nanomedicines was performed. The Derwent tool was applied for patent research. Results: This article aimed to research on nanosystems based on nanoparticles, dendrimers, liposomes, composites and quantum dots, associated to imaging techniques. Commercialized products based on metal and composite nanoparticles, associated with magnetic resonance and computed tomography, have been observed. The research conducted through Derwent tool displayed a small number of patents using nanotechnology for cancer diagnosis. Among these patents, the most significant number was related to the use of systems based on metal nanoparticles, composites and quantum dots. Conclusion: Although few systems are found in the market and patented, nanotechnology appears as a promising field for the development of new nanosystems in order to optimize and accelerate the cancer diagnosis.


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