Amidine surface modification of poly(acrylonitrile-co-vinyl chloride) reduces platelet adhesion

2009 ◽  
Vol 89A (3) ◽  
pp. 780-790 ◽  
Author(s):  
Evelyn K. F. Yim ◽  
Michael V. Sefton
2008 ◽  
Vol 61 (6) ◽  
pp. 446 ◽  
Author(s):  
Ai-Fu Che ◽  
Xiao-Jun Huang ◽  
Zhen-Gang Wang ◽  
Zhi-Kang Xu

Poly(acrylonitrile-co-acrylic acid) (PANCAA) was synthesized and fabricated into nanofibrous membranes by an electrospinning technique. Scanning electron microscopy revealed that membranes composed of uniformly thin and smooth nanofibres were obtained under optimized processing parameters. Surface modification with chitosan on these nanofibrous membranes was accomplished by a coupling reaction between the carboxylic groups of PANCAA and the primary amino groups of chitosan. Fluorescent labelling, weight measurement, FT-IR/ATR spectroscopy, and X-ray photoelectron spectroscopy (XPS) were used to confirm the modification process and determine the immobilization degree of chitosan. Platelet adhesion experiments were further carried out to evaluate the hemocompatibility of the studied nanofibrous membranes. Preliminary results indicated that the immobilization of chitosan on the PANCAA nanofibrous membranes was favourable for platelet adhesion.


Author(s):  
Marcelo Munoz ◽  
Antony El-khoury ◽  
Cagla Eren Cimenci ◽  
Mayte Gonzalez-Gomez ◽  
Robert A. Hunter ◽  
...  

2008 ◽  
Vol 110 (1) ◽  
pp. 39-48 ◽  
Author(s):  
E Zhao ◽  
Lian Wang ◽  
Lifeng Yan ◽  
Yoshifumi Torimoto ◽  
Quanxin Li

2011 ◽  
Vol 12 (12) ◽  
pp. 4348-4356 ◽  
Author(s):  
Wei-Hsuan Kuo ◽  
Meng-Jiy Wang ◽  
Hsiu-Wen Chien ◽  
Ta-Chin Wei ◽  
Chiapyng Lee ◽  
...  

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