Substance P augments PGE2 and IL-6 production in titanium particles-stimulated fibroblasts from hip periprosthetic membrane

2007 ◽  
Vol 83A (2) ◽  
pp. 401-406 ◽  
Author(s):  
Yebin Qian ◽  
Bing-Fang Zeng ◽  
Xian-long Zhang ◽  
Yao Jiang
Keyword(s):  
Substance P ◽  
Periprosthetic Membrane

Substance P enhanced titanium particles-induced RANKL expression in fibroblasts from periprosthetic membrane

2013 ◽  
Vol 54 (6) ◽  
pp. 361-366 ◽  
Author(s):  
Yebin Qian ◽  
Xian-long Zhang ◽  
Bing-Fang Zeng ◽  
Yao Jiang ◽  
Hao Shen ◽  
...  
Keyword(s):  
Substance P ◽  
Rankl Expression ◽  
Periprosthetic Membrane

Mast cell-nerve fiber interaction: Ultrastructural studies

1990 ◽  
Vol 48 (3) ◽  
pp. 428-429
Author(s):  
E.Y. Chi ◽  
M.L. Su ◽  
Y.T. Tien ◽  
W.R. Henderson
Keyword(s):  
Mast Cell ◽  
Mast Cells ◽  
Substance P ◽  
Nerve Fiber ◽  
Sensory Nerves ◽  
Ultrastructural Studies ◽  
Morphological Studies ◽  
Granulocyte Infiltration ◽  
Intracutaneous Injection ◽  
Recent Attention

Recent attention has been directed to the interaction of the nerve and immune systems. The neuropeptide substance P, a tachykinnin which is a neurotransmitter in the central and peripheral nervous systems produces tissue swelling, augemntation of intersitial fibrin deposition and leukocyte infiltration after intracutaneous injection. There is a direct correlation reported between the extent of mast cell degranulation at the sites of injection and the tissue swelling or granulocyte infiltration. It has previously been demonstrated that antidromic electrical stimulation of sensory nerves induces degranulation of cutaneous mast cells, cutaneous vasodilation and augmented vascular permeability. Morphological studies have documented a close anatiomical association between mast cells and nonmyelinated nerves, that contain substance P and other neuropeptides. However, the presence of mast cells within nerve fasicles has not been previously examined ultrastructurally. In this study, we examined ultrastructurally the distribution of mast cells in the nerve fiber bundles located in the muscular connective tissue of rat tongues (n=20).

Elevated levels of substance P in tears of patients with allergic conjunctivitis and vernal keratoconjunctivitis

1997 ◽  
Vol 27 (4) ◽  
pp. 372-378 ◽  
Author(s):  
H. FUJISHIMA ◽  
M. TAKEYAMA ◽  
T. TAKEUCHI ◽  
I. SAITO ◽  
K. TSUBOTA
Keyword(s):  
Substance P ◽  
Allergic Conjunctivitis ◽  
Vernal Keratoconjunctivitis
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