Handbook of bioactive ceramics. vol. 1, bioactive glasses and glass-ceramics and vol. 2, calcium phosphate and hydroxylapatite ceramics. T. Yamamuro L. Hench J. Wilson CRC Press, Boca Raton, FL, 1990.

1991 ◽  
Vol 25 (7) ◽  
pp. 903-904 ◽  
Author(s):  
Jack E. Lemons
2007 ◽  
Vol 361-363 ◽  
pp. 229-232 ◽  
Author(s):  
Marcelo Henrique Prado da Silva ◽  
C. Moura Ramirez ◽  
José Mauro Granjeiro ◽  
Antonella M. Rossi

Niobo-phosphate glasses were produced in order to assess the citotoxicity of samples with different compositions. Different P2O5/Ca ratios were studied in an attempt to correlate the biological behavior of new niobo-phosphate bioactive glasses with conventional bioactive calcium phosphate glasses. The most biocompatible glass composition was chosen to produce glassreinforced hydroxyapatite composites.


1987 ◽  
Vol 95 (1104) ◽  
pp. 785-791 ◽  
Author(s):  
Takashi KOKUBO ◽  
Tetsuya HAYASHI ◽  
Sumio SAKKA ◽  
Toshiaki KITSUGI ◽  
Takashi YAMAMURO

Author(s):  
Seong Ho Choi ◽  
D.H. Baik ◽  
C.S. Kim ◽  
Chong Kwan Kim ◽  
Kyoung Nam Kim ◽  
...  

2010 ◽  
Vol 30 (12) ◽  
pp. 2563-2567 ◽  
Author(s):  
Christian Bergmann ◽  
Markus Lindner ◽  
Wen Zhang ◽  
Karolina Koczur ◽  
Armin Kirsten ◽  
...  

2019 ◽  
Vol 10 (3) ◽  
pp. 38 ◽  
Author(s):  
Hamasa Faqhiri ◽  
Markus Hannula ◽  
Minna Kellomäki ◽  
Maria Teresa Calejo ◽  
Jonathan Massera

This study reports on the processing of three-dimensional (3D) chitosan/bioactive glass composite scaffolds. On the one hand, chitosan, as a natural polymer, has suitable properties for tissue engineering applications but lacks bioactivity. On the other hand, bioactive glasses are known to be bioactive and to promote a higher level of bone formation than any other biomaterial type. However, bioactive glasses are hard, brittle, and cannot be shaped easily. Therefore, in the past years, researchers have focused on the processing of new composites. Difficulties in reaching composite materials made of polymer (synthetic or natural) and bioactive glass include: (i) The high glass density, often resulting in glass segregation, and (ii) the fast bioactive glass reaction when exposed to moisture, leading to changes in the glass reactivity and/or change in the polymeric matrix. Samples were prepared with 5, 15, and 30 wt% of bioactive glass S53P4 (BonAlive ®), as confirmed using thermogravimetric analysis. MicrO–Computed tomography and optical microscopy revealed a flaky structure with porosity over 80%. The pore size decreased when increasing the glass content up to 15 wt%, but increased back when the glass content was 30 wt%. Similarly, the mechanical properties (in compression) of the scaffolds increased for glass content up to 15%, but decreased at higher loading. Ions released from the scaffolds were found to lead to precipitation of a calcium phosphate reactive layer at the scaffold surface. This is a first indication of the potential bioactivity of these materials. Overall, chitosan/bioactive glass composite scaffolds were successfully produced with pore size, machinability, and ability to promote a calcium phosphate layer, showing promise for bone tissue engineering and the mechanical properties can justify their use in non-load bearing applications.


2000 ◽  
Vol 192-195 ◽  
pp. 223-226 ◽  
Author(s):  
Toshihiro Kasuga ◽  
Masayuki Nogami ◽  
Mitsuo Niinomi

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