Use of organ cultures to evaluate biodegradation of polymer implant materials

1973 ◽  
Vol 7 (2) ◽  
pp. 205-214 ◽  
Author(s):  
Andrew F. Hegyeli
1977 ◽  
Vol 37 (1) ◽  
pp. 74-82 ◽  
Author(s):  
Lawrence Gettleman ◽  
Dan Nathanson ◽  
Richard L. Myerson

2018 ◽  
Vol 40 (1) ◽  
pp. 1800611 ◽  
Author(s):  
Rainhard Machatschek ◽  
Burkhard Schulz ◽  
Andreas Lendlein

1971 ◽  
Vol 50 (6) ◽  
pp. 1631-1634 ◽  
Author(s):  
Milton Hodosh ◽  
Gerald Shklar ◽  
Morris Povar

The topography of the surface of a variety of polymer mixtures was studied. Large porosities were found in various mixtures of methacrylate polymer powder, anorganic bone, and a foaming agent, N, N' -dinitrosopentamethylenetetramine. The porosities appeared to be linked by smaller spaces and channels that ran through the polymer material. The porosity of the polymer was altered significantly by materials such as anorganic bone or foaming agents, but the composition by percentage did not alter the material structure appreciably.


2020 ◽  
Vol 53 (6) ◽  
pp. 429-432 ◽  
Author(s):  
T. I. Karpunina ◽  
A. P. Godovalov ◽  
D. E. Yakusheva

Author(s):  
Bruce Wetzel ◽  
Robert Buscho ◽  
Raphael Dolin

It has been reported that explants of human fetal intestine can be maintained in culture for up to 21 days in a viable condition and that these organ cultures support the growth of a variety of known viral agents responsible for enteric disease. Scanning electron microscopy (SEM) has been undertaken on several series of these explants to determine their appearance under routine culture conditions.Fresh specimens of jejunum obtained from normal human fetuses were washed, dissected into l-4mm pieces, and cultured in modified Leibowitz L-15 medium at 34° C as previously described. Serial specimens were fixed each day in 3% glutaraldehyde for 90 minutes at room temperature, rinsed, dehydrated, and dried by the CO2 critical point method in a Denton DCP-1 device. Specimens were attached to aluminum stubs with 3M transfer tape No. 465, and one sample on each stub was carefully rolled along the adhesive such that villi were broken off to expose their interiors.


1991 ◽  
Vol 4 (02) ◽  
pp. 38-45 ◽  
Author(s):  
F. Baumgart

SummaryThe so-called “mixing” of implants and instruments from different producers entertain certain risks.The use of standardized implant materials (e.g. stainless steel ISO 5832/1) from different producers is necessary but is not sufficient to justify the use of an osteosynthesis plate from one source and a bone screw from another.The design, dimensions, tolerances, manufacturing procedure, quality controls, and application technique of the instruments and implants also vary according to make. This can lead to damage, failure or fracture of the biomechanical system called “osteosynthesis” and hence the failure of the treatment undertaken. In the end, it is the patient who pays for these problems.Some examples also illustrate the potential problems for the staff and institutions involved.The use of a unique, consistent, well-tested, and approved set of implants and instruments is to be strongly recommended to avoid any additional risk.


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