Kinetic study of citric acid influence on calcium phosphate bone cements as water-reducing agent

2002 ◽  
Vol 61 (4) ◽  
pp. 653-659 ◽  
Author(s):  
S. Sarda ◽  
E. Fernández ◽  
M. Nilsson ◽  
M. Balcells ◽  
J. A. Planell
Author(s):  
Denton D. Weiss ◽  
Matthew A. Sachs ◽  
Charles R. Woodard

2021 ◽  
Vol 5 (1) ◽  
pp. 30
Author(s):  
Angelica Bertacci ◽  
Daniele Moro ◽  
Gianfranco Ulian ◽  
Giovanni Valdrè

Recently, endodontic sealers based on injectable bioactive materials were proposed to improve the filling of anatomical irregularities during root canal obturation. In this context, this preliminary work investigated the possibility of realizing a new calcium phosphate-based composite sealer for root canal filling with an optimized composition on setting kinetics and dentin tubules occlusion. Several calcium phosphate/liquid phase mixtures were initially evaluated for their workability, finding two suitable formulations. Both of them contained 66 wt.% of a nano-apatite-based cement (solid powdered phase). The liquid phase (34 wt.%) comprised 13.6% propanediol and 20.4% PEG 1000 (formulation 1), and formulation 2 comprised 27.2% glycerin and 6.8% PEG 200 (formulation 2). Then, these formulations were tested by means of permeability measurements and observation by scanning electron microscopy of treated model dentin samples. Both formulations succeeded in occluding dentinal tubules: the first one was able to create a full-bodied layer on dentin surface and, moreover, to resist, at least to a large extent, against citric acid attack. The second one showed a lower effectiveness after citric acid exposure. The composite compound that better satisfied the overall required characteristics of use, workability and sealing capacity was formulation 1.


Author(s):  
Yu Qu ◽  
Hui Zhuang ◽  
Meng Zhang ◽  
Yufeng Wang ◽  
Dong Zhai ◽  
...  

Although calcium phosphate cements (CPC) have been clinically used to repair bone defects caused by bone tumor resection, traditional CPC cannot kill the remaining tumor cells after surgery and prevent...


2019 ◽  
Vol 45 (4) ◽  
pp. 147-157 ◽  
Author(s):  
Daiki Azuma ◽  
Tatsuya Aikawa ◽  
Yuya Hiraga ◽  
Masaru Watanabe ◽  
Richard Lee Smith Jr.

ACS Omega ◽  
2017 ◽  
Vol 2 (8) ◽  
pp. 5196-5208 ◽  
Author(s):  
Regina C. So ◽  
Jemimah E. Sanggo ◽  
Lei Jin ◽  
Jose Mario A. Diaz ◽  
Raphael A. Guerrero ◽  
...  

Author(s):  
Coathup Melanie ◽  
Kent Niall ◽  
Hill Robert ◽  
Ferro De Godoy Roberta ◽  
Quak Wenyu ◽  
...  

Author(s):  
Nuan La Ong Srakaew ◽  
Sirirat Tubsungnoen Rattanachan

Self-setting calcium phosphate cement (CPC) has been used in bone repair and substitution due to their excellent biocompatibility, bioactive as well as simplicity of preparation and use. The inherent brittleness and slow degradation are the major disadvantages for the use of calcium phosphate cements. To improve the degradation for the traditional CPC, the apatite cement formula incorporated with β-tricalcium phosphate (β-TCP) with varying concentration were studied and the effect of the pH value of liquid phase on the properties of this new calcium phosphate cement formula was evaluated. The apatite cements containing β-TCP for 10 and 40 wt.% were mixed into the aqueous solution with different pH values and then aging in absolute humidity at 37°C for 7 days. The setting time and phase analysis of the biphasic calcium phosphate were determined as compared to the apatite cement. For proper medical application, the compressive strength, the phase analysis and the degradation of the CPC samples at pH 7.0 and 7.4 were evaluated after soaking in the simulated body fluid (SBF) at 37°C for 7 days. The results indicated that the properties of the samples such as the setting time, the compressive strength related to the phase analysis of the set cements. The high degradation of the CPC was found in the cement with increasing β-TCP addition due to the phase after setting. Apatite formation with oriented plate-like morphology was also found to be denser on the surface of the biphasic bone cements after soaking in SBF for 7 days. The obtained results indicated that the cement containing β-TCP mixed with the liquid phase at pH 7.4 could be considered as a highly biodegradable and bioactive bone cement, as compared to the traditional CPC.


2018 ◽  
Vol 17 (2) ◽  
pp. e439-e440
Author(s):  
S. Doizi ◽  
J. Poindexter ◽  
M. Pearle ◽  
K. Sakhaee ◽  
N. Maalouf

2020 ◽  
Vol 9 (3) ◽  
pp. 155-163
Author(s):  
Esra Güben ◽  
Şule Arıcı ◽  
Dilara Bayır ◽  
Ergün Bozdağ ◽  
Duygu Ege

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