Prognostic analysis of amyotrophic lateral sclerosis based on clinical features and plasma surface‐enhanced Raman spectroscopy

2019 ◽  
Vol 12 (8) ◽  
Author(s):  
Qi‐Jie Zhang ◽  
Yang Chen ◽  
Xiao‐Huan Zou ◽  
Wei Hu ◽  
Xue‐Liang Lin ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Amyotrophic Lateral Sclerosis ◽  
Clinical Features ◽  
Surface Enhanced Raman Spectroscopy ◽  
Plasma Surface ◽  
Prognostic Analysis ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Lateral Sclerosis

Blood plasma surface-enhanced Raman spectroscopy for non-invasive optical detection of cervical cancer

The Analyst ◽  
2013 ◽  
Vol 138 (14) ◽  
pp. 3967 ◽  
Author(s):  
Shangyuan Feng ◽  
Duo Lin ◽  
Juqiang Lin ◽  
Buhong Li ◽  
Zufang Huang ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Raman Spectroscopy ◽  
Blood Plasma ◽  
Optical Detection ◽  
Surface Enhanced Raman Spectroscopy ◽  
Plasma Surface ◽  
Non Invasive ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

Bacterial detection and differentiation via direct volatile organic compound sensing with surface enhanced Raman spectroscopy

2017 ◽  
Author(s):  
Caitlin S. DeJong ◽  
David I. Wang ◽  
Aleksandr Polyakov ◽  
Anita Rogacs ◽  
Steven J. Simske ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Bacterial Infections ◽  
Direct Detection ◽  
Point Of Care ◽  
Surface Enhanced Raman Spectroscopy ◽  
E Coli ◽  
Recent Emergence ◽  
Surface Enhanced ◽  
Volatile Organic ◽  
Surface Enhanced Raman

Through the direct detection of bacterial volatile organic compounds (VOCs), via surface enhanced Raman spectroscopy (SERS), we report here a reconfigurable assay for the identification and monitoring of bacteria. We demonstrate differentiation between highly clinically relevant organisms: <i>Escherichia coli</i>, <i>Enterobacter cloacae</i>, and <i>Serratia marcescens</i>. This is the first differentiation of bacteria via SERS of bacterial VOC signatures. The assay also detected as few as 10 CFU/ml of <i>E. coli</i> in under 12 hrs, and detected <i>E. coli</i> from whole human blood and human urine in 16 hrs at clinically relevant concentrations of 10<sup>3</sup> CFU/ml and 10<sup>4</sup> CFU/ml, respectively. In addition, the recent emergence of portable Raman spectrometers uniquely allows SERS to bring VOC detection to point-of-care settings for diagnosing bacterial infections.

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