Confocal Raman microspectroscopy on excised human skin: uncertainties in depth profiling and mathematical correction applied to dermatological drug permeation

2008 ◽  
Vol 1 (2) ◽  
pp. 140-153 ◽  
Author(s):  
A. Tfayli ◽  
O. Piot ◽  
M. Manfait
Keyword(s):  
Human Skin ◽  
Depth Profiling ◽  
Raman Microspectroscopy ◽  
Drug Permeation ◽  
Confocal Raman Microspectroscopy ◽  
Confocal Raman

Correction of optical distortions in dry depth profiling with confocal Raman microspectroscopy

2011 ◽  
Vol 42 (6) ◽  
pp. 1330-1334 ◽  
Author(s):  
J. Pablo Tomba ◽  
María de la Paz Miguel ◽  
Claudio J. Perez
Keyword(s):  
Depth Profiling ◽  
Raman Microspectroscopy ◽  
Confocal Raman Microspectroscopy ◽  
Confocal Raman

scholarly journals Correction: Confocal Raman microspectroscopy for skin characterization: a comparative study between human skin and pig skin

The Analyst ◽  
2020 ◽  
Vol 145 (13) ◽  
pp. 4699-4700
Author(s):  
Sana Tfaili ◽  
Cyril Gobinet ◽  
Gwendal Josse ◽  
Jean-François Angiboust ◽  
Michel Manfait ◽  
...  
Keyword(s):  
Comparative Study ◽  
Human Skin ◽  
Raman Microspectroscopy ◽  
Pig Skin ◽  
Confocal Raman Microspectroscopy ◽  
Confocal Raman

Correction for ‘Confocal Raman microspectroscopy for skin characterization: a comparative study between human skin and pig skin’ by Sana Tfaili et al., Analyst, 2012, 137, 3673–3682, DOI: 10.1039/C2AN16292J.

Depth Profiling of Poly(Methyl Methacrylate), Poly(Vinyl Alcohol) Laminates by Confocal Raman Microspectroscopy

1996 ◽  
Vol 50 (5) ◽  
pp. 558-564 ◽  
Author(s):  
Sohail Hajatdoost ◽  
Jack Yarwood
Keyword(s):  
Depth Profiling ◽  
Raman Microspectroscopy ◽  
Poly Vinyl Alcohol ◽  
Interfacial Region ◽  
Hydrogen Bonding Interaction ◽  
Molecular Weights ◽  
Bonding Interaction ◽  
Molecular Depth Profiling ◽  
Confocal Raman Microspectroscopy ◽  
Confocal Raman

We report a molecular depth profiling study of a PMMA/PVOH laminate on quartz using confocal Raman microspectroscopy. It is demonstrated that this technique can be successfully employed to study the hydrogen-bonding interaction between the ester and alcohol groups near the interfacial region. The carbonyl, v(C=O), band of PMMA shows significant broadening in the interfacial region. Various PMMA/PVOH laminates with different PMMA molecular weights have been studied, and it is demonstrated that the PMMA layers with lower molecular weight show a greater degree of interpenetration for a given annealing time.

Depth profiling of modified PVC surfaces using confocal Raman microspectroscopy

2000 ◽  
Vol 21 (13) ◽  
pp. 894-896 ◽  
Author(s):  
Javier Sacristán ◽  
Carmen Mijangos ◽  
Helmut Reinecke ◽  
Stephen Spells ◽  
Jack Yarwood
Keyword(s):  
Depth Profiling ◽  
Raman Microspectroscopy ◽  
Confocal Raman Microspectroscopy ◽  
Confocal Raman

Depth Profiling Study of Effect of Annealing Temperature on Polymer/Polymer Interfaces in Laminates Using Confocal Raman Microspectroscopy

1997 ◽  
Vol 51 (12) ◽  
pp. 1784-1790 ◽  
Author(s):  
Sohail Hajatdoost ◽  
Maurien Olsthoorn ◽  
Jack Yarwood
Keyword(s):  
Hydrogen Bonding ◽  
Annealing Temperature ◽  
Depth Profiling ◽  
Raman Microspectroscopy ◽  
Interfacial Region ◽  
Hydrogen Bonding Interaction ◽  
Bonding Interaction ◽  
Confocal Raman Microspectroscopy ◽  
Confocal Raman ◽  
Poly Acrylonitrile

The effect of annealing temperature on molecular interactions at the interface of polymer laminates is reported. Depth profiling has been carried out by using confocal Raman microspectroscopy to study poly(acrylonitrile)/poly(vinyl alcohol) (PAN/PVOH) and poly(acrylonitrile)/poly(acrylic acid) (PAN/PAA) laminates. The laminates have been annealed at 65, 75, and 90 °C. It is demonstrated that the degree of hydrogen-bonding interaction between the nitrile and alcohol groups near the interfacial region changes between laminates annealed at different temperatures. Increasing the annealing temperature up to near the glass transition temperature, Tg, of both polymers facilitates hydrogen bonding. However, above Tg, as a result of molecular flexibility, weakening of such interactions begins. Due to the lower molecular weight of PAA, and thus greater mobility in comparison with PVOH, the interfacial region of a PAN/PAA laminate is broader than that of a PAN/PVOH laminate. Hydrogen-bonding interaction between PAN and PAA was not observed. This result is rationalized by the hypothesis that, as a result of intramolecular interaction between the carbonyl and hydroxyl groups of PAA, formation of intermolecular hydrogen bonding has been hindered. In addition, the variations in the full width at half-height (FWHH) of the v(C≡N) band of a PAN–PVOH blend has been mapped by using the same technique.

Confocal Raman microspectroscopy for skin characterization: a comparative study between human skin and pig skin

The Analyst ◽  
2012 ◽  
Vol 137 (16) ◽  
pp. 3673-3682 ◽  
Author(s):  
Sana Tfaili ◽  
Cyril Gobinet ◽  
Gwendal Josse ◽  
Jean-François Angiboust ◽  
Michel Manfait ◽  
...  
Keyword(s):  
Comparative Study ◽  
Human Skin ◽  
Raman Microspectroscopy ◽  
Pig Skin ◽  
Confocal Raman Microspectroscopy ◽  
Spectral Comparison ◽  
Confocal Raman

Input of confocal Raman microspectroscopy in dermocosmetics: a spectral comparison of human skin (Transkin) and pig ear skin epidermises.

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