Anisodamine affects the pigmentation, mineral density, craniofacial area, and eye development in zebrafish embryos

2021 ◽  
Author(s):  
Binjie Wang ◽  
Tianyi Chen ◽  
Anli Wang ◽  
Jiakai Fang ◽  
Jiye Wang ◽  
...  
Keyword(s):  
Eye Development ◽  
Zebrafish Embryos ◽  
Mineral Density

Peptidomic analysis of zebrafish embryos exposed to polychlorinated biphenyls and their impact on eye development

2019 ◽  
Vol 175 ◽  
pp. 164-172 ◽  
Author(s):  
Yue Jiang ◽  
Shuchun Zhang ◽  
Xin Zhang ◽  
Nan Li ◽  
Qingyu Zhang ◽  
...  
Keyword(s):  
Polychlorinated Biphenyls ◽  
Eye Development ◽  
Zebrafish Embryos ◽  
Peptidomic Analysis

scholarly journals Early retinoic acid deprivation in developing zebrafish results in microphthalmia

2012 ◽  
Vol 29 (4-5) ◽  
pp. 219-228 ◽  
Author(s):  
HONG-GAM T. LE ◽  
JOHN E. DOWLING ◽  
D. JOSHUA CAMERON
Keyword(s):  
Retinoic Acid ◽  
Vitamin A ◽  
Eye Development ◽  
Vitamin A Deficiency ◽  
Vital Role ◽  
Zebrafish Embryos ◽  
Developmental Abnormalities ◽  
Optokinetic Reflex ◽  
Eye Size ◽  
And Behavior

AbstractVitamin A deficiency causes impaired vision and blindness in millions of children around the world. Previous studies in zebrafish have demonstrated that retinoic acid (RA), the acid form of vitamin A, plays a vital role in early eye development. The objective of this study was to describe the effects of early RA deficiency by treating zebrafish with diethylaminobenzaldehyde (DEAB), a potent inhibitor of the enzyme retinaldehyde dehydrogenase (RALDH) that converts retinal to RA. Zebrafish embryos were treated for 2 h beginning at 9 h postfertilization. Gross morphology and retinal development were examined at regular intervals for 5 days after treatment. The optokinetic reflex (OKR) test, visual background adaptation (VBA) test, and the electroretinogram (ERG) were performed to assess visual function and behavior. Early treatment of zebrafish embryos with 100 μM DEAB (9 h) resulted in reduced eye size, and this microphthalmia persisted through larval development. Retinal histology revealed that DEAB eyes had significant developmental abnormalities but had relatively normal retinal lamination by 5.5 days postfertilization. However, the fish showed neither an OKR nor a VBA response. Further, the retina did not respond to light as measured by the ERG. We conclude that early deficiency of RA during eye development causes microphthalmia as well as other visual defects, and that timing of the RA deficiency is critical to the developmental outcome.

Fine structure of the retina of the giant scallop, Placopecten magellanicus

1984 ◽  
Vol 42 ◽  
pp. 312-313
Author(s):  
C.V.L. Powell
Keyword(s):  
Fine Structure ◽  
Electron Microscope ◽  
Light Intensity ◽  
Scanning Electron Microscope ◽  
Eye Development ◽  
Preliminary Observation ◽  
Columnar Epithelium ◽  
Placopecten Magellanicus ◽  
Environmental Light ◽  
Scanning Electron

The overall fine structure of the eye in Placopecten is similar to that of other scallops. The optic tentacle consists of an outer columnar epithelium which is modified into a pigmented iris and a cornea (Fig. 1). This capsule encloses the cellular lens, retina, reflecting argentea and the pigmented tapetum. The retina is divided into two parts (Fig. 2). The distal retina functions in the detection of movement and the proximal retina monitors environmental light intensity. The purpose of the present study is to describe the ultrastructure of the retina as a preliminary observation on eye development. This is also the first known presentation of scanning electron microscope studies of the eye of the scallop.

Relationship between serum calcium levels and bone mineral density in liver transplant receipients

2001 ◽  
Vol 120 (5) ◽  
pp. A564-A564
Author(s):  
K ISLAM ◽  
S CREECH ◽  
R SOKHI ◽  
R KONDAVEETI ◽  
A NADIR ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Liver Transplant ◽  
Bone Mineral ◽  
Serum Calcium ◽  
Mineral Density

130: Role of Calcium Intake on Bone Mineral Density in Rostate Cancer Patients Under Androgen Deprivation Therapy

2006 ◽  
Vol 175 (4S) ◽  
pp. 41-42
Author(s):  
Anna Orsola ◽  
Jacques Planas ◽  
Carlos Salvador ◽  
José M. Abascal ◽  
Enrique Trilla ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Cancer Patients ◽  
Androgen Deprivation Therapy ◽  
Bone Mineral ◽  
Calcium Intake ◽  
Androgen Deprivation ◽  
Mineral Density ◽  
Rostate Cancer

Abstract #510 Mineral Metabolism and Bone Mineral Density in Patients with Neuroendocrine Tumors

2018 ◽  
Vol 24 ◽  
pp. 110-111
Author(s):  
Franco Grimaldi ◽  
Elda Kara ◽  
Fabio Vanin ◽  
Maria Carpentieri ◽  
Claudia Cipri ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Neuroendocrine Tumors ◽  
Bone Mineral ◽  
Mineral Metabolism ◽  
Mineral Density
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