The effect of maternal exposure to di-(2-ethylhexyl)-phthalate on fetal cardiac development in mice

2018 ◽  
Vol 38 (6) ◽  
pp. 834-842 ◽  
Author(s):  
Changqing Tang ◽  
Yuxin Deng ◽  
Hongyu Duan ◽  
Yi Zhang ◽  
Yifei Li ◽  
...  
Keyword(s):  
Cardiac Development ◽  
Maternal Exposure ◽  
Ethylhexyl Phthalate ◽  
Fetal Cardiac Development

scholarly journals Effects of Losartan on Angiotension Receptors During Fetal Cardiac Development in Sheep. † 137

1997 ◽  
Vol 41 ◽  
pp. 25-25
Author(s):  
Margaret Samyn ◽  
Jean Petershack ◽  
Michael S. Mathews ◽  
Jeffrey L. Segar ◽  
Jean E. Robillard
Keyword(s):  
Cardiac Development ◽  
Fetal Cardiac Development

scholarly journals Update on the Pathophysiological Implications and Clinical Role of Angiogenic Factors in Pregnancy

2015 ◽  
Vol 37 (2) ◽  
pp. 81-92 ◽  
Author(s):  
Elisa Llurba ◽  
Fatima Crispi ◽  
Stefan Verlohren
Keyword(s):  
Cardiac Development ◽  
Current Knowledge ◽  
Peripartum Cardiomyopathy ◽  
Angiogenic Factors ◽  
Clinical Role ◽  
Clinical Consequences ◽  
Vasculogenesis And Angiogenesis ◽  
Fetal Cardiac Development ◽  
In Pregnancy

Angiogenic markers are now being incorporated into clinical practice for the screening, diagnosing, and monitoring of preeclampsia. Pregnancy requires both vasculogenesis and angiogenesis in the fetal compartment and angiogenesis in the maternal compartment. Abnormal angiogenesis in the placenta determines impaired remodeling of the maternal spiral arteries and placental underperfusion that may ultimately lead to fetal growth restriction and maternal preeclampsia. The dysregulation of angiogenesis in the placenta and maternal-fetal circulation has emerged as one of the main pathophysiological features in the development of placental insufficiency and its clinical consequences. Abnormal angiogenesis has also been related to other obstetric and fetal conditions such as peripartum cardiomyopathy and fetal cardiac defects. This opens up new challenges for our understanding of angiogenic involvement in maternal cardiovascular function and fetal cardiac development, and it offers new clinical opportunities. This review summarizes the current knowledge of the pathophysiological implications and the clinical role of angiogenic factors in pregnancy.

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