scholarly journals The roles and controls of GATA factors in blood and cardiac development

IUBMB Life ◽  
2019 ◽  
Vol 72 (1) ◽  
pp. 39-44 ◽  
Author(s):  
Tomasz Dobrzycki ◽  
Mukesh Lalwani ◽  
Caroline Telfer ◽  
Rui Monteiro ◽  
Roger Patient
Keyword(s):  
Cardiac Development ◽  
Gata Factors

GATA factors in vertebrate heart development and disease

2006 ◽  
Vol 8 (22) ◽  
pp. 1-20 ◽  
Author(s):  
Alison Brewer ◽  
John Pizzey
Keyword(s):  
Transcription Factors ◽  
Heart Development ◽  
Regulatory Networks ◽  
Cardiac Development ◽  
Cellular Mechanisms ◽  
Cardiac Morphogenesis ◽  
Functional Roles ◽  
Gata Factors ◽  
Evolutionarily Conserved ◽  
Heart Formation

Vertebrate heart formation is dependent upon complex hierarchical gene regulatory networks, which effect both the specification and differentiation of cardiomyocytes and subsequently cardiac morphogenesis. GATA-4, -5 and -6 comprise an evolutionarily conserved subfamily of transcription factors, which are expressed within the precardiac mesoderm from early stages in its specification and continue to be expressed within the adult heart. We review here the functional roles of individual GATA transcription factors in cardiac development, normal homeostasis and disease. We also review the cellular mechanisms employed to regulate the expression and downstream targets of the different GATA factors.

Angiotensin2-receptors in postnatal cardiac development

2009 ◽  
Vol 56 (S 01) ◽  
Author(s):  
D Biermann ◽  
L Conradi ◽  
H Treede ◽  
A Heimann ◽  
M Didié ◽  
...  
Keyword(s):  
Cardiac Development
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