scholarly journals When proteostasis goes bad: Protein aggregation in the cell

IUBMB Life ◽  
2017 ◽  
Vol 69 (2) ◽  
pp. 49-54 ◽  
Author(s):  
Mona Radwan ◽  
Rebecca J. Wood ◽  
Xiaojing Sui ◽  
Danny M. Hatters
Keyword(s):  
Protein Aggregation ◽  
Bad Protein

An Ultra-Structural Study of Human Melanoma in Vivo and Vitro

1976 ◽  
Vol 34 ◽  
pp. 258-259
Author(s):  
James R. Gaylor ◽  
Fredda Schafer ◽  
Robert E. Nordquist
Keyword(s):  
Endoplasmic Reticulum ◽  
Golgi Apparatus ◽  
Protein Aggregation ◽  
Structural Study ◽  
Human Melanoma ◽  
Protein Matrix ◽  
Early Form ◽  
Endoplasmic Reticulum Protein ◽  
Mitochondrial Origin

Several theories on the origin of the melanosome exist. These include the Golgi origin theory, in which a tyrosinase-rich protein is "packaged" by the Golgi apparatus, thus forming the early form of the melanosome. A second theory postulates a mitochondrial origin of melanosomes. Its author contends that the melanosome is a modified mitochondria which acquires melanin during its development. A third theory states that a pre-melanosome is formed in the smooth or rough endoplasmic reticulum. Protein aggregation is suggested by one author as a possible source of the melanosome. This fourth theory postulates that the melanosome originates when the protein products of several genetic loci aggregate in the cytoplasm of the melanocyte. It is this protein matrix on which the melanin is deposited. It was with these theories in mind that this project was undertaken.

A novel P159L mutation in the Parkin gene related to autosomal dominantly inherited late onset parkinsonism and protein aggregation

2004 ◽  
Vol 31 (S 1) ◽  
Author(s):  
R Krüger ◽  
FP Marx ◽  
D Berg ◽  
C Holzmann ◽  
T Müller ◽  
...  
Keyword(s):  
Protein Aggregation ◽  
Late Onset ◽  
Parkin Gene

Plasmids Encoding Protein Aggregation Domains Act As Molecular Adjuvants for DNA Vaccines

2014 ◽  
Vol 14 (3) ◽  
pp. 161-169 ◽  
Author(s):  
Melamia Capitani ◽  
Fadi Saade ◽  
Kristina Havas ◽  
Mauro Angeletti ◽  
Fabio Concetti ◽  
...  
Keyword(s):  
Protein Aggregation ◽  
Dna Vaccines ◽  
Encoding Protein ◽  
Molecular Adjuvants

DNAJ Proteins and Protein Aggregation Diseases

2013 ◽  
Vol 999 (999) ◽  
pp. 29-35
Author(s):  
Vaishali Kakkar ◽  
Louis C. B. Prins ◽  
Harm H. Kampinga
Keyword(s):  
Protein Aggregation

DNAJ Proteins and Protein Aggregation Diseases

2013 ◽  
Vol 12 (22) ◽  
pp. 2479-2490 ◽  
Author(s):  
Vaishali Kakkar ◽  
Louis C. B. Prins ◽  
Harm H. Kampinga
Keyword(s):  
Protein Aggregation
Sign in / Sign up

Export Citation Format

Share Document