Meta‐analysis of the genetic association between maternal GNB3 C825T polymorphism and risk of pre‐eclampsia

2020 ◽  
Author(s):  
Jiajia Song ◽  
Xianping Huang ◽  
Panpan Zhou ◽  
Ting Xu ◽  
Zhangye Xu
Keyword(s):  
Genetic Association ◽  
Meta Analysis ◽  
C825t Polymorphism ◽  
Gnb3 C825t

The GNB3 C825T polymorphism and essential hypertension: a meta-analysis of 34 studies including 14 094 cases and 17 760 controls

2007 ◽  
Vol 25 (3) ◽  
pp. 487-500 ◽  
Author(s):  
Pantelis G Bagos ◽  
Antigoni L Elefsinioti ◽  
Georgios K Nikolopoulos ◽  
Stavros J Hamodrakas
Keyword(s):  
Essential Hypertension ◽  
Meta Analysis ◽  
C825t Polymorphism ◽  
Gnb3 C825t

scholarly journals The C825T Polymorphism of the G-Proteinβ3 Gene as a Risk Factor for Functional Dyspepsia: A Meta-Analysis

2016 ◽  
Vol 2016 ◽  
pp. 1-11 ◽  
Author(s):  
Yi-Zuo Song ◽  
He-Yi You ◽  
Zhe-Hui Zhu ◽  
Zheng-De Wen ◽  
Hui-Ying Xu ◽  
...  
Keyword(s):  
Risk Factor ◽  
Functional Dyspepsia ◽  
Meta Analysis ◽  
Additive Model ◽  
Gastrointestinal Disorder ◽  
Precise Estimation ◽  
C825t Polymorphism ◽  
Gnb3 C825t ◽  
The Relationship ◽  
Upper Gastrointestinal

Background. Functional dyspepsia (FD) is a functional upper gastrointestinal disorder with significant morbidity and medical costs. Previous studies investigated the association of G-proteinβ3 (GNB3) genetic polymorphisms with FD but with inconsistent results. Therefore, we performed a meta-analysis to derive a precise estimation of the relationship between GNB3 polymorphisms and FD.Methods. We searched different databases including PubMed, EMBASE, CNKI, and the Ovid Library to gather eligible studies on GNB3 polymorphisms and FD. The association was assessed by the odds ratio (OR) with 95% confidence intervals (CI).Results. We identified 12 studies with 1109 cases and 2853 controls for the analysis. We found no associations of GNB3 C825T polymorphism with FD in the overall population (T versus C, OR = 1.06, 95% CI: 0.96–1.18,P=0.26; TT versus CC + CT, OR = 1.16, 95% CI: 0.97–1.39,P=0.11; TT + CT versus CC, OR = 1.01, 95% CI: 0.77–1.31,P=0.96; TT versus CC, OR = 1.15, 95% CI: 0.93–1.44,P=0.20). Subgroup analyses by genotyping method indicated that the magnitude of association was strengthened for additive model (OR = 1.15, 95% CI: 1.07–2.24,P=0.02). Sensitivity analysis did not reveal significant associations under all models.Conclusions. This meta-analysis demonstrates that GNB3 C825T polymorphism may not be a risk factor for FD.

scholarly journals Gene-Gene and Gene-Environment Interactions in Meta-Analysis of Genetic Association Studies

PLoS ONE ◽  
2015 ◽  
Vol 10 (4) ◽  
pp. e0124967 ◽  
Author(s):  
Chin Lin ◽  
Chi-Ming Chu ◽  
John Lin ◽  
Hsin-Yi Yang ◽  
Sui-Lung Su
Keyword(s):  
Genetic Association ◽  
Association Studies ◽  
Meta Analysis ◽  
Genetic Association Studies ◽  
Gene Environment

scholarly journals Genetic association between HLA-G 14-bp polymorphism and diseases: A systematic review and meta-analysis

2018 ◽  
Vol 79 (10) ◽  
pp. 724-735 ◽  
Author(s):  
Bibiana Sgorla de Almeida ◽  
Yara Costa Netto Muniz ◽  
Alice Heidrich Prompt ◽  
Erick C. Castelli ◽  
Celso Teixeira Mendes-Junior ◽  
...  
Keyword(s):  
Systematic Review ◽  
Genetic Association ◽  
Meta Analysis ◽  
G 14

scholarly journals A systematic review and meta-analysis of genetic association studies for the role of inflammation and the immune system in diabetic nephropathy

2017 ◽  
Vol 10 (3) ◽  
pp. 293-300 ◽  
Author(s):  
Maria Tziastoudi ◽  
Ioannis Stefanidis ◽  
Georgios M. Hadjigeorgiou ◽  
Konstantinos Stravodimos ◽  
Elias Zintzaras
Keyword(s):  
Systematic Review ◽  
Diabetic Nephropathy ◽  
Immune System ◽  
Genetic Association ◽  
Association Studies ◽  
Meta Analysis ◽  
Genetic Association Studies

scholarly journals The role of G protein gene GNB3 C825T Polymorphism in HIV-1 acquisition, progression and immune activation

Retrovirology ◽  
2012 ◽  
Vol 9 (1) ◽  
pp. 1 ◽  
Author(s):  
Jennifer Juno ◽  
Jeffrey Tuff ◽  
Robert Choi ◽  
Catherine Card ◽  
Joshua Kimani ◽  
...  
Keyword(s):  
G Protein ◽  
Immune Activation ◽  
Protein Gene ◽  
C825t Polymorphism ◽  
Gnb3 C825t ◽  
Hiv 1

scholarly journals Meta-analysis of genetic association studies under heterogeneity

2012 ◽  
Vol 20 (11) ◽  
pp. 1174-1181 ◽  
Author(s):  
Binod Neupane ◽  
Mark Loeb ◽  
Sonia S Anand ◽  
Joseph Beyene
Keyword(s):  
Genetic Association ◽  
Association Studies ◽  
Meta Analysis ◽  
Genetic Association Studies
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