Enzyme‐linked immunosorbent assay ( ELISA ) versus Venereal Disease Research Laboratory test ( VDRL ) and rapid plasma reagin test ( RPR ) for screening of syphilis in pregnant women

2020 ◽  
Vol 150 (1) ◽  
pp. 103-107
Author(s):  
Dhanalakshmi Solaimalai ◽  
Swati Rathore ◽  
Manisha M. Beck ◽  
Annie Regi ◽  
Binesh L. Yesudhason ◽  
...  
Keyword(s):  
Laboratory Test ◽  
Pregnant Women ◽  
Immunosorbent Assay ◽  
Research Laboratory ◽  
Venereal Disease ◽  
Enzyme Linked Immunosorbent Assay ◽  
Venereal Disease Research Laboratory ◽  
Rapid Plasma Reagin ◽  
Disease Research

scholarly journals The Rapid Plasma Reagin Test Cannot Replace the Venereal Disease Research Laboratory Test for Neurosyphilis Diagnosis

2012 ◽  
Vol 39 (6) ◽  
pp. 453-457 ◽  
Author(s):  
Christina M. Marra ◽  
Lauren C. Tantalo ◽  
Clare L. Maxwell ◽  
Emily L. Ho ◽  
Sharon K. Sahi ◽  
...  
Keyword(s):  
Laboratory Test ◽  
Research Laboratory ◽  
Venereal Disease ◽  
Venereal Disease Research Laboratory ◽  
Rapid Plasma Reagin ◽  
Disease Research

scholarly journals Evaluation of reagin screen, a new serological test for syphilis

1976 ◽  
Vol 4 (2) ◽  
pp. 145-150
Author(s):  
J D Dyckman ◽  
R D Wende ◽  
D Gantenbein ◽  
R P Williams
Keyword(s):  
Research Laboratory ◽  
Serological Test ◽  
Venereal Disease ◽  
The Other ◽  
Screening Tests ◽  
Venereal Disease Research Laboratory ◽  
Rapid Plasma Reagin ◽  
Disease Research ◽  
Antibody Absorption

A total of 1,020 serum and plasma specimens were tested using the Venereal Disease Research Laboratory (VDRL), Rapid Plasma Reagin (RPR) card, Reagin Screen (RST) and Fluorescent Treponemal Antibody-Absorption (FTA-ABS) tests. In 257 normal patients, all screening tests were nonreactive; the FTA-ABS test was reactive for one patient. In 588 patients with treated and untreated syphilis, the RST results were 91.7% in agreement with the VDRL and RPR results. In 175 patients with diseases that cause biological false reactions, the RST was 94% in agreement with the other screening tests. The titer of the RST was within one dilution of the corresponding VDRL titer in 91.7% of the 360 speciments tested and within one dilution of the RPR titer in 96.9% of 358 specimens quantitated by both tests.

scholarly journals Frequency of reagent samples for syphilis in pregnant women treated at Distrital Leste Laboratory, Manaus, Amazonas, Brazil

2020 ◽  
Vol 10 (4) ◽  
pp. 125-130
Author(s):  
Jessica da Cruz Chagas ◽  
Aldiane Passos de Oliveira ◽  
Cleudiane Pereira de Andrade ◽  
Jander Torres da Silva ◽  
Edirany dos Santos Silva ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Research Laboratory ◽  
Venereal Disease ◽  
Test Methods ◽  
Public Health Issue ◽  
Venereal Disease Research Laboratory ◽  
Cross Sectional ◽  
Disease Research ◽  
Antibody Absorption ◽  
The City

Objective: Checking the frequency of reagent samples for syphilis in pregnant women treated at the Distrital Leste Laboratory in the city of Manaus from January 2016 to December 2018, comparing the positive VDRL (Venereal Disease Research Laboratory) cases with the confirmatory FTA-Abs (Fluorescent Treponemal Antibody Absorption Test). Methods: The study was cross-sectional and assessed the results of two syphilis diagnostic tests, VDRL and FTA-Abs. Data were obtained using the database of the electronic program SoftLab® and the Laboratory Environment Manager (GAL) and were quantitatively analyzed. Results: In 2016, 9,028 VDRL tests were performed on pregnant women, 8,562 tests in 2017 and 5,064 in 2018. From this total, 1020 tested positive for syphilis; 392 in 2016, 320 in 2017 and 308 in 2018, increasing from 4 to 6%. Comparison with the FTA-Abs was only made possible in 2016 when the diagnosis was confirmed in 82% of the tests. Conclusion: It was possible to check the frequency of pregnant women with positive and confirmatory results from 2016 to 2018, showing that although this pathology is easily preventable, it remains a challenging public health issue in pregnant women.

Sifilis Pada Kehamilan

2020 ◽  
Vol 3 (1) ◽  
pp. 73-83
Author(s):  
Hari Darmawan ◽  
Izazi Hari Purwoko ◽  
Mutia Devi
Keyword(s):  
Research Laboratory ◽  
Venereal Disease ◽  
Treponema Pallidum ◽  
Venereal Disease Research Laboratory ◽  
Rapid Plasma Reagin ◽  
Hemagglutination Assay ◽  
Disease Research

Sifilis adalah penyakit infeksi menular seksual disebabkan bakteri Treponema pallidumdapat ditularkan melalui hubungan seksual, transfusi darah, dan vertikal dari ibu ke janin.  Jika perempuan hamil menderita sifilis dapat terjadi infeksi transplasenta ke janin sehingga menyebabkan keguguran, lahir prematur, berat badan lahir rendah, lahir mati, atau sifilis kongenital. Diagnosis sifilis pada kehamilan ditegakkan berdasaranamnesis,manifestasi klinis, pemeriksaanlaboratorik, danserologik. Skrining pada trimester pertama dengan tes non-treponema seperti rapid plasma reagin(RPR) atau venereal disease research laboratory(VDRL) kombinasi dengan tes treponema seperti treponema pallidum hemagglutination assay(TPHA) merupakan hal penting pada setiap perempuan hamil. Manifestasi klinis sifilis ke janin bergantung pada usia kehamilan dan stadium sifilis maternal serta respons imun janin. Deteksi dini dan terapi adekuat penting untuk mencegah transmisi infeksi sifilis dari ibu ke janin.

Sign in / Sign up

Export Citation Format

Share Document