High-risk HPV-RNA screening of physician- and self-collected specimens for detection of cervical lesions among female sex workers in Nairobi, Kenya

2018 ◽  
Vol 143 (2) ◽  
pp. 217-224 ◽  
Author(s):  
Virginia Senkomago ◽  
Jie Ting ◽  
Jessie Kwatampora ◽  
Hannah Gukare ◽  
Nelly Mugo ◽  
...  
2012 ◽  
Vol 85 (2) ◽  
pp. 288-294 ◽  
Author(s):  
Huyen Thi Thanh Hoang ◽  
Azumi Ishizaki ◽  
Cuong Hung Nguyen ◽  
Vuong Thi Tran ◽  
Kaori Matsushita ◽  
...  

2013 ◽  
Vol 7 (1) ◽  
pp. 58-66 ◽  
Author(s):  
Melissa Soohoo ◽  
Magaly Blas ◽  
Gita Byraiah ◽  
Cesar Carcamo ◽  
Brandon Brown

Introduction:Approximately 291 million women worldwide are HPV DNA carriers. Studies have indicated that having multiple sexual partners may lead to higher HPV transmission. Thus female sex workers (FSWs) may be at greater risk of infection compared to the general population. Herein we review publications with data on FSW cervical HPV test results. We also examine variations of HPV prevalence and risk behaviors by region. Knowledge of prevalent HPV types in FSWs may lead to improved prevention measures and assist in understanding vaccination in high-risk groups.Methods:We conducted a review of the literature by searching PUBMED using the terms “prostitution” or “female sex workers”, “human papillomavirus” or “HPV”, and “prevalence” or “PCR” to find articles. We excluded studies without HPV testing or HPV type specific results, or unconventional HPV testing.Results:A total of 35 peer-reviewed publications were included in our review. High risk HPV types 16 and 18 ranged from 1.1-38.9‰ in prevalence. In addition to high-risk HPV types, newer studies reported non-carcinogenic HPV types also of high prevalence. The most prevalent HPV types reported among FSWs included HPV 6 (11.5%), 16 (38.9%), 18 (23.1%), 31 (28.4%), 52 (32.7%), and 58 (26.0%).Conclusions:Female sex workers have an overall high prevalence of HPV infection of high-risk types as evident through various testing methods. FSWs are thought to be at increased risk of cervical cancer because of high HPV exposure. This highlights the need for HPV and cervical prevention campaigns tailored to FSWs.


2005 ◽  
Vol 5 (1) ◽  
Author(s):  
Rakhi Dandona ◽  
◽  
Lalit Dandona ◽  
Juan Pablo Gutierrez ◽  
Anil G Kumar ◽  
...  

Author(s):  
Mehran Asadi-Ali Abadi ◽  
Jamileh Abolghasemi ◽  
Shahnaz Rimaz ◽  
Reza Majdzadeh ◽  
Mostafa Shokoohi ◽  
...  

2019 ◽  
Author(s):  
Afif Nurul Hidayati ◽  
A. Astindari ◽  
Maylita Sari ◽  
Dwi Murtiastutik ◽  
Sunarko Martodihardjo ◽  
...  

Female sex workers have a high risk of suffering from sexual transmitted infections (STIs). If the female sex workers suffer from STIs, besides affecting themselves, they also have potential to transmit the disease to their clients. Fluor albus is one of the symptoms of STIs. The purpose of this research is to evaluate the type of STIs that the female sex workers suffer from. This research was conducted retrospectively on 100 female sex workers in Puskesmas Putat Surabaya in 2013-2014. The result of this research showed that from 100 female sex workers, 14 subjects (14%) suffered from gonococcal cervicitis, 51 subjects (51%) suffered from nongonococcal cervicitis, 10 subjects (10%) suffered from nongonococcal cervicitis accompanied by bacterial vaginosis, 9 subjects (9%) suffered from bacterial vaginosis, 1 subject (1%) suffered from trichomoniasis, and 14 subjects (14%) had no data. This research concluded that nongonococcal cervicitis is the most major cause of STIs suffered by female sex workers. Therefore, the vigilances to prevent transmission of nongonococcal infection to the clients is highly needed.


2020 ◽  
Vol 31 (2) ◽  
pp. 109-118
Author(s):  
Kristen Sweet ◽  
Claire Bosire ◽  
Busola Sanusi ◽  
Carly J Sherrod ◽  
Jessie Kwatampora ◽  
...  

Female sex workers (FSWs) have a notably high risk of acquiring human papillomavirus (HPV) infections. Relatively few studies address the type-specific prevalence and incidence of HPV among FSWs in sub-Saharan Africa. FSWs (n = 348) attending the Korogocho clinic in Nairobi, Kenya participated from August 2009 to March 2011. HPV DNA was detected using the SPF10-LiPA25 PCR assay. Baseline prevalence of HPV infection and cervical dysplasia were calculated, stratified by HIV-serostatus. Incidence rate (IR) of infection was calculated as number of new infections from baseline over person-months among 160 HPV-negative participants with complete 12-month follow-up. Baseline HPV prevalence was 23.6% for any HPV and 20.4% for high-risk HPV (hrHPV) types. Most prevalent types were HPV52 (10.1%), HPV35 (2.3%), and HPV51 (2.3%). A quarter (24%) of participants were HIV-positive. HPV prevalence was higher in HIV-positive (32.1%) than HIV-negative (20.8%) participants. hrHPV prevalence was higher in HIV-positive (27.4%) than HIV-negative (18.2%) women. During follow-up, HPV IR was 31.4 (95% CI: 23.8–41.5) for any HPV and 24.2 (95% CI: 17.9–32.8) for hrHPV types. HPV52 had the highest IR (6.0; 95% CI: 6.5–10.3). Overall HPV and hrHPV prevalence were lower than expected, but both prevalence and incidence were higher in HIV-positive than in HIV-negative women.


2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Abdul Rashid Adams ◽  
Priscillia Awo Nortey ◽  
Benjamin Ansah Dortey ◽  
Richard Harry Asmah ◽  
Edwin Kwame Wiredu

Cervical cancer is a largely preventable disease mediated by persistent infection with high-risk Human Papillomaviruses (Hr-HPV). There are now three approved vaccines against the most common HPV genotypes. In Ghana, mortality due to cervical cancer is on the rise, due to the absence of an organized and effective cervical cancer prevention and control program. Data on circulating HPV genotypes is important for studying the likely impact of mass introduction of HPV vaccination of the female population before sexual debut. High HPV prevalence has been reported in Female Sex Workers (FSWs), who constitute an important active group for maintenance of HPV in the population. This study was conducted to determine the size of HPV prevalence in this group and to provide information for future assessment of the impact of vaccine introduction in the country. We conducted a cross-sectional study where the snowballing technique was used to identify and select FSW’s ≥18 years, operating within suburbs of Greater Accra Region (GAR). A risk factor assessment interview was conducted and cervical swabs were collected for HPV-DNA detection and genotyping by Nested Multiplex PCR. Hundred participants, age ranging from 18 to 45 years, median 24 years, were studied. The prevalence of Cervical HPV was 26%. Eleven genotypes were detected comprising 9 high-risk in order of decreasing prevalence HPV-16 (8%), HPV-35 (5%), HPV-33/39/-68 (3%), HPV-52/51/59 (2%) and HPV-18 (1%) and 2 Low-risk types, HPV-42(3%), and HPV-43 (1%). Three women had HPV types that could not be genotyped by our method. Oral contraceptives use was associated with a reduced chance of HPV infection (P=0.002; OR=0.19, 95% CI 0.07-0.54). This study found a high HPV prevalence among FSWs in the GAR. A high number of Hr-HPV genotypes seen are vaccine preventable, providing additional compelling argument for implementing a national cervical cancer prevention plan including vaccination.


AIDS ◽  
2000 ◽  
Vol 14 (16) ◽  
pp. 2523-2534 ◽  
Author(s):  
Catherine M. Lowndes ◽  
Michel Alary ◽  
Cyriaque A. B. Gnintoungbé ◽  
Emmanuelle Bédard ◽  
Léonard Mukenge ◽  
...  

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