Effect of BMI on pregnancy rates following ovulation induction and assisted conception among women in Qatar experiencing infertility

2018 ◽  
Vol 141 (3) ◽  
pp. 389-390
Author(s):  
Sufia Athar ◽  
Mohammad A. Hamcho ◽  
Amna K. Tellisi ◽  
Rohini Puttegowda ◽  
Vincent Boama
2021 ◽  
pp. 501-542
Author(s):  
Alice Denga

This chapter covers issues related to fertility and subfertility. It starts with lifestyle assessments that should be done as part of preconceptual care, and explains the psychological effects and counselling for subfertility alongside both male and female factors that affect difficulties in conceiving. Tests and investigations are covered for both partners, and the role of the fertility nurse specialist is defined. Ovulation induction, assisted conception, inter-uterine insemination, and IVF are all described. Pre-implantation genetic diagnosis is given a brief overview, and the chapter also explores adoption and surrogacy. Fertility preservation and the role of the Human Fertilization and Embryology Authority are covered.


2004 ◽  
Vol 82 ◽  
pp. S143
Author(s):  
C. Morelli ◽  
N. Virji ◽  
J. Stelling ◽  
K. Cain ◽  
G. San Roman

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Ariadne Daniel ◽  
Shereen Ezzat ◽  
Ellen Greenblatt

Objective. To report the prestimulation use of adjuvant GH for gonadotropin ovulation induction in a woman with hypopituitarism and GH deficiency who previously failed to respond.Design, Patients, and Measurements. A 31-year-old nulliparous woman presented with hypopituitarism and GH deficiency after failing ovulation induction with high dose gonadotropins. A trial of GH was undertaken for 5 months prior to ovulation induction resulting in normalization of IGF-I levels.Results. Women with hypopituitarism are known to have lower pregnancy rates after ovulation induction with need for higher doses of gonadotropins. A small subset of these patients do not ovulate. This patient had successful ovulation induction and pregnancy with prestimulation GH.Conclusions. This case suggests that the use of adjuvant GH in a GH-deficient patient several months before the use of human menopausal gonadotropin results in ovulation and pregnancy.


2020 ◽  
Author(s):  
Zhong-Kai Wang ◽  
She-ling Wu ◽  
Xiao-Na Yu ◽  
Hong-Wu Qiao ◽  
Hua Lou ◽  
...  

Abstract Objective: To evaluate the effectiveness of highly purified human menopausal gonadotropins (hp-HMG) plus recombinant follicle stimulating hormone (r-FSH) vs r-FSH vs r-FSH plus recombinant luteinizing hormone (r-LH) in vitro fertilization (IVF) / intracytoplasmic sperm injection (ICSI) patients。Design :Retrospective cohort studyMethods:This was a retrospective study. Among a total number of 3568 patients who had undergone IVF/ICSI applications, 409 eligible patients were included.Total units of follitropin alpha preparations used in ovulation induction, total number of meiois-2 phase oocytes, total number of used oocytes in ICSI cycle, fertilization rate and clinical pregnancy rates of both groups were analyzed. In this retrospective cohort study, women undergoing IVF/ICSI Gonadotropin releasing hormone (GnRH) antagonist cycles downregulation. 409 patients were included in the study. Among them One group followed the current standard protocol of no LH or hp-HMG supplementation given(n=64). The other had LH supplementation in the form of r -LH (Luveris; Merck Serono, Switzerland) (n=221), Another group had hp-HMG supplementation in the form of hp-HMG (Menopur , Ferring,Germany)(n=121).In the Subgroup analysis were decided by AFC ,7 < AFC〈20 or AFC>20 of the three group.Result: Mean duration of stimulation and was longer in the group of patients treated with hp-HMG plus rFSH compared to the group of patients treated with r-FSH and the group of r-LH plus r-FSH (13.24 days and 12.72days and12.21days, respectively; P<0.05). The amount of GN does for patients treated withhp-HMG plus rFSH compared to the group of patients treated with r-FSH plus r-LH and the group of r-FSH alone respectively (P<0.05). Clinical pregnancy rates were 76.6% and 60.9% and 62.9% (P<0.05)in the groups of patients treated with hp-hMG plus rFSH, r-FSH plus r-LH,r-FSHalonerespectively. What’s morea greater live birth rate was noted in the hp-hMG plus r-FSH group, there was statistically significant difference between the three groups (P>0.05).in the subgroup analysis when AFC>20 hp-HMG plus rFSH group have more lower ovarian hyperstimulation syndrome (OHSS) than r-FSH plus r-LH and rFSH alone,respectively.Clonclusion:The higher oocyte yield with r-FSH does not result in higher quality embryos.hp-HMG or r-LH supplementation is an option for improving IVF outcome in patients ovulation induction with r-FSH during GnRH agonist down-regulation. Particularly, hp-HMG is recommended as it may have a beneficial action on implantation in selected group especially AFC more than 20patients.


Sign in / Sign up

Export Citation Format

Share Document