scholarly journals A decision analytic model for prevention of hepatitis B virus infection in Sub-Saharan Africa using birth-dose vaccination

2018 ◽  
Vol 141 (1) ◽  
pp. 126-132 ◽  
Author(s):  
Sarah Anderson ◽  
Lorie M. Harper ◽  
Jodie Dionne-Odom ◽  
Gregory Halle-Ekane ◽  
Alan T.N. Tita
Keyword(s):  
Hepatitis B Virus ◽  
Virus Infection ◽  
Hepatitis B ◽  
Sub Saharan Africa ◽  
Decision Analytic Model ◽  
Hepatitis B Virus Infection ◽  
Analytic Model ◽  
B Virus ◽  
Birth Dose ◽  
Sub Saharan

scholarly journals Clinical Characteristics of Chronic Hepatitis B Virus Infection in Immigrants From Sub-Saharan Africa

2011 ◽  
Vol 140 (5) ◽  
pp. S-970-S-971
Author(s):  
Kathleen Buchheit ◽  
Prameela Rao ◽  
Ju-En C. Thlick ◽  
John F. Reinus ◽  
Hatef Massoumi
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis B Virus ◽  
Virus Infection ◽  
Hepatitis B ◽  
Clinical Characteristics ◽  
Sub Saharan Africa ◽  
Hepatitis B Virus Infection ◽  
Chronic Hepatitis B Virus ◽  
B Virus ◽  
Sub Saharan

Global dynamics of a model of hepatitis B virus infection in a sub-Saharan African rural area

2020 ◽  
Vol 13 (06) ◽  
pp. 2050054
Author(s):  
Jean Pierre II Kouenkam ◽  
Joseph Mbang ◽  
Yves Emvudu
Keyword(s):  
Hepatitis B Virus ◽  
Virus Infection ◽  
Hepatitis B ◽  
Numerical Simulations ◽  
Rural Area ◽  
Mass Vaccination ◽  
Endemic Equilibrium ◽  
Hepatitis B Virus Infection ◽  
B Virus ◽  
Sub Saharan

We formulate and systematically study a deterministic compartmental model of Hepatitis B. This model has some important and novel features compared with the well-known basic model in the literature. Specifically, it takes into account the differential susceptibility that follows the vaccine formulation employing three-doses schedule. It points up the HbeAg status of carriers, their levels of viral replication, the fact that treatment being not curative is recommended only to a small proportion of chronic carriers, and finally the fact that only inactive carriers are able to recover from disease. The model has simple dynamical behavior which has a globally asymptotically stable disease-free equilibrium when the basic reproduction number [Formula: see text] and an endemic equilibrium when [Formula: see text]. By the use of Lyapunov functions, when it exists, we prove the global asymptotic stability of the endemic equilibrium under some conditions. Using data from Tokombere, a rural area in Cameroon, numerical simulations are performed. These numerical simulations first confirm analytical results, second they suggest that a policy based on treatment could not significantly impact the course of the infection. Third, they show as it is well known that vaccination is a very effective measure to control the infection. Furthermore, they show that neonatal vaccination influences more the course of infection than mass vaccination strategy. Nevertheless, they picture how much loss between consecutive doses of vaccine could be harmful. Finally, it is suggested that for a Sub-saharan African rural area, two-thirds of expected incidence of Hepatitis B virus infection and one third of expected prevalence of chronic carriers could be averted by 2030 if the birth dose vaccination becomes systematic and if mass vaccination rate increases to up 10%.

scholarly journals 390: Prevention of hepatitis B in sub-Saharan Africa: a decision analytic model for the birth dose vaccine

2017 ◽  
Vol 216 (1) ◽  
pp. S234
Author(s):  
Sarah Anderson ◽  
Lorie Harper ◽  
Jodie Dionne-Odom ◽  
Gregory H. Ekane ◽  
Alan Tita
Keyword(s):  
Hepatitis B ◽  
Sub Saharan Africa ◽  
Decision Analytic Model ◽  
Analytic Model ◽  
Birth Dose ◽  
Sub Saharan ◽  
Dose Vaccine

scholarly journals Modelling hepatitis B virus infection and impact of timely birth dose vaccine: A comparison of two simulation models

PLoS ONE ◽  
2020 ◽  
Vol 15 (8) ◽  
pp. e0237525
Author(s):  
Margaret J. de Villiers ◽  
Ivane Gamkrelidze ◽  
Timothy B. Hallett ◽  
Shevanthi Nayagam ◽  
Homie Razavi ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Virus Infection ◽  
Hepatitis B ◽  
Simulation Models ◽  
Hepatitis B Virus Infection ◽  
B Virus ◽  
Birth Dose ◽  
Dose Vaccine
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