scholarly journals Association of genomic variants at the human leukocyte antigen locus with cervical cancer risk, HPV status and gene expression levels

2020 ◽  
Vol 147 (9) ◽  
pp. 2458-2468 ◽  
Author(s):  
Dhanya Ramachandran ◽  
Peter Schürmann ◽  
Qianqian Mao ◽  
Yingying Wang ◽  
Lisa‐Marie Bretschneider ◽  
...  
2002 ◽  
Vol 186 (11) ◽  
pp. 1565-1574 ◽  
Author(s):  
Margaret M. Madeleine ◽  
Babette Brumback ◽  
Kara L. Cushing‐Haugen ◽  
Stephen M. Schwartz ◽  
Janet R. Daling ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-13 ◽  
Author(s):  
Lin Cheng ◽  
Yan Guo ◽  
Shipeng Zhan ◽  
Peiyuan Xia

Objective. We aimed to derive a more precise estimation of the associations between human leukocyte antigens DP (HLA-DP) gene polymorphisms and cervical cancer risk by meta-analysis. Methods. PubMed, EMBASE, ScienceDirect, Web of Science, Chinese National Knowledge Infrastructure (CNKI), and Wanfang databases were systematically searched to identify studies investigating the relationship between HLA-DP gene polymorphisms and cervical cancer. The associations between them were evaluated by pooled OR and 95% CI. Results. A total of 11 studies including 5008 cases and 9322 controls with 11 HLA-DP alleles were included in the current meta-analysis. Results. The results showed that HLA-DPB1⁎03:01 was significantly associated with an increased risk of cervical cancer (OR=1.252, 95%CI: 1.116-1.403, Pz=0.001), while HLA-DPB1⁎04:02 and HLA-DP rs3117027 G allele were significantly associated with a decreased risk of cervical cancer (OR=0.744, 95%CI: 0.652-0.848, Pz=0.001; OR=0.790, 95%CI: 0.745-0.837, Pz=0.001), and HLA-DP rs9277535 G allele was significantly associated with a decreased risk of cervical cancer in Asia (OR=0.802, 95%CI: 0.753-0.855, Pz=0.001). Subgroup analyses based on race system showed that HLA-DPB1⁎13:01 was significantly associated with an increased risk of cervical cancer in Asia (OR=1.834, 95%CI: 1.107-3.039, Pz=0.019). No significant association was established for the HLA-DP following alleles: DPB1⁎02:01, DPB1⁎02:02, DPB1⁎04:01, DPB1⁎05:01, rs4282438, and rs3077. Conclusion. HLA-DP gene polymorphisms (HLA-DPB1⁎03:01, DPB1⁎04:02, DPB1⁎13:01, rs9277535, and rs3117027) were significantly associated with cervical cancer.


Author(s):  
Dhanya Ramachandran ◽  
Yingying Wang ◽  
Peter Schürmann ◽  
Fabienne Hülse ◽  
Qianqian Mao ◽  
...  

Heliyon ◽  
2021 ◽  
Vol 7 (1) ◽  
pp. e05919
Author(s):  
Shiba Das ◽  
Lutfur Naher ◽  
Tutun Das Aka ◽  
Md. Abdul Aziz ◽  
Samia Shabnaz ◽  
...  

2010 ◽  
Vol 197 (2) ◽  
pp. 174-178 ◽  
Author(s):  
Pei Jiang ◽  
Jianxin Liu ◽  
Xiaoxi Zeng ◽  
Wen Li ◽  
Jianxin Tang

1987 ◽  
Vol 42 (1) ◽  
pp. 64-65
Author(s):  
M. V. ZUNZUNEGUI ◽  
M.-C. KING ◽  
C. F. CORIA ◽  
J. CHARLET

2017 ◽  
Vol 141 (3) ◽  
pp. 488-496 ◽  
Author(s):  
Eliane Rohner ◽  
Mazvita Sengayi ◽  
Bridgette Goeieman ◽  
Pamela Michelow ◽  
Cynthia Firnhaber ◽  
...  

2017 ◽  
Vol 26 (3) ◽  
pp. 437.2-437
Author(s):  
BM Bernardo ◽  
PL Reiter ◽  
ML Pennell ◽  
TJ Padamsee ◽  
MT Ruffin ◽  
...  

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