scholarly journals Thyroid cancer incidence near nuclear sites in Belgium: An ecological study at small geographical level

2020 ◽  
Vol 146 (11) ◽  
pp. 3034-3043
Author(s):  
Claire Demoury ◽  
Harlinde De Schutter ◽  
Christel Faes ◽  
Sylviane Carbonnelle ◽  
Sébastien Fierens ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Incidence ◽  
Ecological Study ◽  
Thyroid Cancer Incidence

scholarly journals Ecological Study on Thyroid Cancer Incidence and Mortality in Association with European Union Member States’ Air Pollution

2020 ◽  
Vol 18 (1) ◽  
pp. 153
Author(s):  
Evanthia Giannoula ◽  
Christos Melidis ◽  
Savvas Frangos ◽  
Nikitas Papadopoulos ◽  
Georgia Koutsouki ◽  
...  
Keyword(s):  
Air Pollution ◽  
Thyroid Cancer ◽  
Cancer Incidence ◽  
Ecological Study ◽  
Positive Association ◽  
Significant Positive Association ◽  
Member States ◽  
Eu Member States ◽  
Incidence And Mortality ◽  
Thyroid Cancer Incidence

Over the last few decades, thyroid cancer incidence has had a significant increase. Despite well-known genetic and epigenetic factors (radiation, overdiagnosis, already existing benign thyroid tumors), the effect of air pollution on its incidence and mortality has not yet been fully elucidated. In this study, air pollution data from 27 EU member states is used in order to analyze its association with thyroid cancer incidence, and mortality and socioeconomic factors are examined as confounders. This ecological study used age standardized thyroid cancer incidence and mortality rates per 100,000 people for the year 2012 from 27 EU member states, collected from the International Agency for Research on Cancer, World Health Organization and European Cancer. Data regarding mean air pollutant mass concentrations for 1992, 2002 and 2012 was collected from the European Environment Agency. Data analysis was carried out using Prism 5.0 and SPSS v.20. Multiple regression analysis showed a statistically significant positive association between thyroid cancer incidence in men and the environmental 2012 masse of Benzo (k) Fluoranthene (r2 = 0.2142, p = 0.042) and HexaChlorocycloHexane (r2 = 0.9993, p = 0.0166). Additionally, a statistically significant positive association was observed between the thyroid cancer mortality rate in men and the 1992 environmental concentrations of Hg (r2 = 0.1704, p = 0.043). Data indicates that some air pollutants may have an effect on increased thyroid cancer incidence and mortality, at least in men. However, causal relationships cannot be fully supported via ecological studies, and this article only focuses on the EU and uses only three distinct time periods.

scholarly journals Association between Uranium Exposure and Thyroid Health: A National Health and Nutrition Examination Survey Analysis and Ecological Study

2020 ◽  
Vol 17 (3) ◽  
pp. 712 ◽  
Author(s):  
Maaike van Gerwen ◽  
Naomi Alpert ◽  
Wil Lieberman-Cribbin ◽  
Peter Cooke ◽  
Kimia Ziadkhanpour ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
National Health ◽  
Cancer Incidence ◽  
Ecological Study ◽  
Incidence Rates ◽  
Thyroid Peroxidase ◽  
Nutrition Examination Survey ◽  
Health And Nutrition ◽  
Thyroid Cancer Incidence ◽  
Cancer Incidence Rates

Besides specific, incidental radiation exposure, which has been associated with increased thyroid cancer risk, the effects of exposure to background radiation from uranium, a naturally occurring, radioactive, and ubiquitous element, on the thyroid gland has not been widely studied. We therefore investigated the association between uranium exposure and thyroid health in the US. Using the National Health and Nutrition Examination Survey (NHANES), we assessed the association between urinary uranium levels and thyroid-related antibodies, including thyroglobulin antibodies (TgAb) and anti-thyroid peroxidase (anti-TPO), in the general population. Secondly, we performed an ecological study of age-adjusted thyroid cancer incidence rates per state and sources of uranium exposure. We included 3125 eligible participants from the NHANES and found a significant association between increased TgAb and increased urinary uranium levels when analyzed as quartiles (p = 0.0105), while no association was found with anti-TPO. In addition, although no significant correlation was found in the ecological study, certain states had high age-adjusted thyroid cancer incidence rates and a high number of uranium activity locations and high uranium concentrations in water. The present study suggests that uranium exposure may affect thyroid health, which warrants increased sampling of soil and water in high-risk states.

scholarly journals Ambient air pollution exposure and thyroid cancer incidence in Iran

2021 ◽  
Author(s):  
Samaneh Dehghani ◽  
Arefe Abedinzade ◽  
Mohebat Vali
Keyword(s):  
Air Pollution ◽  
Thyroid Cancer ◽  
Cancer Incidence ◽  
Ambient Air ◽  
Ambient Air Pollution ◽  
Ozone Pollution ◽  
Annual Percent Change ◽  
Female Population ◽  
Percent Change ◽  
Thyroid Cancer Incidence

Introduction: Thyroid cancer is the most common endocrine malignant that is three times more prevalent in women than men. Fine particulate matter (PM2.5) has been indicated to affect Thyroid Hormone (TH) homeostasis. We sought to estimate the association between long-term exposure to ambient air pollution and the incidence of thyroid cancer in the Iranian female population. Materials and methods: We extracted thyroid cancer incidence and ambient air pollution data from Iran from 2000 to 2019 for males and females for all age groups from the Global Burden of Disease (GBD) dataset. We entered the data into Joinpoint to present Annual Percent Change (APC) and Average Annual Percent Change (AAPC) and its confidence intervals. We entered the information into R3.5.0. Results: Thyroid cancer in females had an upward trend [AAPC=4.9% (4.2-5.6)]. There was a correlation between ambient PM pollution (p≤0.001, r=0.84) and ambient ozone pollution (p≤0.001, r=0.94), and the incidence of thyroid cancer in females. The results of the analysis also showed a significant relationship between thyroid cancer incidence in females and secondhand  smoke (p≤0.001, r=0.74). Conclusion: This study indicated increasing trends in thyroid cancer incidence with exposure to ambient air pollution. Our novel findings provide additional insight into the potential associations between risk factors and thyroid cancer and warrant further investigation, specifically in areas with high levels of air pollution both nationally and internationally. However, causal relationships cannot be fully supported via ecological studies, and this article only focuses on Iran.

SP193 – Changes in thyroid cancer incidence in Scotland post-Chernobyl

2009 ◽  
Vol 141 (3) ◽  
pp. P146-P147
Author(s):  
Jason Fleming ◽  
Karan Kapoor ◽  
Ian Myles Black
Keyword(s):  
Thyroid Cancer ◽  
Cancer Incidence ◽  
Thyroid Cancer Incidence
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