scholarly journals Breast cancer incidence and mortality before and after implementation of the German mammography screening program

2019 ◽  
Vol 147 (3) ◽  
pp. 709-718 ◽  
Author(s):  
Alexander Katalinic ◽  
Nora Eisemann ◽  
Klaus Kraywinkel ◽  
Maria R. Noftz ◽  
Joachim Hübner
Keyword(s):  
Breast Cancer ◽  
Cancer Incidence ◽  
Mammography Screening ◽  
Screening Program ◽  
Breast Cancer Incidence ◽  
Incidence And Mortality ◽  
Before And After ◽  
Mammography Screening Program

scholarly journals Radiation-Induced Breast Cancer Incidence and Mortality From Digital Mammography Screening

2016 ◽  
Vol 164 (4) ◽  
pp. 205 ◽  
Author(s):  
Diana L. Miglioretti ◽  
Jane Lange ◽  
Jeroen J. van den Broek ◽  
Christoph I. Lee ◽  
Nicolien T. van Ravesteyn ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Incidence ◽  
Digital Mammography ◽  
Mammography Screening ◽  
Breast Cancer Incidence ◽  
Incidence And Mortality ◽  
Radiation Induced

Breast cancer incidence and mortality in the Nordic capitals, 1970–1998. Trends related to mammography screening programmes

2006 ◽  
Vol 45 (5) ◽  
pp. 528-535 ◽  
Author(s):  
Sven Törnberg ◽  
Levent Kemetli ◽  
Elsebeth Lynge ◽  
Anne Helene Olsen ◽  
Solveig Hofvind ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Incidence ◽  
Mammography Screening ◽  
Breast Cancer Incidence ◽  
Incidence And Mortality

scholarly journals Trends in Breast Cancer Incidence and Stage Distribution Before and During the Introduction of the Mammography Screening Program in Lithuania

2019 ◽  
Vol 26 (1) ◽  
pp. 107327481882109 ◽  
Author(s):  
Laura Steponaviciene ◽  
Ruta Briediene ◽  
Rasa Vanseviciute ◽  
Giedre Smailyte
Keyword(s):  
Breast Cancer ◽  
Mammography Screening ◽  
Screening Program ◽  
Breast Cancer Incidence ◽  
Age Groups ◽  
Target Population ◽  
Steady Increase ◽  
Incidence Trends ◽  
Implementation Period ◽  
Mammography Screening Program

Background: The aim of this study was to analyze the incidence trends of localized and advanced breast cancer (BC) before and during the implementation of the mammography screening program (MSP) in Lithuania. Methods: The study period was divided into 2 intervals: the prescreening period (1998-2005) and implementation period (2006-2012). Analysis was performed for 3 age-groups: 0 to 49 years, 50 to 69 (target population), and older than 70. Results: In all age-groups, the incidence of localized BC has shown a steady increase, while the incidence of advanced stage BC has decreased. In the target population, during the study period, the stage I BC incidence increased statistically significantly by 10.3% per year (from 3.3 per 100 000 in 1998 to 12.2 per 100 000 in 2012). The increase in localized BC was faster in the period before the implementation of the MSP than during the implementation in 2006 to 2012 (10.3% and 5.7%). A slightly statistically significant decrease was observed for advanced BC during the study period (−1.1% per year), while during the implementation of the MSP, significant changes were not seen. Conclusions: The results of our study indicate that the implementation of the MSP in Lithuania did not significantly influence trends of localized and advanced BC. Changes observed during the study period, including the prescreening and screening introduction periods, may reflect the general trends in the awareness of BC and improvements in diagnostics.

scholarly journals Breast cancer incidence and mortality in Tyrol/Austria after fifteen years of opportunistic mammography screening

2010 ◽  
Vol 10 (1) ◽  
Author(s):  
Willi Oberaigner ◽  
Wolfgang Buchberger ◽  
Thomas Frede ◽  
Rudolf Knapp ◽  
Christian Marth ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Incidence ◽  
Mammography Screening ◽  
Breast Cancer Incidence ◽  
Incidence And Mortality

scholarly journals Is mammography screening beneficial: An individual-based stochastic model for breast cancer incidence and mortality

2020 ◽  
Author(s):  
Thuy T. T. Le ◽  
Frederick R. Adler
Keyword(s):  
Breast Cancer ◽  
Cancer Progression ◽  
Cancer Incidence ◽  
Mammography Screening ◽  
Mechanistic Model ◽  
Breast Cancer Incidence ◽  
Published Data ◽  
National Breast ◽  
Incidence And Mortality ◽  
Screening Study

AbstractBACKGROUNDThe benefits of mammography screening have been controversial, with conflicting findings from various studies.METHODSWe hypothesize that unmeasured heterogeneity in tumor aggressiveness underlies these conflicting results. Based on published data from the Canadian National Breast Screening Study (CNBSS), we develop and parameterize an individual-based mechanistic model for breast cancer incidence and mortality that tracks five stages of breast cancer progression and incorporates the effects of age on breast cancer incidence and all-cause mortality.RESULTSThe model accurately reproduces the reported outcomes of the CNBSS. By varying parameters, we predict that the benefits of mammography depend on the effectiveness of cancer treatment and tumor.CONCLUSIONSIn particular, patients with the most rapidly growing or potentially largest tumors have the highest benefit and least harm from the screening, with only a relatively small effect of age. However, the model predicts that confining mammography populations with a high risk of acquiring breast cancer increases the screening benefit only slightly compared with the full population.

scholarly journals Comparing CISNET Breast Cancer Incidence and Mortality Predictions to Observed Clinical Trial Results of Mammography Screening from Ages 40 to 49

2018 ◽  
Vol 38 (1_suppl) ◽  
pp. 140S-150S ◽  
Author(s):  
Jeroen J. van den Broek ◽  
Nicolien T. van Ravesteyn ◽  
Jeanne S. Mandelblatt ◽  
Hui Huang ◽  
Mehmet Ali Ergun ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Incidence ◽  
Cancer Mortality ◽  
Mammography Screening ◽  
Breast Cancer Mortality ◽  
Breast Cancer Incidence ◽  
Mortality Reduction ◽  
Incidence And Mortality ◽  
The Uk

Background. The UK Age trial compared annual mammography screening of women ages 40 to 49 years with no screening and found a statistically significant breast cancer mortality reduction at the 10-year follow-up but not at the 17-year follow-up. The objective of this study was to compare the observed Age trial results with the Cancer Intervention and Surveillance Modeling Network (CISNET) breast cancer model predicted results. Methods. Five established CISNET breast cancer models used data on population demographics, screening attendance, and mammography performance from the Age trial together with extant natural history parameters to project breast cancer incidence and mortality in the control and intervention arm of the trial. Results. The models closely reproduced the effect of annual screening from ages 40 to 49 years on breast cancer incidence. Restricted to breast cancer deaths originating from cancers diagnosed during the intervention phase, the models estimated an average 15% (range across models, 13% to 17%) breast cancer mortality reduction at the 10-year follow-up compared with 25% (95% CI, 3% to 42%) observed in the trial. At the 17-year follow-up, the models predicted 13% (range, 10% to 17%) reduction in breast cancer mortality compared with the non-significant 12% (95% CI, -4% to 26%) in the trial. Conclusions. The models underestimated the effect of screening on breast cancer mortality at the 10-year follow-up. Overall, the models captured the observed long-term effect of screening from age 40 to 49 years on breast cancer incidence and mortality in the UK Age trial, suggesting that the model structures, input parameters, and assumptions about breast cancer natural history are reasonable for estimating the impact of screening on mortality in this age group.

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