scholarly journals Trends in the risk and burden of second primary malignancy among survivors of smoking‐related cancers in the United States

2019 ◽  
Vol 145 (1) ◽  
pp. 143-153 ◽  
Author(s):  
Eric Adjei Boakye ◽  
Paula Buchanan ◽  
Leslie Hinyard ◽  
Nosayaba Osazuwa‐Peters ◽  
Matthew C. Simpson ◽  
...  
Keyword(s):  
United States ◽  
The United States ◽  
Second Primary ◽  
Second Primary Malignancy ◽  
Primary Malignancy

scholarly journals Incidence of adrenal gland tumor as a second primary malignancy: SEER-based study

2018 ◽  
Vol 7 (10) ◽  
pp. 1040-1048 ◽  
Author(s):  
Wafaa M Rashed ◽  
Anas Saad ◽  
Muneer Al-Husseini ◽  
Ahmed Mahmoud Galal ◽  
Assem Mohamed Ismael ◽  
...  
Keyword(s):  
Adrenal Gland ◽  
Cancer Treatment ◽  
The United States ◽  
Adrenal Tumors ◽  
Second Primary ◽  
Gland Tumor ◽  
Second Primary Malignancy ◽  
Primary Malignancy ◽  
Primary Tumors ◽  
Cancer Networks

Purpose Advances in cancer treatment achieved during the past decades have resulted in increased survival of most pediatric and adult patients that suffered from different adrenal tumor types. This article reviews the incidence and survival of adrenal gland tumors as second primary tumors, according to data from the Surveillance, Epidemiology, and End Results (SEER) database. Methods The SEER 13 Registries Database from 1992 to 2013 was used. All primary cancer sites were selected using the multiple primary standardized incidence ratios (MP-SIR) session. Results Data for a total of 2,887,468 persons with cancer were reviewed; 117 of whom had suffered second primary adrenal tumors. The overall SIR of adrenal gland tumor as a second primary was 1.5. A high incidence ratio of the event was detected in specific primary tumor sites: hypopharynx (observed/expected (O/E) = 44.6); other endocrine tissue (including the thymus) (O/E = 38.3); small intestine (O/E = 8.9); liver (O/E = 8.7); stomach (O/E = 5); nodal NHL (O/E = 3.8); kidney and renal pelvis (O/E = 3.2) and breast (O/E = 1.8). Conclusion The underlying shared mechanisms should be investigated between adrenal tumors and hypopharyngeal, endocrine and other tumors. Racial disparity is an important challenge in cancer treatment at the United States and should be taken into consideration in the design of cancer prevention programs. This could be achieved through follow-up programs at specialized national cancer networks, especially for rare tumors like adrenal gland.

Occurrence of second primary malignancy in medullary thyroid cancer (MTC) patients

2019 ◽  
Author(s):  
George Simeakis ◽  
Katerina Saltiki ◽  
Evangelia Zapanti ◽  
Evanthia Kassis ◽  
Maria Alevizaki
Keyword(s):  
Thyroid Cancer ◽  
Medullary Thyroid Cancer ◽  
Second Primary ◽  
Second Primary Malignancy ◽  
Primary Malignancy ◽  
Medullary Thyroid

Second primary malignancy of the aerodigestive tract in patients treated for cancer of the oral cavity and larynx

Head & Neck ◽  
2005 ◽  
Vol 27 (12) ◽  
pp. 1042-1048 ◽  
Author(s):  
Karen Lin ◽  
Snehal G. Patel ◽  
Pen Yuan Chu ◽  
Jeannette M. S. Matsuo ◽  
Bhuvanesh Singh ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Aerodigestive Tract ◽  
Second Primary ◽  
Second Primary Malignancy ◽  
Primary Malignancy

The risk and prognosis of secondary primary malignancy in lung cancer: a population-based study

2021 ◽  
Author(s):  
Jia Hong ◽  
Rongrong Wei ◽  
Chuang Nie ◽  
Anastasiia Leonteva ◽  
Xu Han ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Overall Survival ◽  
Cox Regression ◽  
Population Based ◽  
Second Primary ◽  
Second Primary Malignancy ◽  
Risk Models ◽  
Primary Malignancy ◽  
Population Based Study ◽  
Competing Risk Models

Aim: To assess and predict risk and prognosis of lung cancer (LC) patients with second primary malignancy (SPM). Methods: LC patients diagnosed from 1992 to 2016 were obtained through the Surveillance, Epidemiology, and End Results database. Standardized incidence ratios were calculated to evaluate SPM risk. Cox regression and competing risk models were applied to assess the factors associated with overall survival, SPM development and LC-specific survival. Nomograms were built to predict SPM probability and overall survival. Results & conclusion: LC patients remain at higher risk of SPM even though the incidence declines. Patients with SPM have a better prognosis than patients without SPM. The consistency indexes for nomograms of SPM probability and overall survival are 0.605 (95% CI: 0.598–0.611) and 0.644 (95% CI: 0.638–0.650), respectively.

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