scholarly journals Long‐term use of low‐dose aspirin for cancer prevention: A 10‐year population cohort study in Hong Kong

2019 ◽  
Vol 145 (1) ◽  
pp. 267-273 ◽  
Author(s):  
Kelvin K.F. Tsoi ◽  
Jason M.W. Ho ◽  
Felix C.H. Chan ◽  
Joseph J.Y. Sung
Keyword(s):  
Cohort Study ◽  
Hong Kong ◽  
Cancer Prevention ◽  
Low Dose ◽  
Dose Aspirin ◽  
Population Cohort ◽  
Low Dose Aspirin ◽  
Population Cohort Study

scholarly journals Effect of low-dose aspirin use on pancreatic cancer development and morphological changes on imaging in IPMN: A long-term cohort study

2017 ◽  
Vol 5 (7) ◽  
pp. 1030-1036 ◽  
Author(s):  
Yusuke Takasaki ◽  
Naoyoshi Nagata ◽  
Koh Imbe ◽  
Yuya Hisada ◽  
Katsunori Sekine ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Cohort Study ◽  
Low Dose ◽  
Morphological Changes ◽  
Cancer Development ◽  
Dose Aspirin ◽  
Low Dose Aspirin

scholarly journals Association Between Aspirin Use and Decreased Risk of Pneumonia in Patients With Cardio-Cerebra-Vascular Ischemic Disease: A Population-Based Cohort Study

2021 ◽  
Vol 9 ◽  
Author(s):  
Ying-Cheng Chen ◽  
Yin-Yang Chen ◽  
Han Wei Yeh ◽  
Tung-Ying Yeh ◽  
Jing-Yang Huang ◽  
...  
Keyword(s):  
Cohort Study ◽  
Low Dose ◽  
Population Based ◽  
Hazard Ratio ◽  
Cumulative Probability ◽  
Research Database ◽  
Cox Regression Analysis ◽  
Dose Aspirin ◽  
Low Dose Aspirin

This study evaluated the association between long-term low-dose aspirin use and decreased risk of pneumonia in patients with cardio-cerebra-vascular ischemic diseases (CCVDs). This retrospective cohort study used records from Taiwan's National Health Insurance Research Database of claims made between 1997 and 2013. After propensity score matching (PSM), patients who took a low dose of aspirin for more than 90 days within 1 year of diagnosis with CCVDs were identified as the exposure group (n = 15,784). A matched total of 15,784 individuals without aspirin use were selected for the non-aspirin group. The main outcome was the development of pneumonia after the index date. Multivariable Cox regression analysis and Kaplan–Meier survival analysis were performed to estimate the adjusted hazard ratio (aHR) and cumulative probability of pneumonia. The result after PSM indicated a lower hazard ratio for pneumonia in aspirin users (aHR = 0.890, 95% confidence interval = 0.837–0.945). Therefore, patients with CCVDs who took aspirin had a lower risk of developing pneumonia than those who did not. In conclusion, this population-based cohort study demonstrated that long-term low-dose aspirin use is associated with a slightly decreased risk of pneumonia in patients with CCVDs.

scholarly journals Long-Term Low-Dose Aspirin Use Reduces Gastric Cancer Incidence: A Nationwide Cohort Study

2016 ◽  
Vol 48 (2) ◽  
pp. 798-805 ◽  
Author(s):  
Young-Il Kim ◽  
So Young Kim ◽  
Ji Hyun Kim ◽  
Jun Ho Lee ◽  
Young-Woo Kim ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cohort Study ◽  
Cancer Incidence ◽  
Low Dose ◽  
Dose Aspirin ◽  
Low Dose Aspirin

102 Resumption of Low-Dose Aspirin and the Risk of Recurrent Lower GI Bleeding and CV Outcomes: A Long-Term Cohort Study

2014 ◽  
Vol 146 (5) ◽  
pp. S-27 ◽  
Author(s):  
Francis K.L. Chan ◽  
En-Ling Leung Ki ◽  
Yee Kit Tse ◽  
Kim WL Au ◽  
Jessica Ching ◽  
...  
Keyword(s):  
Cohort Study ◽  
Low Dose ◽  
Gi Bleeding ◽  
Dose Aspirin ◽  
Low Dose Aspirin ◽  
Lower Gi Bleeding

scholarly journals Is Long-Term Low-Dose Aspirin Therapy Associated with Renal Dysfunction in Patients with Type 2 Diabetes? JPAD2 Cohort Study

PLoS ONE ◽  
2016 ◽  
Vol 11 (1) ◽  
pp. e0147635 ◽  
Author(s):  
Sadanori Okada ◽  
Takeshi Morimoto ◽  
Hisao Ogawa ◽  
Mio Sakuma ◽  
Hirofumi Soejima ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Cohort Study ◽  
Renal Dysfunction ◽  
Low Dose ◽  
Aspirin Therapy ◽  
Dose Aspirin ◽  
Low Dose Aspirin

T1958 Recurrent Ulcer Bleeding with Use of Low-Dose Aspirin After Eradication of H. pylori: An 8-Year Prospective Cohort Study

2009 ◽  
Vol 136 (5) ◽  
pp. A-609
Author(s):  
Francis K.L. Chan ◽  
Jessica Ching ◽  
Bing Yee Suen ◽  
Justin Wu ◽  
Vincent W. Wong ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Low Dose ◽  
Ulcer Bleeding ◽  
Recurrent Ulcer ◽  
Dose Aspirin ◽  
Low Dose Aspirin ◽  
H Pylori

scholarly journals Effects of low-dose aspirin on the osseointegration process in rats

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Ana Carolina Lupepsa ◽  
Paula Vargas-Sanchez ◽  
Marcella Goetz Moro ◽  
Leomar Emanuel Almeida Mecca ◽  
Marcela Claudino ◽  
...  
Keyword(s):  
Low Dose ◽  
Inhibitory Effect ◽  
Control Group ◽  
Implant Placement ◽  
Dose Aspirin ◽  
Low Dose Aspirin ◽  
Male Wistar Rats ◽  
Bone To Implant Contact ◽  
Bone Deposition

Abstract Background Several drugs are capable of promoting changes in bone metabolism. The aim of this study was to evaluate the effect of long-term low-dose aspirin (LDA) therapy on implant osseointegration. Methods Male Wistar rats were divided into 4 groups (n = 8/group) according to oral gavage solution received prior (42 days) to the implant surgery on the tibia. The control group was treated with saline solution for 7 (CG-7) and 28 (CG-28) days. The use of low-dose aspirin was performed in AG groups (6.75 mg/kg of aspirin) for 7 (AG-7) and 28 (AG-28) days. After experimental periods, histomorphometric evaluation of bone-to-implant contact (BIC) and the bone area between threads (BABT) was performed. Results Reduced BIC values were detected in AG-7 (62.8% ± 17.1) group compared to AG-28 (91.9% ± 5.4), CG-7 (82.7% ± 15.2), and CG-28 (89.9% ± 9.7). BABT evaluation revealed lower values in AG-7 (70.9% ± 15.2) compared to AG-28 (95.4% ± 3.7) and CG-28 (87.1% ± 10.2) groups. Conclusions The treatment with low doses of aspirin promoted a discrete inhibitory effect in the early stages (7 days) of repair after implant placement, specifically in the bone deposition. However, these effects were not detected in the late stages (28 days), considering BIC and BABT parameters.

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