scholarly journals Coffee and pancreatic cancer risk among never‐smokers in the UK prospective Million Women Study

2018 ◽  
Vol 145 (6) ◽  
pp. 1484-1492 ◽  
Author(s):  
Charlie D Zhou ◽  
Ai Seon Kuan ◽  
Gillian K Reeves ◽  
Jane Green ◽  
Sarah Floud ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Risk ◽  
Pancreatic Cancer Risk ◽  
Never Smokers ◽  
The Uk

scholarly journals Traditional and Novel Adiposity Indicators and Pancreatic Cancer Risk: Findings from the UK Women’s Cohort Study

Cancers ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1036
Author(s):  
Sangeetha Shyam ◽  
Darren Greenwood ◽  
Chun-Wai Mai ◽  
Seok Shin Tan ◽  
Barakatun Nisak Mohd Yusof ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Cohort Study ◽  
Cancer Risk ◽  
Reverse Causality ◽  
Hip Circumference ◽  
Primary Analysis ◽  
Pancreatic Cancer Risk ◽  
Obesity Indices ◽  
The Uk

(1) Background: We studied the association of both conventional (BMI, waist and hip circumference and waist–hip ratio) and novel (UK clothing sizes) obesity indices with pancreatic cancer risk in the UK women’s cohort study (UKWCS). (2) Methods: The UKWCS recruited 35,792 women from England, Wales and Scotland from 1995 to 1998. Cancer diagnosis and death information were obtained from the National Health Service (NHS) Central Register. Cox’s proportional hazards regression was used to evaluate the association between baseline obesity indicators and pancreatic cancer risk. (3) Results: This analysis included 35,364 participants with a median follow-up of 19.3 years. During the 654,566 person-years follow up, there were 136 incident pancreatic cancer cases. After adjustments for age, smoking, education and physical activity, each centimetre increase in hip circumference (HR: 1.03, 95% CI: 1.01–1.05, p = 0.009) and each size increase in skirt size (HR: 1.12, 95% CI: 1.02–1.23, p = 0.041) at baseline increased pancreatic cancer risk. Baseline BMI became a significant predictor of pancreatic cancer risk (HR: 1.04, 95% CI: 1.00–1.08, p = 0.050) when latent pancreatic cancer cases were removed. Only baseline hip circumference was associated with pancreatic cancer risk (HR: 1.03, 95% CI: 1.00–1.05, p = 0.017) when participants with diabetes at baseline were excluded to control for reverse causality. (4) Conclusion: Hip circumference and skirt size were significant predictors of pancreatic cancer risk in the primary analysis. Thus, hip circumference is useful to assess body shape relationships. Additionally, standard skirt sizes offer an economical and objective alternative to conventional obesity indices for evaluating pancreatic cancer risk in women.

Identification of genetic variants in m6A modification genes associated with pancreatic cancer risk in the Chinese population

2021 ◽  
Vol 95 (3) ◽  
pp. 1117-1128
Author(s):  
Pingting Ying ◽  
Yao Li ◽  
Nan Yang ◽  
Xiaoyang Wang ◽  
Haoxue Wang ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Risk ◽  
Genetic Variants ◽  
Chinese Population ◽  
Pancreatic Cancer Risk

scholarly journals MDM2 Promoter Polymorphism and Pancreatic Cancer Risk and Prognosis

2008 ◽  
Vol 14 (12) ◽  
pp. 4010-4015 ◽  
Author(s):  
Kofi Asomaning ◽  
Amy E. Reid ◽  
Wei Zhou ◽  
Rebecca S. Heist ◽  
Rihong Zhai ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Risk ◽  
Promoter Polymorphism ◽  
Pancreatic Cancer Risk

The oral microbiome in relation to pancreatic cancer risk in African Americans

2021 ◽  
Author(s):  
Jessica L. Petrick ◽  
Jeremy E. Wilkinson ◽  
Dominique S. Michaud ◽  
Qiuyin Cai ◽  
Hanna Gerlovin ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
African Americans ◽  
Cancer Risk ◽  
Oral Microbiome ◽  
Pancreatic Cancer Risk
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