scholarly journals Dietary folate intake and pancreatic cancer risk: Results from the European prospective investigation into cancer and nutrition

2018 ◽  
Vol 144 (7) ◽  
pp. 1511-1521 ◽  
Author(s):  
Jin Young Park ◽  
H. Bas Bueno‐de‐Mesquita ◽  
Pietro Ferrari ◽  
Elisabete Weiderpass ◽  
Jordi Batlle ◽  
...  
2014 ◽  
Vol 107 (1) ◽  
pp. dju367-dju367 ◽  
Author(s):  
J. de Batlle ◽  
P. Ferrari ◽  
V. Chajes ◽  
J. Y. Park ◽  
N. Slimani ◽  
...  

Author(s):  
Winta Yellow ◽  
William R. Bamlet ◽  
Ann L. Oberg ◽  
Kristin E. Anderson ◽  
Janet E. Olson ◽  
...  

Pancreatic cancer is one of the most fatal common cancers affecting both men and women, representing about 3 percent of all new cancer cases in the United States. In this study, we aimed to investigate the association of pancreatic cancer risk with alcohol consumption as well as folate intake. We performed a case-control study of 384 patients diagnosed with pancreatic cancer from May 2004 to December 2009 and 983 primary care healthy controls. Our findings showed no significant association between risk of pancreatic cancer and either overall alcohol consumption or type of alcohol consumed (drinks/day). Our study showed dietary folate intake was modestly but significantly inversely associated with pancreatic cancer (OR=0.99, P <.0001). The current study supports the hypothesis that pancreatic cancer risk is reduced with higher food-based folate intake.


2012 ◽  
Vol 131 (7) ◽  
pp. E1134-E1147 ◽  
Author(s):  
Esther Molina-Montes ◽  
Petra A. Wark ◽  
María-José Sánchez ◽  
Teresa Norat ◽  
Paula Jakszyn ◽  
...  

2011 ◽  
Vol 108 (3) ◽  
pp. 552-569 ◽  
Author(s):  
Jin Young Park ◽  
Genevieve Nicolas ◽  
Heinz Freisling ◽  
Carine Biessy ◽  
Augustin Scalbert ◽  
...  

Folate plays an important role in the synthesis and methylation of DNA as a cofactor in one-carbon metabolism. Inadequate folate intake has been linked to adverse health events. However, comparable information on dietary folate intake across European countries has never been reported. The objective of the present study was to describe the dietary folate intake and its food sources in ten countries in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. A cross-sectional analysis was conducted in 36 034 participants (aged 35–74 years) who completed a single 24 h dietary recall using a computerised interview software program, EPIC-Soft® (International Agency for Research on Cancer, Lyon). Dietary folate intake was estimated using the standardised EPIC Nutrient DataBase, adjusted for age, energy intake, weight and height and weighted by season and day of recall. Adjusted mean dietary folate intake in most centres ranged from 250 to 350 μg/d in men and 200 to 300 μg/d in women. Folate intake tended to be lower among current smokers and heavier alcohol drinkers and to increase with educational level, especially in women. Supplement users (any types) were likely to report higher dietary folate intake in most centres. Vegetables, cereals and fruits, nuts and seeds were the main contributors to folate intake. Nonetheless, the type and pattern of consumption of these main food items varied across the centres. These first comparisons of standardised dietary folate intakes across different European populations show moderate regional differences (except the UK health conscious group), and variation by sex, educational level, smoking and alcohol-drinking status, and supplement use.


2013 ◽  
Vol 24 (10) ◽  
pp. 2645-2651 ◽  
Author(s):  
M. Obón-Santacana ◽  
N. Slimani ◽  
L. Lujan-Barroso ◽  
N. Travier ◽  
G. Hallmans ◽  
...  

2011 ◽  
Vol 47 (12) ◽  
pp. 1808-1816 ◽  
Author(s):  
Shu-Chun Chuang ◽  
Rachael Stolzenberg-Solomon ◽  
Per Magne Ueland ◽  
Stein Emil Vollset ◽  
Øivind Midttun ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document