scholarly journals DS-8201a, a new HER2-targeting antibody-drug conjugate incorporating a novel DNA topoisomerase I inhibitor, overcomes HER2-positive gastric cancer T-DM1 resistance

2017 ◽  
Vol 141 (8) ◽  
pp. 1682-1689 ◽  
Author(s):  
Naoki Takegawa ◽  
Yoshikane Nonagase ◽  
Kimio Yonesaka ◽  
Kazuko Sakai ◽  
Osamu Maenishi ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Topoisomerase I ◽  
Dna Topoisomerase I ◽  
Antibody Drug Conjugate ◽  
Her2 Positive ◽  
Dna Topoisomerase ◽  
Topoisomerase I Inhibitor ◽  
Drug Conjugate ◽  
Antibody Drug

scholarly journals Phase 1 study of bispecific HER2 antibody-drug conjugate MEDI4276 in patients with advanced HER2-positive breast or gastric cancer

2018 ◽  
Vol 29 ◽  
pp. iii8 ◽  
Author(s):  
M. Pegram ◽  
E. Hamilton ◽  
A.R. Tan ◽  
A.M. Storniolo ◽  
N. Elgeioushi ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Phase 1 ◽  
Antibody Drug Conjugate ◽  
Her2 Positive ◽  
Phase 1 Study ◽  
Drug Conjugate ◽  
Antibody Drug
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