The national landscape of human papillomavirus-associated oropharynx squamous cell carcinoma

2016 ◽  
Vol 140 (3) ◽  
pp. 504-512 ◽  
Author(s):  
Erik Liederbach ◽  
Alexandra Kyrillos ◽  
Chi-Hsiung Wang ◽  
Jeffrey C. Liu ◽  
Erich M. Sturgis ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Human Papillomavirus ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Oropharynx Squamous Cell Carcinoma

scholarly journals Correlation between koilocytes and human papillomavirus detection by PCR in oral and oropharynx squamous cell carcinoma biopsies

2011 ◽  
Vol 106 (2) ◽  
pp. 166-169 ◽  
Author(s):  
Glauco Issamu Miyahara ◽  
Luciana Estevam Simonato ◽  
Neivio José Mattar ◽  
Deolino João Camilo Jr ◽  
Eder Ricardo Biasoli
Keyword(s):  
Squamous Cell Carcinoma ◽  
Human Papillomavirus ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Oropharynx Squamous Cell Carcinoma

scholarly journals Concurrent Human Papillomavirus-Positive Squamous Cell Carcinoma of the Oropharynx in a Married Couple

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Tyler D. Brobst ◽  
Joaquín J. García ◽  
Katharine A. Price ◽  
Ge Gao ◽  
David I. Smith ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Human Papillomavirus ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Married Couple ◽  
Oropharynx Squamous Cell Carcinoma ◽  
High Risk Hpv ◽  
Tumor Biopsies

Background. Although alcohol and tobacco use are known risk factors for development of squamous cell carcinoma in the head and neck, human papillomavirus (HPV) has been increasingly associated with this group of cancers. We describe the case of a married couple who presented with HPV-positive oropharynx squamous cell carcinoma within two months of each other.Methods. Tumor biopsies were positive for p16 and high-risk HPV in both patients. Sanger sequencing showed a nearly identical HPV16 strain in both patients. Both patients received chemoradiation, and one patient also underwent transoral robotic tongue base resection with bilateral neck dissection.Results. Both patients showed no evidence of recurrent disease on follow-up PET imaging.Conclusions. New head and neck symptoms should be promptly evaluated in the partner of a patient with known HPV-positive oropharynx cancer. This case expands the limited current literature on concurrent presentation of HPV-positive oropharynx squamous cell carcinoma in couples.

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