scholarly journals Circulating CUDR, LSINCT-5 and PTENP1 long noncoding RNAs in sera distinguish patients with gastric cancer from healthy controls

2015 ◽  
Vol 137 (5) ◽  
pp. 1128-1135 ◽  
Author(s):  
Lei Dong ◽  
Peng Qi ◽  
Mi-Die Xu ◽  
Shu-Juan Ni ◽  
Dan Huang ◽  
...  
Oncotarget ◽  
2016 ◽  
Vol 7 (8) ◽  
pp. 8601-8612 ◽  
Author(s):  
Tianwen Li ◽  
Xiaoyan Mo ◽  
Liyun Fu ◽  
Bingxiu Xiao ◽  
Junming Guo

2019 ◽  
Vol Volume 11 ◽  
pp. 6175-6184 ◽  
Author(s):  
Ziwei Yang ◽  
Yanfei Sun ◽  
Rongfeng Liu ◽  
Yanyan Shi ◽  
Shigang Ding

Epigenomics ◽  
2018 ◽  
Vol 10 (4) ◽  
pp. 433-443 ◽  
Author(s):  
Jian Zhang ◽  
Yujie Yuan ◽  
Zhewei Wei ◽  
Jianwei Ren ◽  
Xun Hou ◽  
...  

2018 ◽  
Vol Volume 11 ◽  
pp. 4877-4891 ◽  
Author(s):  
Song Gao ◽  
Zhi-Ying Zhao ◽  
Rong Wu ◽  
Yue Zhang ◽  
Zhen-Yong Zhang

2021 ◽  
Vol 2021 ◽  
pp. 1-14
Author(s):  
Jiao Guo ◽  
Yongda Liu ◽  
Ping Zhao

Gastric cancer (GC) is the fifth most common malignant tumor in the world. The present study was performed to discover the potential diagnostic and therapeutic long noncoding RNAs (lncRNAs) and microRNAs (miRNAs) of GC. Data used in this study to identify differentially expressed lncRNAs (DElncRNAs) and miRNAs (DEmiRNAs) were obtained from 187 GC tissues and 32 adjacent nontumor tissues. The total clinical data on GC included 187 cases. The above data were from the TCGA database. RStudio/Bioconductor software was used to conduct univariate analysis, the least absolute shrinkage and selection operator (LASSO) Cox, and multivariate Cox proportional risk regression for the DElncRNAs and DEmiRNAs. Clinical information was analyzed through univariate and multivariate Cox analysis. Results: five lncRNAs (AC007785.3, AC079385.3, LINC00392, LINC01729, and U95743.1) and two miRNAs (hsa-miR-3174, hsa-miR-605) were proven to be independent prognostic indicators of GC. Results of the Kaplan-Meier survival analysis showed that AC007785.3, AC079385.3, LINC01729, miR-3174, and miR-605 were significantly correlated with OS of GC. The target genes of AC079385.3, miR-3174, and miR-605 were obtained and clustered mainly on MAPK and cGMP-PKG signaling pathways. The clinical data showed that age and clinicopathologic stage were correlated with the prognosis of GC. Furthermore, AC007785.3 was associated with metastasis of GC, and miR-3174 was associated with the primary tumor condition of GC. We identified three lncRNAs (AC007785.3, AC079385.3, LINC01729), two miRNAs (miR-3174, miR-605), and clinical factors related to the pathogenesis and prognosis of GC. Our predicted results provide a possible entry point for the study of prognostic markers for GC.


2016 ◽  
pp. 681 ◽  
Author(s):  
Zhenning Wang ◽  
Jiajun Wang ◽  
Jun Wang ◽  
Yongxi Song ◽  
Peng Gao ◽  
...  

Gene ◽  
2019 ◽  
Vol 687 ◽  
pp. 135-142 ◽  
Author(s):  
Hamid Ghaedi ◽  
Mohammad Amin Nazer Mozaffari ◽  
Zaker Salehi ◽  
Hassan Ghasemi ◽  
Seyed Sajjad Zadian ◽  
...  

2019 ◽  
Vol 120 (8) ◽  
pp. 13802-13809 ◽  
Author(s):  
Farbod Esfandi ◽  
Mohammad Taheri ◽  
Vahid Kholghi Oskooei ◽  
Soudeh Ghafouri‐Fard

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