scholarly journals The high prevalence of undiagnosed prostate cancer at autopsy: implications for epidemiology and treatment of prostate cancer in the Prostate-specific Antigen-era

2015 ◽  
Vol 137 (12) ◽  
pp. 2795-2802 ◽  
Author(s):  
Jaquelyn L. Jahn ◽  
Edward L. Giovannucci ◽  
Meir J. Stampfer
Keyword(s):  
Prostate Cancer ◽  
Prostate Specific Antigen ◽  
Specific Antigen ◽  
High Prevalence

scholarly journals Current Challenges in Prostate Cancer Management and the Rationale behind Targeted Focal Therapy

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Al B. Barqawi ◽  
Kevin J. Krughoff ◽  
Khadijah Eid
Keyword(s):  
Prostate Cancer ◽  
Prostate Specific Antigen ◽  
Specific Antigen ◽  
Focal Therapy ◽  
Current Treatment ◽  
Cancer Awareness ◽  
Cancer Statistics ◽  
Cancer Management ◽  
Treatment Techniques ◽  
High Prevalence

Among men, prostate cancer has a high prevalence, with relatively lower cancer-specific mortality risk compared to lung and colon cancer. Prostate-specific antigen (PSA) screening has increased prostate cancer awareness since its implementation as a screening tool almost 25 years ago, but, due to the largely indolent course of this disease and the unspecific nature of the PSA test, increased incidence has largely been associated with cancers that would not go on to cause death (clinically insignificant), leading to an overdiagnosis challenge and an ensuing overtreatment consequences. The overtreatment problem is exacerbated by the high risk of side effects that current treatment techniques have, putting patients’ quality of life at risk with little or no survival benefit. The goals of this paper are to evaluate the rise, prevalence, and impact of the overdiagnosis and ensuing overtreatment problems, as well as highlight potential solutions. In this effort, a review of major epidemiological and screening studies, cancer statistics from the advent of prostate-specific antigen screening to the present, and reports on patient concerns and treatment outcomes was conducted to present the dominant factors that underlie current challenges in prostate cancer treatment and illuminate potential solutions.

1267: Prostate-Specific Antigen Velocity among African-American and White Men Without Prostate Cancer

2004 ◽  
Vol 171 (4S) ◽  
pp. 334-334
Author(s):  
Walter J. Simoneaux ◽  
Caleb B. Bozeman ◽  
Brett S. Carver ◽  
Donald A. Elmajian
Keyword(s):  
Prostate Cancer ◽  
African American ◽  
Prostate Specific Antigen ◽  
Specific Antigen ◽  
White Men

1662: Volume-Based Evaluation of the Ratio of Precursor Prostate-Specific Antigen Isoforms in the Detection of Prostate Cancer

2004 ◽  
Vol 171 (4S) ◽  
pp. 439-440
Author(s):  
Yoshio Naya ◽  
Herbert A. Fritsche ◽  
Viju A. Bhadkamkar ◽  
Stephen D. Mikolajczyk ◽  
Harry G. Rittenhouse ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Prostate Specific Antigen ◽  
Specific Antigen
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