Human papillomavirus in vulvar squamous-cell carcinoma and in normal vulvar tissues: A search for a possible impact of HPV on vulvar cancer prognosis

1993 ◽  
Vol 55 (3) ◽  
pp. 394-396 ◽  
Author(s):  
Ulla Hørding ◽  
Johannes E. Bock ◽  
Birgitte Kringsholm ◽  
Benny Andreasson ◽  
Jakob Visfeldt ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Human Papillomavirus ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Vulvar Cancer ◽  
Cancer Prognosis ◽  
Vulvar Squamous Cell Carcinoma

Human papillomavirus and herpes simplex virus in vulvar squamous cell carcinoma in situ

1988 ◽  
Vol 158 (4) ◽  
pp. 862-869 ◽  
Author(s):  
Raymond H. Kaufman ◽  
Jacob Bornstein ◽  
Ervin Adam ◽  
Joyce Burek ◽  
Barbara Tessin ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Human Papillomavirus ◽  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Carcinoma In Situ ◽  
Vulvar Squamous Cell Carcinoma ◽  
Simplex Virus

Presence of human papillomavirus (HPV) in vulvar squamous cell carcinoma (VSCC) and sentinel node

2010 ◽  
Vol 117 (2) ◽  
pp. 312-316 ◽  
Author(s):  
Gunnel Lindell ◽  
Anders Näsman ◽  
Cathrine Jonsson ◽  
Radmila Jovanovic Ehrsson ◽  
Hans Jacobsson ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Human Papillomavirus ◽  
Sentinel Node ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Vulvar Squamous Cell Carcinoma

scholarly journals A Case of Stage I Vulvar Squamous Cell Carcinoma with Early Relapse and Rapid Disease Progression

2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
Marta Peri ◽  
Antonino Grassadonia ◽  
Laura Iezzi ◽  
Patrizia Vici ◽  
Michele De Tursi ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Early Diagnosis ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Vulvar Cancer ◽  
Early Stage ◽  
Vulvar Squamous Cell Carcinoma ◽  
Rapid Disease Progression ◽  
Early Relapse ◽  
Dismal Prognosis

Squamous cell carcinoma (SCC) is the most common subtype of vulvar cancer. Locoregional surgery is often curative when the tumor is diagnosed at an early stage. However, the disease can unexpectedly evolve with a dismal prognosis even after an early diagnosis. We report a case of a woman who experienced a rapid, chemorefractory tumor progression after surgery for stage IB vulvar SCC.

Does human papillomavirus infection imply a different prognosis in vulvar squamous cell carcinoma?

2011 ◽  
Vol 122 (3) ◽  
pp. 509-514 ◽  
Author(s):  
Immaculada Alonso ◽  
Victoria Fusté ◽  
Marta del Pino ◽  
Paola Castillo ◽  
Aureli Torné ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Human Papillomavirus ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Vulvar Squamous Cell Carcinoma ◽  
Human Papillomavirus Infection ◽  
Papillomavirus Infection

scholarly journals Indocyanine green fluorescence imaging, sentinel lymph node mapping in patients with vulvar cancer: peritumoral injection dosage and waiting times in our experience

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
P. Scollo ◽  
M. Ferrara ◽  
B. Pecorino ◽  
A. B. Di Stefano ◽  
G. Scibilia
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Lymph Nodes ◽  
Indocyanine Green ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Vulvar Cancer ◽  
Maximum Diameter ◽  
Vulvar Squamous Cell Carcinoma

Abstract Background Vulvar cancer is a rare gynecological malignancy that primarily affects women of postmenopausal age. Treatment is mainly surgical, particularly for vulvar squamous cell carcinoma, the most prevalent histotype. In patients with unifocal tumors with a maximum diameter of <4 cm, in the absence of suspected inguinal lymph nodes, sentinel lymph node (SLN) biopsy is recommended. The use of a radioactive tracer is mandatory; the use of the vital blue dye is optional. Results Two patients diagnosed with vulvar squamous cell carcinoma (FIGO IB stage) underwent bilateral radical vulvectomy, SLN search and removal, and bilateral inguinal lymphadenectomy at the Cannizzaro Hospital Operative Unit of Obstetrics and Gynecology Department (Catania, Italy). Three milliliters of indocyanine green (ICG) 0.5 mg/mL was administered in 3 peritumoral injections under general anesthesia to screen the SLN. The images were acquired using an intraoperative infrared camera system, which allowed intraoperative visualization of the SLN. An SLN was identified for each patient. The lymph nodes examined by the pathologist were negative for metastatic localization of the disease. However, patients underwent bilateral inguinofemoral lymphadenectomy, as this procedure is not currently codified as a gold standard for the detection of SLN in vulvar cancer. All the lymph nodes removed were negative for the localization of vulvar carcinoma metastases. Conclusions The potential of the administration of indocyanine green (ICG) allows the execution of SLN biopsy, avoiding the multiple administrations of radiocolloid in the pre-operative phase, painful for the patient, elimination, and exposure to radioactivity. Therefore, while requiring standardization of the methodology and a large-scale application, this procedure could open a new surgical management perspective in patients with early-stage vulvar cancer.

scholarly journals HPV-Negative Vulvar Squamous Cell Carcinoma in a 21-year-old Patient

2021 ◽  
pp. 36
Author(s):  
Keyword(s):  
Risk Factors ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Rare Case ◽  
Vulvar Cancer ◽  
Hpv Infection ◽  
Adjuvant Radiation ◽  
Vulvar Squamous Cell Carcinoma ◽  
Adjuvant Radiation Therapy

Vulvar Squamous Cell Carcinoma usually occurs among women in their 60s or 70s. There are a limited number of reports of vulvar cancer cases younger than 30 years. These patients have usually risk factors such as human papillomavirus (HPV) infection. In this report, the authors present a rare case of invasive vulvar squamous cell carcinoma in a 21-year-old patient without HPV infection. Surgical treatment was performed, followed by adjuvant radiation therapy.

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