Evaluation of epstein-barr virus-associated nuclear antigen with various human cell lines

1974 ◽  
Vol 14 (6) ◽  
pp. 753-761 ◽  
Author(s):  
Masahiro Suzuki ◽  
Yorio Hinuma
Keyword(s):  
Cell Lines ◽  
Human Cell ◽  
Epstein Barr Virus ◽  
Nuclear Antigen ◽  
Human Cell Lines ◽  
Barr Virus ◽  
Epstein Barr

scholarly journals Increased myeloid-associated enzymes in Epstein-Barr virus nuclear antigen--positive human cell lines exposed to butyric acid in vitro

Blood ◽  
1978 ◽  
Vol 51 (6) ◽  
pp. 1073-1085 ◽  
Author(s):  
JS Greenberger ◽  
A Karpas ◽  
PJ Gans ◽  
H Neumann ◽  
WC Moloney
Keyword(s):  
Cell Lines ◽  
Butyric Acid ◽  
Human Cell ◽  
Epstein Barr Virus ◽  
Nuclear Antigen ◽  
Human Cell Lines ◽  
Barr Virus ◽  
Epstein Barr

Antibody to human cell lines with and without ultrastructural evidence for epstein-barr virus (ebv) infection in sera from patients with diverse viral illnesses

1971 ◽  
Vol 7 (3) ◽  
pp. 375-379 ◽  
Author(s):  
German Beltran ◽  
James W. Northington ◽  
Eduardo Leiderman ◽  
William J. Mogabgab ◽  
Walter J. Stuckey
Keyword(s):  
Cell Lines ◽  
Human Cell ◽  
Epstein Barr Virus ◽  
Human Cell Lines ◽  
Barr Virus ◽  
Ebv Infection ◽  
Ultrastructural Evidence ◽  
Epstein Barr

scholarly journals Comprehensive profiling of functional Epstein-Barr virus miRNA expression in human cell lines

BMC Genomics ◽  
2016 ◽  
Vol 17 (1) ◽  
Author(s):  
Marjolein J. G. Hooykaas ◽  
Elisabeth Kruse ◽  
Emmanuel J. H. J. Wiertz ◽  
Robert Jan Lebbink
Keyword(s):  
Cell Lines ◽  
Human Cell ◽  
Mirna Expression ◽  
Epstein Barr Virus ◽  
Human Cell Lines ◽  
Barr Virus ◽  
Epstein Barr

Interactions between Epstein-Barr Virus (EBV) and Human Cell Lines: Growth and EBV Induction

ORL ◽  
1990 ◽  
Vol 52 (1) ◽  
pp. 40-46 ◽  
Author(s):  
T. Takimoto ◽  
J. Iwawaki ◽  
S. Tanaka ◽  
R. Umeda
Keyword(s):  
Cell Lines ◽  
Human Cell ◽  
Epstein Barr Virus ◽  
Human Cell Lines ◽  
Barr Virus ◽  
Epstein Barr

scholarly journals Differences in human cell lines to support stable replication of Epstein-Barr virus-based vectors

1990 ◽  
Vol 1048 (2-3) ◽  
pp. 171-177 ◽  
Author(s):  
Miguel Vidal ◽  
Christopher Wrighton ◽  
Sarah Eccles ◽  
Julian Burke ◽  
Frank Grosveld
Keyword(s):  
Cell Lines ◽  
Human Cell ◽  
Epstein Barr Virus ◽  
Human Cell Lines ◽  
Barr Virus ◽  
Epstein Barr

scholarly journals Characterization of naturally Epstein–Barr virus-infected gastric carcinoma cell line YCCEL1

2013 ◽  
Vol 94 (3) ◽  
pp. 497-506 ◽  
Author(s):  
Do Nyun Kim ◽  
Min Koo Seo ◽  
Hoyun Choi ◽  
Su Yeon Kim ◽  
Hee Jong Shin ◽  
...  
Keyword(s):  
Cell Line ◽  
Cell Lines ◽  
Blot Analysis ◽  
Epstein Barr Virus ◽  
Model Systems ◽  
Nuclear Antigen ◽  
Gastric Carcinoma Cell ◽  
Barr Virus ◽  
Epstein Barr

Epstein–Barr virus (EBV) is a herpesvirus associated with lymphomas and carcinomas. While EBV-associated epithelial cell lines are good model systems to investigate the role of EBV in carcinoma, only a few cell lines are available as they are hard to acquire. A greater variety of naturally EBV-infected cell lines which are derived from tumour patients are needed to represent various features of EBVaGC. We characterized cell line YCCEL1, established from a Korean EBVaGC patient, to ascertain whether it can be used to study the roles of EBV in EBVaGC. The expression of EBV genes and cell surface markers was examined by in situ hybridization, RT-PCR, Western blot analysis, immunofluorescence assay and Northern blot analysis. EBV episomal status was analysed by Southern blotting and real-time PCR. This cell line expressed EBV nuclear antigen 1 (EBNA1) and latent membrane protein 2A (LMP2A), but not EBNA2, LMP2B nor LMP1. The majority of the lytic proteins were not detected in YCCEL1 cells either before or after treatment with 12-O-tetradecanoylphorbol-13-acetate. YCCEL1 cells expressed BART microRNAs (miRNAs) at high level but did not express BHRF1 miRNAs. YCCEL1 cells expressed cytokeratin, but not CD21 and CD19, suggesting CD21-independent EBV infection. The latent EBV gene and EBV miRNA expression pattern of YCCEL1 cells closely resembled that of general EBVaGC cases. Our results support the value of YCCEL1 cells as a good model system to study the role of EBV in gastric carcinogenesis.

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