HOXA9,ISL1andALDH1A3methylation patterns as prognostic markers for nonmuscle invasive bladder cancer: Array-based DNA methylation and expression profiling

2013 ◽  
Vol 133 (5) ◽  
pp. 1135-1142 ◽  
Author(s):  
Yong-June Kim ◽  
Hyung-Yoon Yoon ◽  
Ji Sang Kim ◽  
Ho Won Kang ◽  
Byung-Dal Min ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Bladder Cancer ◽  
Expression Profiling ◽  
Prognostic Markers ◽  
Invasive Bladder Cancer ◽  
Nonmuscle Invasive Bladder Cancer

Nonmuscle-Invasive Bladder Cancer: What's Changing and What has Changed

2017 ◽  
Vol 84 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Ramanitharan Manikandan ◽  
Oscar Rodriguez ◽  
Rubén Parada ◽  
Joan Palou Redorta
Keyword(s):  
Bladder Cancer ◽  
Best Practice ◽  
Disease Recurrence ◽  
Invasive Bladder Cancer ◽  
Current Status ◽  
Optimal Care ◽  
Medline Search ◽  
Select Group ◽  
The Future ◽  
Nonmuscle Invasive Bladder Cancer

Purpose Nonmuscle-invasive bladder cancer (NMIBC) is a challenging disease to manage primarily due to its varied clinical course. The management of NMIBC has witnessed a widespread change with respect to its diagnosis and treatment. Although transurethral resection (TUR) and adjuvant bacillus Calmette–Guerin (BCG) stills remain the cornerstone, newer protocols has come into vogue to achieve optimal care. On the basis of a literature review, we aimed to establish ‘what changes has already occurred and what is expected in the future’ in NMIBC. Methods A Medline search was performed to identify the published literature with respect to diagnosis, treatment and future perspectives on NMIBC. Particular emphasis was directed to determinants such as the quality of TUR and the newer modifications, Re-TUR, current status of newer macroscopic and microscopic imaging, role of urinary biomarkers, clinical, histologic and molecular predictors of high-risk disease, administration of intravesical agents, salvage therapy in BCG recurrence and the current best practice guidelines were analyzed. Results and Conclusions Optimal TUR, restaging in select group, incorporation of newer endoscopic imaging and judicious administration of intravesical chemo-immunotherapeutic agents can contribute to better patient care. Although there is a plethora of urinary markers, there is insufficient evidence for their use in isolation. The future probably lies in identification of genetic markers to determine disease recurrence, nonresponders to standard treatment and early institution of alternative/targeted therapy.

Hexylaminolevulinate Photodynamic Diagnosis for Multifocal Recurrent Nonmuscle Invasive Bladder Cancer

2009 ◽  
Vol 23 (6) ◽  
pp. 983-988 ◽  
Author(s):  
Eleanor R. Ray ◽  
Kathryn Chatterton ◽  
Kay Thomas ◽  
M. Shamim Khan ◽  
Ashish Chandra ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Invasive Bladder Cancer ◽  
Photodynamic Diagnosis ◽  
Nonmuscle Invasive Bladder Cancer

scholarly journals The long-term outcome of treated high-risk nonmuscle-invasive bladder cancer

Cancer ◽  
2012 ◽  
Vol 118 (22) ◽  
pp. 5525-5534 ◽  
Author(s):  
Francis Thomas ◽  
Derek J. Rosario ◽  
Naomi Rubin ◽  
John R. Goepel ◽  
Maysam F. Abbod ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
High Risk ◽  
Invasive Bladder Cancer ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Nonmuscle Invasive Bladder Cancer

scholarly journals Assessment of Pain Management, Acceptance of Illness, and Adjustment to Life with Cancer in Patients with Nonmuscle Invasive Bladder Cancer

2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
Wojciech Krajewski ◽  
Małgorzata Mazur ◽  
Adrian Poterek ◽  
Agata Pastuszak ◽  
Urszula Halska ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Pain Management ◽  
Coping Strategies ◽  
Psychological State ◽  
Invasive Bladder Cancer ◽  
Place Of Residence ◽  
Fighting Spirit ◽  
Acceptance Of Illness ◽  
And Coping ◽  
Nonmuscle Invasive Bladder Cancer

Purpose. According to the European Association of Urology bladder cancer is the seventh most commonly diagnosed malignancy in the world’s male population. Despite its high incidence, papers evaluating psychological state in those patients’ group are lacking. The purpose of the study was to evaluate pain management, disease acceptance, and adjustment to cancer in homogenous group of patients diagnosed with nonmuscle-invasive bladder cancer (NMIBC). Methods. Group of 252 male patients who were scheduled for NMIBC treatment were prospectively evaluated. Patients fulfilled Acceptance of Illness Scale (AIS), Mini-Mental Adjustment to Cancer (Mini-MAC) and Coping Strategies (CSQ) questionnaires before treatment introduction. Results. Highest CSQ score was achieved by the coping self-statements subscale (mean=18,37). The catastrophizing subscale score was the lowest (mean=11,24). Place of residence affected results of CSQ statement about pain control. Catastrophizing and coping self-statements strategies were associated with matrimonial status. In the Mini-MAC questionnaire the fighting spirit way of coping had the highest (21,73) and the helplessness-hopelessness subscale had the lowest mean value (13,3). Matrimonial status was strongly associated with anxious preoccupation, fighting spirit, and helplessness – hopelessness way of coping. The mean AIS test score was 28.8. AIS result was influenced by patient’s marital status, yet not by education, place of residence, nor any clinical factor. Conclusions. In the examined group, the level of acceptance of the disease reached values that were slightly higher than the average. It indicated a fairly good adaptation to cancer. Among the methods of coping with cancer, the constructive style is definitely dominant with a high intensity of the fighting spirit strategy. The destructive style of cancer coping reached low values with a low intensity of helplessness/hopelessness strategy. From pain coping strategies, self-statements and praying/hoping were the most commonly chosen ways, whereas catastrophizing was the rarest. Many associations between various questioners’ results were also observed.

Active Surveillance for Low Risk Nonmuscle Invasive Bladder Cancer: A Confirmatory and Resource Consumption Study from the BIAS Project

2018 ◽  
Vol 199 (2) ◽  
pp. 401-406 ◽  
Author(s):  
Rodolfo Hurle ◽  
Massimo Lazzeri ◽  
Elena Vanni ◽  
Giovanni Lughezzani ◽  
NicolòMaria Buffi ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Active Surveillance ◽  
Resource Consumption ◽  
Low Risk ◽  
Invasive Bladder Cancer ◽  
Nonmuscle Invasive Bladder Cancer
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