scholarly journals Chemopreventive effect of a novel oleanane triterpenoid in a chemically induced rodent model of breast cancer

2013 ◽  
Vol 133 (5) ◽  
pp. 1054-1063 ◽  
Author(s):  
Anupam Bishayee ◽  
Animesh Mandal ◽  
Roslin J. Thoppil ◽  
Altaf S. Darvesh ◽  
Deepak Bhatia
Keyword(s):  
Breast Cancer ◽  
Rodent Model ◽  
Chemically Induced ◽  
Chemopreventive Effect ◽  
Oleanane Triterpenoid

Resveratrol enhances the chemopreventive effect of celecoxib in chemically induced breast cancer in rats

2014 ◽  
Vol 23 (6) ◽  
pp. 506-513 ◽  
Author(s):  
Terézia Kisková ◽  
Rastislav Jendželovský ◽  
Erdenetsetsek Rentsen ◽  
Alexandra Maier-Salamon ◽  
Natália Kokošová ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Chemically Induced ◽  
Chemically Induced Breast Cancer ◽  
Chemopreventive Effect

The Chemopreventive Effect of Tamoxifen Combined with Celecoxib on DMBA chemically-Induced Breast Cancer

2007 ◽  
Vol 21 (2) ◽  
pp. 108-111 ◽  
Author(s):  
Xiaoxu Liu ◽  
Huafeng Kang ◽  
Xijing Wang ◽  
Zhijun Dai ◽  
Fengjie Xue ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Chemically Induced ◽  
Chemically Induced Breast Cancer ◽  
Chemopreventive Effect

scholarly journals Antioxidant and Chemopreventive Effect of Aliophen® Formulation Based on Malts and Hops

Antioxidants ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 29
Author(s):  
Idolo Tedesco ◽  
Carmela Spagnuolo ◽  
Stefania Bilotto ◽  
Angelo A. Izzo ◽  
Francesca Borrelli ◽  
...  
Keyword(s):  
Health Effects ◽  
Low Density Lipoprotein ◽  
Antioxidant Properties ◽  
Density Lipoprotein ◽  
Ldl Oxidation ◽  
Preneoplastic Lesions ◽  
Chemically Induced ◽  
Chemopreventive Effect ◽  
The One ◽  
Higher Doses

Experimental and clinical studies evidenced the health effects of moderate consumption of beer, mainly due to the presence of bioactive compounds, such as polyphenols, vitamins, or fibers. To exploit the potential beneficial effect on health and in disease prevention of these compounds, a new beverage based on barley malts and hops named Aliophen® has been designed, through a patented production process, with a high total polyphenolic amount compared to alcohol-free beer and similar to the one present in light and dark beers. In the present study, the antioxidant activity of Aliophen® against low-density lipoprotein (LDL) oxidation and its ability to protect erythrocytes from hemolysis have been characterized. Moreover, the chemopreventive effect of Aliophen® against colon cancer has been assessed, employing a mouse model of chemically induced carcinogenesis using azoxymethane (AOM). Data obtained showed that Aliophen at a low dose (3 mg/kg) inhibited the formation of preneoplastic lesions, polyps, and tumors. At higher doses (300 mg/kg) the protective effect was measured in the first phase of the onset of cancer. The antioxidant properties of Aliophen® were also observed in AOM-treated mice where it increased the serum antioxidant capacity. Based on the data presented, Aliophen® can exert promising health effects, including an anticancer capacity presumably associated with its antioxidant properties.

scholarly journals Metformin inhibits stromal aromatase expression and tumor progression in a rodent model of postmenopausal breast cancer

2018 ◽  
Vol 20 (1) ◽  
Author(s):  
Erin D. Giles ◽  
Sonali Jindal ◽  
Elizabeth A. Wellberg ◽  
Troy Schedin ◽  
Steven M. Anderson ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Tumor Progression ◽  
Postmenopausal Breast Cancer ◽  
Rodent Model ◽  
Aromatase Expression

scholarly journals Chemopreventive effect of dietary flavonoid morin on chemically induced rat tongue carcinogenesis

1999 ◽  
Vol 83 (3) ◽  
pp. 381-386 ◽  
Author(s):  
Kunihiro Kawabata ◽  
Takuji Tanaka ◽  
Shiro Honjo ◽  
Mikio Kakumoto ◽  
Akira Hara ◽  
...  
Keyword(s):  
Chemically Induced ◽  
Chemopreventive Effect ◽  
Dietary Flavonoid ◽  
Rat Tongue

A New Proposed Rodent Model of Chemically Induced Prostate Carcinogenesis: Distinct Time-Course Prostate Cancer Progression in the Dorsolateral and Ventral Lobes

The Prostate ◽  
2013 ◽  
Vol 73 (11) ◽  
pp. 1202-1213 ◽  
Author(s):  
Bianca F. Gonçalves ◽  
Silvana G.P. de Campos ◽  
Cristiani Zanetoni ◽  
Wellerson R. Scarano ◽  
Luiz R. Falleiros ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Progression ◽  
Time Course ◽  
Rodent Model ◽  
Prostate Cancer Progression ◽  
Prostate Carcinogenesis ◽  
Chemically Induced

Chemopreventive Effect of Brazilian Red Propolis on the Oral Carcinogenesis in Rodent Model

2015 ◽  
Vol 120 (2) ◽  
pp. e106 ◽  
Author(s):  
GABRYELLA NUNES DOS SANTOS ◽  
DANIELLE RODRIGUES RIBEIRO ◽  
ANGELA VALÉRIA FARIAS ALVES ◽  
ESAÚ PINHEIRO DOS SANTOS ◽  
JULIANA CORDEIRO CARDOSO ◽  
...  
Keyword(s):  
Rodent Model ◽  
Oral Carcinogenesis ◽  
Chemopreventive Effect

scholarly journals Advances in Rodent Models for Breast Cancer Formation, Progression, and Therapeutic Testing

2021 ◽  
Vol 11 ◽  
Author(s):  
Chong Liu ◽  
Pei Wu ◽  
Ailin Zhang ◽  
Xiaoyun Mao
Keyword(s):  
Breast Cancer ◽  
Cancer Progression ◽  
Rodent Model ◽  
Rodent Models ◽  
Clinical Therapeutics ◽  
Advantages And Disadvantages ◽  
Treatment And Prevention ◽  
Mechanism Of Carcinogenesis ◽  
Prevention Of Breast Cancer ◽  
Selection Of

Breast cancer is a highly complicated disease. Advancement in the treatment and prevention of breast cancer lies in elucidation of the mechanism of carcinogenesis and progression. Rodent models of breast cancer have developed into premier tools for investigating the mechanisms and genetic pathways in breast cancer progression and metastasis and for developing and evaluating clinical therapeutics. Every rodent model has advantages and disadvantages, and the selection of appropriate rodent models with which to investigate breast cancer is a key decision in research. Design of a suitable rodent model for a specific research purpose is based on the integration of the advantages and disadvantages of different models. Our purpose in writing this review is to elaborate on various rodent models for breast cancer formation, progression, and therapeutic testing.

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