Relationship between sunbed use and melanoma risk in a large case-control study in the United Kingdom

2011 ◽  
Vol 130 (12) ◽  
pp. 3011-3013 ◽  
Author(s):  
Faye Elliott ◽  
Mariano Suppa ◽  
May Chan ◽  
Susan Leake ◽  
Birute Karpavicius ◽  
...  
Keyword(s):  
United Kingdom ◽  
Case Control Study ◽  
Case Control ◽  
Melanoma Risk ◽  
The United Kingdom ◽  
Sunbed Use ◽  
Control Study ◽  
Large Case

scholarly journals Melanocytic Nevi, Nevus Genes, and Melanoma Risk in a Large Case-Control Study in the United Kingdom

2010 ◽  
Vol 19 (8) ◽  
pp. 2043-2054 ◽  
Author(s):  
Julia A. Newton-Bishop ◽  
Yu-Mei Chang ◽  
Mark M. Iles ◽  
John C. Taylor ◽  
Bert Bakker ◽  
...  
Keyword(s):  
United Kingdom ◽  
Case Control Study ◽  
Case Control ◽  
Melanoma Risk ◽  
Melanocytic Nevi ◽  
The United Kingdom ◽  
Control Study ◽  
Large Case

scholarly journals Pneumococcal Colonization Rates in Patients Admitted to a United Kingdom Hospital with Lower Respiratory Tract Infection: a Prospective Case-Control Study

2016 ◽  
Vol 54 (4) ◽  
pp. 944-949 ◽  
Author(s):  
Andrea M. Collins ◽  
Catherine M. K. Johnstone ◽  
Jenna F. Gritzfeld ◽  
Antonia Banyard ◽  
Carole A. Hancock ◽  
...  
Keyword(s):  
United Kingdom ◽  
Lower Respiratory Tract ◽  
Case Control Study ◽  
Case Control ◽  
The United Kingdom ◽  
Pneumococcal Colonization ◽  
Classical Culture ◽  
Control Study ◽  
Colonization Rates ◽  
Prospective Case Control Study

Current diagnostic tests are ineffective for identifying the etiological pathogen in hospitalized adults with lower respiratory tract infections (LRTIs). The association of pneumococcal colonization with disease has been suggested as a means to increase the diagnostic precision. We compared the pneumococcal colonization rates and the densities of nasal pneumococcal colonization by (i) classical culture and (ii) quantitative real-time PCR (qPCR) targetinglytAin patients with LRTIs admitted to a hospital in the United Kingdom and control patients. A total of 826 patients were screened for inclusion in this prospective case-control study. Of these, 38 patients were recruited, 19 with confirmed LRTIs and 19 controls with other diagnoses. Nasal wash (NW) samples were collected at the time of recruitment. Pneumococcal colonization was detected in 1 patient with LRTI and 3 controls (P= 0.6) by classical culture. By qPCR, pneumococcal colonization was detected in 10 LRTI patients and 8 controls (P= 0.5). Antibiotic usage prior to sampling was significantly higher in the LRTI group than in the control group (19 versus 3;P< 0.001). With a clinically relevant cutoff of >8,000 copies/ml on qPCR, pneumococcal colonization was found in 3 LRTI patients and 4 controls (P> 0.05). We conclude that neither the prevalence nor the density of nasal pneumococcal colonization (by culture and qPCR) can be used as a method of microbiological diagnosis in hospitalized adults with LRTI in the United Kingdom. A community-based study recruiting patients prior to antibiotic therapy may be a useful future step.

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