scholarly journals Checkpoint kinase inhibitor synergizes with DNA-damaging agents in G1checkpoint-defective neuroblastoma

2011 ◽  
Vol 129 (8) ◽  
pp. 1953-1962 ◽  
Author(s):  
Hong Xu ◽  
Irene Y. Cheung ◽  
Xiao X. Wei ◽  
Hoa Tran ◽  
Xiaoni Gao ◽  
...  
Keyword(s):  
Kinase Inhibitor ◽  
Checkpoint Kinase ◽  
Dna Damaging Agents ◽  
Checkpoint Kinase Inhibitor

scholarly journals AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies

2008 ◽  
Vol 7 (9) ◽  
pp. 2955-2966 ◽  
Author(s):  
S. D. Zabludoff ◽  
C. Deng ◽  
M. R. Grondine ◽  
A. M. Sheehy ◽  
S. Ashwell ◽  
...  
Keyword(s):  
Targeted Therapies ◽  
Kinase Inhibitor ◽  
Checkpoint Kinase ◽  
Checkpoint Kinase Inhibitor

Prexasertib, a checkpoint kinase inhibitor: from preclinical data to clinical development

2019 ◽  
Vol 85 (1) ◽  
pp. 9-20 ◽  
Author(s):  
Gesuino Angius ◽  
Silverio Tomao ◽  
Valeria Stati ◽  
Patrizia Vici ◽  
Vincenzo Bianco ◽  
...  
Keyword(s):  
Kinase Inhibitor ◽  
Clinical Development ◽  
Checkpoint Kinase ◽  
Preclinical Data ◽  
Checkpoint Kinase Inhibitor

Abstract 2499: Single agent activity of checkpoint kinase inhibitor PF-477736, in a MYC-driven lymphoma model

2010 ◽  
Author(s):  
Petranel T. Ferrão ◽  
Carleen Cullinane ◽  
Jeanette Raleigh ◽  
Sreesha Srinivasa ◽  
Wendy Levin ◽  
...  
Keyword(s):  
Kinase Inhibitor ◽  
Single Agent ◽  
Checkpoint Kinase ◽  
Checkpoint Kinase Inhibitor

Prexasertib: an investigational checkpoint kinase inhibitor for the treatment of high-grade serous ovarian cancer

2020 ◽  
Vol 29 (8) ◽  
pp. 779-792
Author(s):  
Giulio Evangelisti ◽  
Fabio Barra ◽  
Melita Moioli ◽  
Paolo Sala ◽  
Sara Stigliani ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Kinase Inhibitor ◽  
High Grade ◽  
Serous Ovarian Cancer ◽  
Checkpoint Kinase ◽  
Checkpoint Kinase Inhibitor

scholarly journals Checkpoint kinase inhibitor AZD7762 strongly sensitises urothelial carcinoma cells to gemcitabine

2017 ◽  
Vol 36 (1) ◽  
Author(s):  
Makoto Isono ◽  
Michèle J. Hoffmann ◽  
Maria Pinkerneil ◽  
Akinori Sato ◽  
Martin Michaelis ◽  
...  
Keyword(s):  
Urothelial Carcinoma ◽  
Kinase Inhibitor ◽  
Carcinoma Cells ◽  
Checkpoint Kinase ◽  
Checkpoint Kinase Inhibitor
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