scholarly journals Plasma insulin-like growth factor 1 is positively associated with low-grade prostate cancer in the Health Professionals Follow-up Study 1993-2004

2010 ◽  
Vol 128 (3) ◽  
pp. 660-667 ◽  
Author(s):  
Katharina Nimptsch ◽  
Elizabeth A. Platz ◽  
Michael N. Pollak ◽  
Stacey A. Kenfield ◽  
Meir J. Stampfer ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Growth Factor ◽  
Health Professionals ◽  
Plasma Insulin ◽  
Low Grade ◽  
Insulin Like Growth Factor ◽  
Follow Up Study

Plasma insulin-like growth factor-1 and binding protein-3 and subsequent risk of prostate cancer in the PSA era

2005 ◽  
Vol 16 (3) ◽  
pp. 255-262 ◽  
Author(s):  
Elizabeth A. Platz ◽  
Michael N. Pollak ◽  
Michael F. Leitzmann ◽  
Meir J. Stampfer ◽  
Walter C. Willett ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Growth Factor ◽  
Plasma Insulin ◽  
Binding Protein ◽  
Insulin Like Growth Factor ◽  
Subsequent Risk

scholarly journals Asthma and risk of lethal prostate cancer in the Health Professionals Follow-Up Study

2015 ◽  
Vol 137 (4) ◽  
pp. 949-958 ◽  
Author(s):  
Elizabeth A. Platz ◽  
Charles G. Drake ◽  
Kathryn M. Wilson ◽  
Siobhan Sutcliffe ◽  
Stacey A. Kenfield ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Health Professionals ◽  
Follow Up Study ◽  
Lethal Prostate Cancer

Aspirin Use and Lethal Prostate Cancer in the Health Professionals Follow-up Study

2019 ◽  
Vol 2 (2) ◽  
pp. 126-134 ◽  
Author(s):  
Mary K. Downer ◽  
Christopher B. Allard ◽  
Mark A. Preston ◽  
Kathryn M. Wilson ◽  
Stacey A. Kenfield ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Health Professionals ◽  
Follow Up Study ◽  
Lethal Prostate Cancer

scholarly journals Genetic Polymorphisms of the Glycine N-Methyltransferase and Prostate Cancer Risk in the Health Professionals Follow-Up Study

PLoS ONE ◽  
2014 ◽  
Vol 9 (5) ◽  
pp. e94683 ◽  
Author(s):  
Marcelo Chen ◽  
Yi-Ling Huang ◽  
Yu-Chuen Huang ◽  
Irene M. Shui ◽  
Edward Giovannucci ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Risk ◽  
Genetic Polymorphisms ◽  
Health Professionals ◽  
Prostate Cancer Risk ◽  
Follow Up Study

scholarly journals Association between Cognition and Serum Insulin-Like Growth Factor-1 in Middle-Aged & Older Men: An 8 Year Follow-Up Study

PLoS ONE ◽  
2016 ◽  
Vol 11 (4) ◽  
pp. e0154450 ◽  
Author(s):  
Shankar Tumati ◽  
Huibert Burger ◽  
Sander Martens ◽  
Yvonne T. van der Schouw ◽  
André Aleman
Keyword(s):  
Growth Factor ◽  
Serum Insulin ◽  
Older Men ◽  
Insulin Like Growth Factor ◽  
Middle Aged ◽  
Follow Up Study

scholarly journals Vasectomy and Risk of Aggressive Prostate Cancer: A 24-Year Follow-Up Study

2014 ◽  
Vol 32 (27) ◽  
pp. 3033-3038 ◽  
Author(s):  
Mohummad Minhaj Siddiqui ◽  
Kathryn M. Wilson ◽  
Mara M. Epstein ◽  
Jennifer R. Rider ◽  
Neil E. Martin ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Treatment ◽  
Specific Antigen ◽  
Prostate Cancer Risk ◽  
The United States ◽  
Low Grade ◽  
High Grade ◽  
Follow Up Study ◽  
Increased Risk

Purpose Conflicting reports remain regarding the association between vasectomy, a common form of male contraception in the United States, and prostate cancer risk. We examined prospectively this association with extended follow-up and an emphasis on advanced and lethal disease. Patients and Methods Among 49,405 US men in the Health Professionals Follow-Up Study, age 40 to 75 years at baseline in 1986, 6,023 patients with prostate cancer were diagnosed during the follow-up to 2010, including 811 lethal cases. In total, 12,321 men (25%) had vasectomies. We used Cox proportional hazards models to estimate the relative risk (RR) and 95% CIs of total, advanced, high-grade, and lethal disease, with adjustment for a variety of possible confounders. Results Vasectomy was associated with a small increased risk of prostate cancer overall (RR, 1.10; 95% CI, 1.04 to 1.17). Risk was elevated for high-grade (Gleason score 8 to 10; RR, 1.22; 95% CI, 1.03 to 1.45) and lethal disease (death or distant metastasis; RR, 1.19; 95% CI, 1.00 to 1.43). Among a subcohort of men receiving regular prostate-specific antigen screening, the association with lethal cancer was stronger (RR, 1.56; 95% CI, 1.03 to 2.36). Vasectomy was not associated with the risk of low-grade or localized disease. Additional analyses suggested that the associations were not driven by differences in sex hormone levels, sexually transmitted infections, or cancer treatment. Conclusion Our data support the hypothesis that vasectomy is associated with a modest increased incidence of lethal prostate cancer. The results do not appear to be due to detection bias, and confounding by infections or cancer treatment is unlikely.

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