Upregulation of caveolin-1 and CD147 expression in nasopharyngeal carcinoma enhanced tumor cell migration and correlated with poor prognosis of the patients

2009 ◽  
Vol 125 (8) ◽  
pp. 1832-1841 ◽  
Author(s):  
Zi-Ming Du ◽  
Chun-Fang Hu ◽  
Qiong Shao ◽  
Ma-Yan Huang ◽  
Chang-Wei Kou ◽  
...  
Keyword(s):  
Cell Migration ◽  
Nasopharyngeal Carcinoma ◽  
Tumor Cell ◽  
Poor Prognosis ◽  
Tumor Cell Migration ◽  
Caveolin 1 ◽  
Cd147 Expression

Phosphorylated Caveolin-1 Regulates Rho/ROCK-Dependent Focal Adhesion Dynamics and Tumor Cell Migration and Invasion

2008 ◽  
Vol 68 (20) ◽  
pp. 8210-8220 ◽  
Author(s):  
Bharat Joshi ◽  
Scott S. Strugnell ◽  
Jacky G. Goetz ◽  
Liliana D. Kojic ◽  
Michael E. Cox ◽  
...  
Keyword(s):  
Cell Migration ◽  
Tumor Cell ◽  
Focal Adhesion ◽  
Migration And Invasion ◽  
Cell Migration And Invasion ◽  
Tumor Cell Migration ◽  
Caveolin 1

scholarly journals Prodigiosin Inhibits Proliferation, Migration, and Invasion of Nasopharyngeal Cancer Cells

2018 ◽  
Vol 48 (4) ◽  
pp. 1556-1562 ◽  
Author(s):  
Yongze Liu ◽  
Han Zhou ◽  
Xiaofeng Ma ◽  
Chuanyao Lin ◽  
Ling Lu ◽  
...  
Keyword(s):  
Cell Migration ◽  
Nasopharyngeal Carcinoma ◽  
Tumor Cell ◽  
Cancer Cells ◽  
Cell Invasion ◽  
Nasopharyngeal Cancer ◽  
Migration And Invasion ◽  
Boyden Chamber ◽  
Cell Cycle Distribution ◽  
Tumor Cell Migration

Background/Aims: Nasopharyngeal carcinoma remains a devastating and difficult disease to treat. This study explores the antineoplastic effect of prodigiosin on nasopharyngeal cancer cells. Methods: Human nasopharyngeal carcinoma CNE2 cells and human normal nasopharyngeal epithelial NP69 cells were obtained and treated with prodigiosin or fluorouracil (5-FU). Colony formation assay was performed to screen for the optimal experimental concentrations of prodigiosin and 5-FU, and MTT assay was used to examine cell proliferative ability. Flow cytometry was used to examine cell cycle distribution, the scratch test was employed to examine cell migration, and Transwell migration assay (Boyden chamber) was used to study cell invasion. Results: The optimal concentrations of prodigiosin and 5-FU for treatment were 4 mg/L and 0.35 mg/L, respectively. Both prodigiosin and 5-FU inhibited tumor cell proliferation. The percentage of cells in G0/G1 phase was higher and the percentage of cells in S phase was lower in the prodigiosin and 5-FU groups than in the untreated groups. Both prodigiosin and 5-FU inhibited tumor cell migration and tumor cell invasion. Conclusions: Our results suggest that prodigiosin can inhibit proliferation, migration, and invasion of nasopharyngeal carcinoma cells.

scholarly journals A novel caveolin-1/p85α/Rab5/Tiam1/Rac1 signaling axis in tumor cell migration and invasion

2014 ◽  
Vol 7 (5) ◽  
pp. e972850 ◽  
Author(s):  
Jorge Díaz ◽  
Pablo Mendoza ◽  
Patricio Silva ◽  
Andrew FG Quest ◽  
Vicente A Torres
Keyword(s):  
Cell Migration ◽  
Tumor Cell ◽  
Migration And Invasion ◽  
Cell Migration And Invasion ◽  
Tumor Cell Migration ◽  
Caveolin 1 ◽  
Signaling Axis

scholarly journals miR-203 inhibits tumor cell migration and invasion via caveolin-1 in pancreatic cancer cells

2014 ◽  
Vol 7 (3) ◽  
pp. 658-662 ◽  
Author(s):  
LIFENG MIAO ◽  
XIANZE XIONG ◽  
YIXIN LIN ◽  
YAO CHENG ◽  
JIONG LU ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Cell Migration ◽  
Tumor Cell ◽  
Cancer Cells ◽  
Migration And Invasion ◽  
Cell Migration And Invasion ◽  
Tumor Cell Migration ◽  
Caveolin 1 ◽  
Pancreatic Cancer Cells
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