Diesel motor emissions and lung cancer mortality-Results of the second follow-up of a cohort study in potash miners

2009 ◽  
Vol 124 (8) ◽  
pp. 1900-1906 ◽  
Author(s):  
Angela Neumeyer-Gromen ◽  
Oliver Razum ◽  
Norbert Kersten ◽  
Andreas Seidler ◽  
Hajo Zeeb
Keyword(s):  
Lung Cancer ◽  
Cohort Study ◽  
Cancer Mortality ◽  
Lung Cancer Mortality

Relationship between glucosamine use and the risk of lung cancer: data from a nationwide prospective cohort study

2021 ◽  
pp. 2101399
Author(s):  
Guowei Li ◽  
Xuhui Zhang ◽  
Yingxin Liu ◽  
Junguo Zhang ◽  
Likang Li ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cohort Study ◽  
Family History ◽  
Prospective Cohort Study ◽  
Cancer Mortality ◽  
Prospective Cohort ◽  
Lung Cancer Mortality ◽  
Hazard Ratio ◽  
The Relationship

BackgroundResearch on glucosamine shows anti-inflammatory and anti-cancer benefits with a minimal adverse effects. We aimed to explore the relationship between use of glucosamine and risk of lung cancer and lung cancer mortality based on data from the large-scale nationwide prospective UK Biobank cohort study.MethodsParticipants were enrolled between the year 2006 and 2010 and followed up to 2020. Cox proportion hazards model were used to assess the relationship between glucosamine use and risk of lung cancer and lung cancer mortality. Subgroup analyses and sensitivity analyses were performed to explore the potential effect modifications and the robustness of main findings.ResultsA total of 439,393 participants (mean age: 56 years; 53% females) with a mean follow-up of 11 years were included for analyses. There were 82,603 (18.80%) participants reporting regular use of glucosamine at baseline. During follow-up, there were 1,971 (0.45%) lung cancer events documented. Glucosamine use was significantly associated with a decreased risk of lung cancer (hazard ratio=0.84, 95% CI: 0.75–0.92, p<0.001) and lung cancer mortality (hazard ratio=0.88, 95% CI: 0.81–0.96, p=0.002) in fully-adjusted models. A stronger association between glucosamine use and decreased lung cancer risk was observed in participants with a family history of lung cancer when compared to those without a family history.ConclusionRegular use of glucosamine was significantly related with decreased risk of lung cancer and lung cancer mortality, based on data from this nationwide prospective cohort study.

Lung Cancer Mortality and Occupational Exposure to Asbestos Among Telephone Linemen: A Historical Cohort Study in France

2006 ◽  
Vol 48 (11) ◽  
pp. 1166-1172 ◽  
Author(s):  
Djamila Meguellati-Hakkas ◽  
Diane Cyr ◽  
Isabelle St??cker ◽  
Jo??lle F??votte ◽  
Corinne Pilorget ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cohort Study ◽  
Occupational Exposure ◽  
Cancer Mortality ◽  
Lung Cancer Mortality ◽  
Historical Cohort ◽  
Historical Cohort Study

scholarly journals Neutrophil‐to‐lymphocyte ratio and risk of lung cancer mortality in a low‐risk population: A cohort study

2019 ◽  
Vol 145 (12) ◽  
pp. 3267-3275 ◽  
Author(s):  
Jihoon Kang ◽  
Yoosoo Chang ◽  
Jiin Ahn ◽  
Sukjoong Oh ◽  
Dong‐Hoe Koo ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cohort Study ◽  
Cancer Mortality ◽  
Lung Cancer Mortality ◽  
Low Risk ◽  
Neutrophil To Lymphocyte Ratio ◽  
Risk Population ◽  
Lymphocyte Ratio

Diesel motor exhaust and lung cancer mortality: reanalysis of a cohort study in potash miners

2013 ◽  
Vol 28 (2) ◽  
pp. 159-168 ◽  
Author(s):  
Matthias Möhner ◽  
Norbert Kersten ◽  
Johannes Gellissen
Keyword(s):  
Lung Cancer ◽  
Cohort Study ◽  
Cancer Mortality ◽  
Lung Cancer Mortality ◽  
Motor Exhaust

BMI, long-term changes in BMI, and risk of cancer mortality in a large cohort study.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. 1502-1502
Author(s):  
Niloofar Taghizadeh ◽  
Judith M. Vonk ◽  
H. Marike Boezen
Keyword(s):  
Breast Cancer ◽  
Prostate Cancer ◽  
Lung Cancer ◽  
Cohort Study ◽  
Mortality Risk ◽  
Cancer Mortality ◽  
Lung Cancer Mortality ◽  
Prostate Cancer Mortality ◽  
Risk Of Mortality ◽  
Cancer Mortality Risk

1502 Background: There are indications of an association between Body Mass Index (BMI) and risk of different cancer types. There is dispute whether this association differs between males and females. Methods: We studied the association of BMI at the first survey with risk of mortality from the most common types of cancer (lung, colorectal, breast and prostate cancer) in a large general population-based cohort study (Vlagtwedde-Vlaardingen, 1965-1990) with follow-up on mortality status until 2009. Additionally, we assessed this association based on tertiles of the annual change in BMI (defined as the difference between BMI at last survey and first survey divided by the time between last and first survey). We used 3 categories of BMI (< 25 kg/m2, 25-30 kg/m2, and ≥ 30 kg/m2) and changes in BMI (< 0.02 kg/m2/yr, 0.02-0.2 kg/m2/yr, and > 0.2 kg/m2/yr) in the analyses. The multivariate Cox regression model was adjusted for age, smoking, gender. Analyses were additionally stratified by gender and smoking. Results: Among all 8645 subjects, 1194 died due to cancer (lung cancer: 275; colorectal cancer: 134; breast cancer: 117; prostate cancer: 83). Mortality from all types of cancer was significantly increased in subjects with BMI > 30 kg/m2 (HR (95 % CI)) = 1.22 (1.00-1.48)), especially in females (1.38 (1.06-1.81)) and in never smokers (1.39 (1.02-1.90)). Prostate cancer mortality was significantly increased in males with BMI 25-30 kg/m2 (2.04 (1.90-3.83)) and > 30 kg/m2 (2.61 (1.02-6.67)). This association between prostate cancer mortality and BMI was higher in smokers. Lung cancer mortality risk was decreased in subjects with BMI 25-30 kg/m2 (0.71 (0.54-0.93)) and > 30 kg/m2 (0.82 (0.50-1.32)), especially in males, in smokers, and in smoking males. There were no significant associations between BMI and colorectal or breast cancer mortality nor between change in BMI and mortality from all analyzed types of cancer. Conclusions: We show that an increase in BMI is associated with an increased risk of mortality from all types of cancer in females and with an increased mortality risk from prostate cancer in males but with a decreased lung cancer mortality risk, especially in males. More research is needed into the biological mechanisms that link BMI to cancer.

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