scholarly journals Dietary prevention of malignant glioma aggressiveness, implications in oxidant stress and apoptosis

2008 ◽  
Vol 123 (2) ◽  
pp. 288-295 ◽  
Author(s):  
Daniel Pouliquen ◽  
Christophe Olivier ◽  
Eric Hervouet ◽  
Francois Pedelaborde ◽  
Emilie Debien ◽  
...  
Keyword(s):  
Malignant Glioma ◽  
Oxidant Stress ◽  
Dietary Prevention

Therapeutic management of malignant glioma in pregnancy: a case report highlighting clinical and radiological features at diagnosis and after intervention

2020 ◽  
Vol 3 (68) ◽  
pp. 147
Author(s):  
Ioniţă Ducu ◽  
Roxana-Elena Bohîlţea ◽  
Dan Teleanu ◽  
Natalia Ţurcan ◽  
Monica Mihaela Cîrstoiu
Keyword(s):  
Case Report ◽  
Malignant Glioma ◽  
Therapeutic Management ◽  
Radiological Features ◽  
In Pregnancy

Pathogenesis of Age-related Cataract: a systematic review of proteomic studies

2020 ◽  
Vol 17 ◽  
Author(s):  
Christina Karakosta ◽  
Argyrios Tzamalis ◽  
Michalis Aivaliotis ◽  
Ioannis Tsinopoulos
Keyword(s):  
Systematic Review ◽  
Oxidant Stress ◽  
Critical Role ◽  
Human Lens ◽  
Nuclear Cataract ◽  
Cataract Formation ◽  
Post Translational Modification ◽  
Ability To Act ◽  
Age Related

Background/Objective:: The aim of this systematic review is to identify all the available data on human lens proteomics with a critical role to age-related cataract formation in order to elucidate the physiopathology of the aging lens. Materials and Methods:: We searched on Medline and Cochrane databases. The search generated 328 manuscripts. We included nine original proteomic studies that investigated human cataractous lenses. Results:: Deamidation was the major age-related post-translational modification. There was a significant increase in the amount of αA-crystallin D-isoAsp58 present at all ages, while an increase in the extent of Trp oxidation was apparent in cataract lenses when compared to aged normal lenses. During aging, enzymes with oxidized cysteine at critical sites included GAPDH, glutathione synthase, aldehyde dehydrogenase, sorbitol dehydrogenase, and PARK7. Conclusion:: D-isoAsp in αA crystallin could be associated with the development of age-related cataract in human, by contributing to the denaturation of a crystallin, and decreasing its ability to act as a chaperone. Oxidation of Trp may be associated with nuclear cataract formation in human, while the role of oxidant stress in age-related cataract formation is dominant.

Hypoxia and the Malignant Glioma Microenvironment: Regulation and Implications for Therapy

2009 ◽  
Vol 2 (3) ◽  
pp. 263-284 ◽  
Author(s):  
L. Oliver ◽  
C. Olivier ◽  
F. Marhuenda ◽  
M. Campone ◽  
F. Vallette
Keyword(s):  
Malignant Glioma ◽  
Glioma Microenvironment

Specificity of cytokine profile and oxidant stress in patients with bronchial asthma

2006 ◽  
Vol 25 (2) ◽  
pp. 153-159
Author(s):  
Vladan Cosic ◽  
Vidosava Djordjevic ◽  
Gordana Bjelakovic ◽  
Jasmina Mimic-Oka ◽  
Dusica Pavlovic ◽  
...  
Keyword(s):  
Bronchial Asthma ◽  
Oxidant Stress ◽  
Cytokine Profile
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