Prognostic impact of orotate phosphoribosyl transferase among 5-fluorouracil metabolic enzymes in resectable colorectal cancers treated by oral 5-fluorouracil-based adjuvant chemotherapy

Takumi Ochiai; Kazuhiko Nishimura; Hajime Noguchi; Masayuki Kitajima; Akira Tsukada; Emiko Watanabe; Isao Nagaoka; Shunji Futagawa

doi:10.1002/ijc.21779

Prognostic impact of orotate phosphoribosyl transferase among 5-fluorouracil metabolic enzymes in resectable colorectal cancers treated by oral 5-fluorouracil-based adjuvant chemotherapy

International Journal of Cancer ◽

10.1002/ijc.21779 ◽

2006 ◽

Vol 118 (12) ◽

pp. 3084-3088 ◽

Cited By ~ 24

Author(s):

Takumi Ochiai ◽

Kazuhiko Nishimura ◽

Hajime Noguchi ◽

Masayuki Kitajima ◽

Akira Tsukada ◽

...

Keyword(s):

Adjuvant Chemotherapy ◽

Metabolic Enzymes ◽

Colorectal Cancers ◽

Prognostic Impact ◽

Orotate Phosphoribosyl Transferase ◽

Phosphoribosyl Transferase

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Prognostic impact of orotate phosphoribosyl transferase (OPRT) activity in resectable colorectal cancers (CRC) treated by 5-FU-based adjuvant chemotherapy

Journal of Clinical Oncology ◽

10.1200/jco.2004.22.14_suppl.3574 ◽

2004 ◽

Vol 22 (14_suppl) ◽

pp. 3574-3574 ◽

Cited By ~ 1

Author(s):

T. Ochiai ◽

M. Sugitani ◽

K. Nishimura ◽

H. Noguchi ◽

T. Okada ◽

...

Keyword(s):

Adjuvant Chemotherapy ◽

Colorectal Cancers ◽

Prognostic Impact ◽

Orotate Phosphoribosyl Transferase ◽

Phosphoribosyl Transferase

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Prognostic impact of orotate phosphoribosyl transferase activity in resectable colorectal cancers treated by 5-fluorouracil-based adjuvant chemotherapy

Journal of Surgical Oncology ◽

10.1002/jso.20553 ◽

2006 ◽

Vol 94 (1) ◽

pp. 45-50 ◽

Cited By ~ 7

Author(s):

Takumi Ochiai ◽

Kazuhiko Nishimura ◽

Hajime Noguchi ◽

Masayuki Kitajima ◽

Yuko Tsuruoka ◽

...

Keyword(s):

Adjuvant Chemotherapy ◽

Colorectal Cancers ◽

Transferase Activity ◽

Prognostic Impact ◽

Orotate Phosphoribosyl Transferase ◽

Phosphoribosyl Transferase

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Prognostic impact of orotate phosphoribosyl transferase (OPRT) activity in resectable colorectal cancers (CRC) treated by 5-FU-based adjuvant chemotherapy

Journal of Clinical Oncology ◽

10.1200/jco.2004.22.90140.3574 ◽

2004 ◽

Vol 22 (14_suppl) ◽

pp. 3574-3574

Author(s):

T. Ochiai ◽

M. Sugitani ◽

K. Nishimura ◽

H. Noguchi ◽

T. Okada ◽

...

Keyword(s):

Adjuvant Chemotherapy ◽

Colorectal Cancers ◽

Prognostic Impact ◽

Orotate Phosphoribosyl Transferase ◽

Phosphoribosyl Transferase

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Expression of orotate phosphoribosyl transferase in human pancreatic cancer: Implication for the efficacy of uracil and tegafur-based adjuvant chemotherapy

Oncology Reports ◽

10.3892/or.18.1.59 ◽

2007 ◽

Author(s):

Yoshinori Nio ◽

Tomoko Toga ◽

Riruke Maruyama ◽

Masakazu Fukushima

Keyword(s):

Pancreatic Cancer ◽

Adjuvant Chemotherapy ◽

Human Pancreatic Cancer ◽

Orotate Phosphoribosyl Transferase ◽

Phosphoribosyl Transferase

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Prognostic Impact of Fusobacterium nucleatum Depends on Combined Tumor Location and Microsatellite Instability Status in Stage II/III Colorectal Cancers Treated with Adjuvant Chemotherapy

Journal of Pathology and Translational Medicine ◽

10.4132/jptm.2018.11.29 ◽

2019 ◽

Vol 53 (1) ◽

pp. 40-49 ◽

Cited By ~ 12

Author(s):

Hyeon Jeong Oh ◽

Jung Ho Kim ◽

Jeong Mo Bae ◽

Hyun Jung Kim ◽

Nam-Yun Cho ◽

...

Keyword(s):

Adjuvant Chemotherapy ◽

Microsatellite Instability ◽

Fusobacterium Nucleatum ◽

Tumor Location ◽

Stage Ii ◽

Colorectal Cancers ◽

Prognostic Impact ◽

Combined Tumor

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Abstract 900: Associations between orotate phosphoribosyl transferase polymorphism and survival in patients with colorectal cancer treated with 5-FU-based adjuvant chemotherapy: A thirteen year follow-up study

10.1158/1538-7445.am10-900 ◽

2010 ◽

Author(s):

Ching-Yu Lai ◽

Shih-Ni Chang ◽

Fung-Chang Sung ◽

Ling-Ling Hsieh ◽

Reiping Tang ◽

...

Keyword(s):

Colorectal Cancer ◽

Adjuvant Chemotherapy ◽

Orotate Phosphoribosyl Transferase ◽

Phosphoribosyl Transferase ◽

Follow Up Study

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Comparison of orotate phosphoribosyl transferase (OPRT), thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) activity as prognostic factors in resectable colorectal cancers (CRC)

Journal of Clinical Oncology ◽

10.1200/jco.2005.23.16_suppl.3643 ◽

2005 ◽

Vol 23 (16_suppl) ◽

pp. 3643-3643

Author(s):

T. Ochiai ◽

K. Nishimura ◽

M. Kitajima ◽

H. Noguchi ◽

Y. Tsuruoka ◽

...

Keyword(s):

Prognostic Factors ◽

Thymidylate Synthase ◽

Dihydropyrimidine Dehydrogenase ◽

Colorectal Cancers ◽

Orotate Phosphoribosyl Transferase ◽

Phosphoribosyl Transferase

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Evaluation of 5-Fluorouracil Metabolic Enzymes as Predictors of Response to Adjuvant Chemotherapy Outcomes in Patients with Stage II/III Colorectal Cancer: A Decision-Curve Analysis

World Journal of Surgery ◽

10.1007/s00268-014-2738-1 ◽

2014 ◽

Vol 38 (12) ◽

pp. 3248-3256 ◽

Cited By ~ 11

Author(s):

Kohei Shigeta ◽

Yoshiyuki Ishii ◽

Hirotoshi Hasegawa ◽

Koji Okabayashi ◽

Yuko Kitagawa

Keyword(s):

Colorectal Cancer ◽

Adjuvant Chemotherapy ◽

Metabolic Enzymes ◽

Curve Analysis ◽

Stage Ii ◽

Decision Curve Analysis ◽

Predictors Of Response

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Inhibitors of orotate phosphoribosyl-transferase and orotidine-5'-phosphate decarboxylase from mouse ehrlich ascites cells: a procedure for analyzing the inhibition of a multi-enzyme complex

Biochemical Pharmacology ◽

10.1016/0006-2952(77)90293-3 ◽

1977 ◽

Vol 26 (23) ◽

pp. 2291-2296 ◽

Cited By ~ 34

Author(s):

Thomas W. Traut ◽

Mary Ellen Jones

Keyword(s):

Enzyme Complex ◽

Orotate Phosphoribosyl Transferase ◽

Phosphoribosyl Transferase ◽

Ehrlich Ascites ◽

Ehrlich Ascites Cells

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Prognostic impact of interhospital variation in adjuvant chemotherapy for patients with Stage II/III colorectal cancer: a nationwide study

Colorectal Disease ◽

10.1111/codi.14260 ◽

2018 ◽

Vol 20 (7) ◽

pp. O162-O172 ◽

Cited By ~ 1

Author(s):

K. Arakawa ◽

K. Kawai ◽

T. Tanaka ◽

K. Hata ◽

K. Sugihara ◽

...

Keyword(s):

Colorectal Cancer ◽

Adjuvant Chemotherapy ◽

Stage Ii ◽

Prognostic Impact ◽

Nationwide Study

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