GSTT1 andGSTM1 gene polymorphisms and gastric cancer in a high-risk italian population

2005 ◽  
Vol 115 (2) ◽  
pp. 284-289 ◽  
Author(s):  
Domenico Palli ◽  
Calogero Saieva ◽  
Simonetta Gemma ◽  
Giovanna Masala ◽  
Maria Jesus Gomez-Miguel ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
High Risk ◽  
Gene Polymorphisms ◽  
Italian Population

Interleukin-1 Gene Polymorphisms and Gastric Cancer Risk in a High-Risk Italian Population

2005 ◽  
Vol 100 (9) ◽  
pp. 1941-1948 ◽  
Author(s):  
D. Palli ◽  
C. Saieva ◽  
I. Luzzi ◽  
G. Masala ◽  
S. Topa ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
High Risk ◽  
Cancer Risk ◽  
Gene Polymorphisms ◽  
Interleukin 1 ◽  
Italian Population ◽  
Gastric Cancer Risk

Xenobiotic Pathway Gene Polymorphisms Associated with Gastric Cancer in High Risk Mizo-Mongoloid Population, Northeast India

Helicobacter ◽  
2016 ◽  
Vol 21 (6) ◽  
pp. 523-535 ◽  
Author(s):  
Souvik Ghatak ◽  
Ravi Prakash Yadav ◽  
Freda Lalrohlui ◽  
Payel Chakraborty ◽  
Soumee Ghosh ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
High Risk ◽  
Gene Polymorphisms ◽  
Northeast India ◽  
Pathway Gene ◽  
Mongoloid Population

scholarly journals Gene Polymorphisms of Micrornas in Helicobacter pylori-Induced High Risk Atrophic Gastritis and Gastric Cancer

PLoS ONE ◽  
2014 ◽  
Vol 9 (1) ◽  
pp. e87467 ◽  
Author(s):  
Juozas Kupcinskas ◽  
Thomas Wex ◽  
Alexander Link ◽  
Marcis Leja ◽  
Indre Bruzaite ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Helicobacter Pylori ◽  
High Risk ◽  
Atrophic Gastritis ◽  
Gene Polymorphisms

scholarly journals Accuracy of upper endoscopies with random biopsies to identify patients with gastric premalignant lesions who can safely be exempt from surveillance

2021 ◽  
Vol 24 (3) ◽  
pp. 680-690
Author(s):  
Michiel C. Mommersteeg ◽  
Stella A. V. Nieuwenburg ◽  
Wouter J. den Hollander ◽  
Lisanne Holster ◽  
Caroline M. den Hoed ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
High Risk ◽  
Low Risk ◽  
Premalignant Lesions ◽  
High Risk Patients ◽  
European Guidelines ◽  
Progression Of Disease ◽  
Risk Patients ◽  
Progression Risk

Abstract Introduction Guidelines recommend endoscopy with biopsies to stratify patients with gastric premalignant lesions (GPL) to high and low progression risk. High-risk patients are recommended to undergo surveillance. We aimed to assess the accuracy of guideline recommendations to identify low-risk patients, who can safely be discharged from surveillance. Methods This study includes patients with GPL. Patients underwent at least two endoscopies with an interval of 1–6 years. Patients were defined ‘low risk’ if they fulfilled requirements for discharge, and ‘high risk’ if they fulfilled requirements for surveillance, according to European guidelines (MAPS-2012, updated MAPS-2019, BSG). Patients defined ‘low risk’ with progression of disease during follow-up (FU) were considered ‘misclassified’ as low risk. Results 334 patients (median age 60 years IQR11; 48.7% male) were included and followed for a median of 48 months. At baseline, 181/334 (54%) patients were defined low risk. Of these, 32.6% were ‘misclassified’, showing progression of disease during FU. If MAPS-2019 were followed, 169/334 (51%) patients were defined low risk, of which 32.5% were ‘misclassified’. If BSG were followed, 174/334 (51%) patients were defined low risk, of which 32.2% were ‘misclassified’. Seven patients developed gastric cancer (GC) or dysplasia, four patients were ‘misclassified’ based on MAPS-2012 and three on MAPS-2019 and BSG. By performing one additional endoscopy 72.9% (95% CI 62.4–83.3) of high-risk patients and all patients who developed GC or dysplasia were identified. Conclusion One-third of patients that would have been discharged from GC surveillance, appeared to be ‘misclassified’ as low risk. One additional endoscopy will reduce this risk by 70%.

Role of Xenobiotic-Metabolizing Enzyme Gene Polymorphisms and Interactions with Environmental Factors in Susceptibility to Gastric Cancer in Kashmir Valley

2009 ◽  
Vol 40 (1-2) ◽  
pp. 26-32 ◽  
Author(s):  
Manzoor A. Malik ◽  
Rohit Upadhyay ◽  
Rama D. Mittal ◽  
Showket A. Zargar ◽  
Dinesh R. Modi ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Environmental Factors ◽  
Gene Polymorphisms ◽  
Kashmir Valley ◽  
Enzyme Gene ◽  
Metabolizing Enzyme

No Impact of Repeated Endoscopic Screens on Gastric Cancer Mortality in a Prospectively Followed Chinese Population at High Risk

2002 ◽  
Vol 34 (1) ◽  
pp. 22-28 ◽  
Author(s):  
B. Riecken ◽  
R. Pfeiffer ◽  
J.L. Ma ◽  
M.L. Jin ◽  
J.Y. Li ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
High Risk ◽  
Cancer Mortality ◽  
Chinese Population

Identifying and Preventing High-risk Gastric Cancer Individuals With CDH1 Mutations

2008 ◽  
Vol 247 (4) ◽  
pp. 714-715 ◽  
Author(s):  
Dimosthenis Ziogas ◽  
Georgios Baltogiannis ◽  
Michael Fatouros ◽  
Dimitrios H. Roukos
Keyword(s):  
Gastric Cancer ◽  
High Risk
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