scholarly journals p53 mutation profiling of multiple esophageal carcinoma using laser capture microdissection to demonstrate field carcinogenesis

2005 ◽  
Vol 113 (1) ◽  
pp. 22-28 ◽  
Author(s):  
Shuhei Ito ◽  
Takefumi Ohga ◽  
Hiroshi Saeki ◽  
Toshihiko Nakamura ◽  
Masayuki Watanabe ◽  
...  
Keyword(s):  
Esophageal Carcinoma ◽  
Laser Capture Microdissection ◽  
P53 Mutation ◽  
Field Carcinogenesis ◽  
Laser Capture ◽  
Mutation Profiling

p53 Mutation Analysis of Low-Grade Dysplasia and High-Grade Dysplasia/Carcinoma in situ of the Esophagus Using Laser Capture Microdissection

Oncology ◽  
2006 ◽  
Vol 71 (3-4) ◽  
pp. 237-245 ◽  
Author(s):  
Maki Kobayashi ◽  
Hiroshi Kawachi ◽  
Toichiro Takizawa ◽  
Keisuke Uchida ◽  
Masaki Sekine ◽  
...  
Keyword(s):  
Mutation Analysis ◽  
Laser Capture Microdissection ◽  
Carcinoma In Situ ◽  
P53 Mutation ◽  
High Grade Dysplasia ◽  
Low Grade ◽  
High Grade ◽  
Low Grade Dysplasia ◽  
Laser Capture

Isolating Human Notochord Using Laser Capture Microdissection

2016 ◽  
Vol 77 (S 02) ◽  
Author(s):  
Youssef Yakkioui ◽  
Remco Santegoeds ◽  
Koo van Overbeeke ◽  
Andreas Herrler ◽  
Yasin Temel
Keyword(s):  
Laser Capture Microdissection ◽  
Laser Capture

scholarly journals Stromal MED12 exon 2 mutations in complex fibroadenomas of the breast

2020 ◽  
pp. jclinpath-2020-207062
Author(s):  
Edaise M da Silva ◽  
Francisco Beca ◽  
Ana Paula Martins Sebastiao ◽  
Melissa P Murray ◽  
Catarina Silveira ◽  
...  
Keyword(s):  
Reverse Transcriptase ◽  
Laser Capture Microdissection ◽  
Sanger Sequencing ◽  
Mediator Complex ◽  
Telomerase Reverse Transcriptase ◽  
Exon 2 ◽  
Stromal Component ◽  
Hotspot Mutations ◽  
Laser Capture

AimsHere we explore the presence of mediator complex subunit 12 (MED12) exon 2 and telomerase reverse transcriptase (TERT) promoter hotspot mutations in complex fibroadenomas (CFAs) of the breast.MethodsThe stromal components from 18 CFAs were subjected to Sanger sequencing of MED12 exon 2 and the TERT promoter hotspot loci. The epithelial and stromal components of two MED12 mutated CFAs were subjected to laser capture microdissection, and Sanger sequencing of MED12 exon 2, TERT promoter and PIK3CA exons 9 and 20, separately.ResultsMED12 exon 2 mutations were identified in the stroma of 17% of CFAs. The analyses of epithelial and stromal components, microdissected separately, revealed that MED12 mutations were restricted to the stroma. No TERT promoter or PIK3CA mutations in exons 9 and 20 were detected in analysed CFAs.ConclusionsLike conventional fibroadenomas, MED12 exon 2 mutations appear to be restricted to the stromal component of CFAs, supporting the notion that CFAs are stromal neoplasms.

scholarly journals Laser capture microdissection for transcriptomic profiles in human skin biopsies

2018 ◽  
Vol 19 (1) ◽  
Author(s):  
Silvia Santoro ◽  
Ignazio Diego Lopez ◽  
Raffaella Lombardi ◽  
Andrea Zauli ◽  
Ana Maria Osiceanu ◽  
...  
Keyword(s):  
Human Skin ◽  
Laser Capture Microdissection ◽  
Skin Biopsies ◽  
Laser Capture

Thermal modeling of Laser Capture Microdissection

1998 ◽  
Vol 37 (31) ◽  
pp. 7378 ◽  
Author(s):  
Seth R. Goldstein ◽  
Philip G. McQueen ◽  
Robert F. Bonner
Keyword(s):  
Laser Capture Microdissection ◽  
Thermal Modeling ◽  
Laser Capture
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