scholarly journals CHEK2*1100delC and male breast cancer risk in Israel

2003 ◽  
Vol 108 (3) ◽  
pp. 479-480 ◽  
Author(s):  
Tal Ohayon ◽  
Inbar Gal ◽  
Ruth Gershoni Baruch ◽  
Csilla Szabo ◽  
Eitan Friedman
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Male Breast Cancer ◽  
Male Breast ◽  
Chek2 1100Delc

962: Association of SULT1A1 Arg213His polymorphism with male breast cancer risk: a case−control study in Italy

2014 ◽  
Vol 50 ◽  
pp. S234-S235
Author(s):  
P. Rizzolo ◽  
V. Silvestri ◽  
G. Giannini ◽  
L. Varesco ◽  
A. Viel ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Male Breast Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Male Breast ◽  
Control Study

Neurofibromatosis with male breast cancer-risk factor or co-incidence? Report of two rare cases

2015 ◽  
Vol 35 (1) ◽  
pp. 29-32 ◽  
Author(s):  
Megha Tandon ◽  
Pankaj Panwar ◽  
Praveen Garg ◽  
Chintamani ◽  
Fauzia Siraj
Keyword(s):  
Breast Cancer ◽  
Risk Factor ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Male Breast Cancer ◽  
Breast Cancer Risk Factor ◽  
Male Breast ◽  
Cancer Risk Factor

scholarly journals Electromagnetic Field Exposure and Male Breast Cancer Risk: A Meta-analysis of 18 Studies

2013 ◽  
Vol 14 (1) ◽  
pp. 523-528 ◽  
Author(s):  
Jing-Wen Sun ◽  
Xiao-Rong Li ◽  
Hong-Yu Gao ◽  
Jie-Yun Yin ◽  
Qin Qin ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Electromagnetic Field ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Male Breast Cancer ◽  
Meta Analysis ◽  
Male Breast ◽  
Field Exposure

961: Low-penetrance alleles and male breast cancer risk: Results from a multicenter study in Italy

2014 ◽  
Vol 50 ◽  
pp. S234
Author(s):  
V. Silvestri ◽  
P. Rizzolo ◽  
G. Giannini ◽  
S. Tommasi ◽  
A. Viel ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Male Breast Cancer ◽  
Multicenter Study ◽  
Male Breast

DNA repair and metabolic gene polymorphisms and male breast cancer risk

2008 ◽  
Vol 6 (9) ◽  
pp. 97
Author(s):  
M. Falchetti ◽  
P. Rizzolo ◽  
R. Lupi ◽  
K. Ceccarelli ◽  
G. Masala ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Dna Repair ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Male Breast Cancer ◽  
Gene Polymorphisms ◽  
Male Breast ◽  
Metabolic Gene

scholarly journals Evaluation of CYP17A1 and CYP1B1 polymorphisms in male breast cancer risk

2019 ◽  
Vol 8 (8) ◽  
pp. 1224-1229 ◽  
Author(s):  
Piera Rizzolo ◽  
Valentina Silvestri ◽  
Virginia Valentini ◽  
Veronica Zelli ◽  
Agostino Bucalo ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Male Breast Cancer ◽  
Estrogen Receptor Status ◽  
Male Breast ◽  
Allelic Discrimination ◽  
Breast Cancer Predisposition ◽  
Mutational Status

Breast cancer in men is a rare and still poorly characterized disease. Inherited mutations in BRCA1, BRCA2 and PALB2 genes, as well as common polymorphisms, play a role in male breast cancer genetic predisposition. Male breast cancer is considered a hormone-dependent tumor specifically related to hyperestrogenism. Polymorphisms in genes involved in estrogen biosynthesis and metabolism pathways, such as CYP17A1 and CYP1B1, have been associated with breast cancer risk. Here, we aimed to investigate the role of CYP17A1 and CYP1B1 polymorphisms in male breast cancer risk. A series of 597 male breast cancer cases and 1022 male controls, recruited within the Italian Multicenter Study on male breast cancer, was genotyped for CYP17A1 rs743572, CYP1B1 rs1056836 and rs1800440 polymorphisms by allelic discrimination real-time PCR with TaqMan probes. Associations with male breast cancer risk were estimated using logistic regression. No statistically significant associations between male breast cancer risk and the three analyzed polymorphisms emerged. Similar results were obtained also when BRCA1/2 mutational status was considered. No significant differences in the distribution of the genotypes according to estrogen receptor status emerged. In conclusion, our study, based on a large series of male breast cancer cases, is likely to exclude a relevant role of CYP17A1 and CYP1B1 polymorphisms in male breast cancer predisposition. Overall, these results add new data to the increasing evidence that polymorphisms in these genes may not be associated with breast cancer risk.

scholarly journals Prediagnostic Sex Steroid Hormones in Relation to Male Breast Cancer Risk

2015 ◽  
Vol 33 (18) ◽  
pp. 2041-2050 ◽  
Author(s):  
Louise A. Brinton ◽  
Tim J. Key ◽  
Laurence N. Kolonel ◽  
Karin B. Michels ◽  
Howard D. Sesso ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Body Mass Index ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Body Mass ◽  
Male Breast Cancer ◽  
Case Control ◽  
Male Breast ◽  
Breast Cancers ◽  
Blood Draw

Purpose Although previous studies have implicated a variety of hormone-related risk factors in the etiology of male breast cancers, no previous studies have examined the effects of endogenous hormones. Patients and Methods Within the Male Breast Cancer Pooling Project, an international consortium comprising 21 case-control and cohort investigations, a subset of seven prospective cohort studies were able to contribute prediagnostic serum or plasma samples for hormone quantitation. Using a nested case-control design, multivariable unconditional logistic regression analyses estimated odds ratios and 95% CIs for associations between male breast cancer risk and 11 individual estrogens and androgens, as well as selected ratios of these analytes. Results Data from 101 cases and 217 matched controls were analyzed. After adjustment for age and date of blood draw, race, and body mass index, androgens were found to be largely unrelated to risk, but circulating estradiol levels showed a significant association. Men in the highest quartile had an odds ratio of 2.47 (95% CI, 1.10 to 5.58) compared with those in the lowest quartile (trend P = .06). Assessment of estradiol as a ratio to various individual androgens or sum of androgens showed no further enhancement of risk. These relations were not significantly modified by either age or body mass index, although estradiol was slightly more strongly related to breast cancers occurring among younger (age < 67 years) than older men. Conclusion Our results support the notion of an important role for estradiol in the etiology of male breast cancers, similar to female breast cancers.

Male breast cancer: risk to daughters

The Lancet ◽  
1999 ◽  
Vol 353 (9159) ◽  
pp. 1186-1187 ◽  
Author(s):  
Kari Hemminki ◽  
Pauli Vaittinen
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Male Breast Cancer ◽  
Male Breast
Sign in / Sign up

Export Citation Format

Share Document