Increased emotional distress in daughters of breast cancer patients is associated with decreased natural cytotoxic activity, elevated levels of stress hormones and decreased secretion of Th1 cytokines

2002 ◽  
Vol 100 (3) ◽  
pp. 347-354 ◽  
Author(s):  
Miri Cohen ◽  
Ehud Klein ◽  
Abraham Kuten ◽  
Geta Fried ◽  
Oren Zinder ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cytotoxic Activity ◽  
Cancer Patients ◽  
Emotional Distress ◽  
Stress Hormones ◽  
Breast Cancer Patients ◽  
Th1 Cytokines ◽  
Natural Cytotoxic

Interleukin-2 induces cytotoxic activity in lymphocytes from regional axillary nodes of breast cancer patients

Cancer ◽  
1988 ◽  
Vol 61 (4) ◽  
pp. 629-634 ◽  
Author(s):  
Felix Bonilla ◽  
Melchor Alvarez-mon ◽  
Francisco Merino ◽  
Antonio De La Hera ◽  
José Enrique Alés ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cytotoxic Activity ◽  
Cancer Patients ◽  
Interleukin 2 ◽  
Breast Cancer Patients ◽  
Axillary Nodes

Effect of pretreatment distress on daily fatigue after chemotherapy for breast cancer

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 9090-9090
Author(s):  
S. C. Higgins ◽  
G. H. Montgomery ◽  
D. H. Bovbjerg
Keyword(s):  
Breast Cancer ◽  
Side Effects ◽  
Cancer Patients ◽  
Emotional Distress ◽  
Repeated Measures ◽  
Breast Cancer Patients ◽  
Outpatient Chemotherapy ◽  
Specific Effects ◽  
Post Infusion ◽  
Time Specific

9090 Background: Fatigue is one of the most frequently reported and aversive side effects of cancer chemotherapy. Prospective research has found that cancer patients’ levels of emotional distress prior to treatment are predictive of other side effects (e.g., nausea), but studies of such effects on fatigue are lacking. The present study prospectively tested the hypothesis that patients’ levels of emotional distress in the clinic prior to their first treatment infusion would predict the severity of their post-infusion fatigue. Methods: Sixty Stage I (32.6%) and II (67.4%) breast cancer patients (mean age=44.5 yrs), receiving standard outpatient chemotherapy (e.g., CMF), participated. The independent variable, emotional distress, was assessed (0–100) with a visual analog scale (VAS). The dependent variable, post treatment fatigue (PTF) was assessed (0–100) over each of the subsequent 6 days using end-of-day diaries, which also included assessment of distress (0–100). To explore temporal specificity, pretreatment distress was assessed for “last night”, “this morning” and “right now.” Results: Consistent with previous reports, PTF levels peaked at day 2 and began to decline after day 3, although they remained elevated across the period (p<.026). Repeated measures analysis indicated a significant main effect of pretreatment distress “right now” on PTF (p<.009); prior distress levels were less predictive. Additional regression analyses, controlling for pretreatment fatigue and daily distress, revealed a strongly selective effect of pretreatment distress on post peak PTF on days 5 (p<.002) and 6 (p<.026). Conclusions: This study is the first to demonstrate time-specific effects of pretreatment distress on PTF. Possible mechanisms of these effects now warrant investigation, as do possible benefits of brief interventions to reduce distress immediately prior to treatment. No significant financial relationships to disclose.

Emotional distress prior to chemotherapy and delayed nausea in breast cancer patients

2008 ◽  
Vol 26 (15_suppl) ◽  
pp. 9527-9527
Author(s):  
S. C. Higgins ◽  
D. H. Bovbjerg ◽  
G. R. Morrow ◽  
J. A. Roscoe
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Emotional Distress ◽  
Breast Cancer Patients ◽  
Delayed Nausea

Evaluation of a Psychosocial Intervention on Social Support Perceived Control, Coping Strategies, Emotional Distress, and Quality of Life of Breast Cancer Patients

2011 ◽  
Vol 108 (3) ◽  
pp. 923-942 ◽  
Author(s):  
Florence Cousson-Géalie ◽  
Marilou Bruchon-Schweitzer ◽  
Thierry Atzeni ◽  
Nadine Houede
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Social Support ◽  
Cancer Patients ◽  
Emotional Distress ◽  
Perceived Control ◽  
Psychosocial Intervention ◽  
Psychological Intervention ◽  
Breast Cancer Patients

The purpose of this research was to demonstrate that a specific psychosocial intervention changes reactions to cancer and quality of life. This study was carried out on 66 patients with a first breast cancer. Patients were randomly divided into two groups: a specific intervention group (G1, 8 sessions) or a support group (G2, 8 sessions). A control group (G3) was composed of patients who refused to participate in psychological intervention. Social support, perceived control, repression of emotions, coping strategies, emotional distress, and quality of life were assessed one week before (T1) and at the end (T2) of the psychological intervention. Results showed that G1 did not have significantly modified quality of life or psychological scores. Patients of G2 had poorer emotional quality of life, use of internal causal attributions, and minimized their illness at T1 as compared to patients of G3. At Time 2 these differences were not observed.

scholarly journals Group interventions to reduce emotional distress and fatigue in breast cancer patients: a 9-month follow-up pragmatic trial

2017 ◽  
Vol 117 (10) ◽  
pp. 1442-1449 ◽  
Author(s):  
Charlotte Grégoire ◽  
Isabelle Bragard ◽  
Guy Jerusalem ◽  
Anne-Marie Etienne ◽  
Philippe Coucke ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Emotional Distress ◽  
Pragmatic Trial ◽  
Breast Cancer Patients ◽  
Group Interventions
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